NMR and EPR

Molecular systems important to biology, environmental remediation and sustainability are studied using a suite of nuclear magnetic resonance (NMR) spectrometers with frequencies ranging from 300 to 850 MHz. A pair of electron paramagnetic resonance (EPR) spectrometers complement the capability. See a complete list of NMR and EPR instruments.

Description

Interfacial and in situ biology—Innovative NMR instrumentation and techniques for probing properties of macromolecular cellular assemblies and in situ and ex situ metabolic processes, as well as for exploring biological membrane proteins in the solid state. Unique EPR and variable-temperature NMR approaches to explore structure and properties of redox metal centers cell biology.

Environmental chemistry— EMSL offers a unique NMR system for radiological studies. Users can perform magic angle spinning of highly radioactive samples with a novel hermetically sealed 3.2mm NMR probe. These tools allow users to apply NMR techniques to critical areas of radiological research, including the study of radioactive waste processing and storage.

Interfacial and in situ chemistry—Leading-edge solid-state NMR probe technology to analyze and quantify properties of advanced energy materials, fuel cells and real-time catalytic processes. High power pulsed field gradient diffusion capabilities for liquid and solid samples.

EMSL offers unique and custom NMR and EPR tools, including probes for specialized studies.

  • NMR spectrometers, ranging from 300 MHz to 850 MHz for high-field liquid-state, solid-state and micro-imaging techniques
  • W- and X-band pulsed EPR spectremeter for probing metal centers in biological and materials systems
  • NMR metabolomics capabilities
  • Extreme-temperature probes, both high and low temperatures
  • Virtual NMR tools for remote access to spectrometer systems.

Instruments

Highlighted Research Applications Characterization of natural and soil organic matter (NOM and SOM) CO2 sequestration investigations via high-...
Custodian(s): Sarah D Burton, David Hoyt
Research Applications Characterization of quadrupolar nuclei for inorganic and biological materials and natural sediments Cryogenic NMR capabilities...
Highlighted Research Applications EMSL's Bruker 500-MHz WB spectrometer is uniquely tailored for in vivo studies: Microbial biofilms relevant to...
Type of Instrument:
Nuclear Magnetic Resonance Spectrometer (NMR)
Research Applications Dynamics studies via 2H NMR Characterization of quadrupolar nuclei for materials and biological samples Characterization of...
Highlighted Research Applications Structural biology Protein structure and dynamics Nuclei acid structure and dynamics. Metabolomics Eukaryotic and...
Custodian(s): Nancy Isern, David Hoyt

Publications

Li-S batteries hold great potential for next-generation, large-format power source applications; yet, the fundamental understanding of the...
Solid-state transport and electrochemical properties of Ti-doped hematite (001) epitaxial thin films (6.0, 8.3, and 16.6 at% Ti) were probed to...
Subsurface injection of CO2 for enhanced hydrocarbon recovery, hydraulic fracturing of unconventional reservoirs, and geologic carbon sequestration...
The Chesapeake Bay, the largest and most productive estuary in the US, suffers from varying degrees of water quality issues fueled by both point and...
Recently, we have demonstrated that considerable inherent sensitivity gains are attained in MAS NMR spectra acquired by nonuniform sampling (NUS) and...

Science Highlights

Posted: May 09, 2016
The Science More rapid and improved estimates of metabolic fluxes in cells are possible thanks to a new technique that combines 13C-Metabolic Flux...
Posted: April 22, 2016
Scientists at Pacific Northwest National Laboratory, or PNNL, EMSL and the University of Washington collaborated to study rechargeable zinc-...
Posted: November 20, 2015
The Science Phototrophic microbial mats are among the most diverse ecosystems in nature. These self-sustaining natural ecosystems are composed of...
Posted: October 20, 2015
The Science Permafrost soils near the North Pole contain roughly twice the amount of carbon stored in the atmosphere today; but for now, most of...
Posted: September 23, 2015
The Science Natural organic matter (NOM) is a mixture of organic molecules derived primarily from the natural decay of plant matter. Understanding...

Instruments

This is a proposal to use advanced solid-state NMR methods to elucidate the architecture and arrangement of cell walls of plants, grass species in...
This proposal aims to provide molecular insight into elementary reaction steps and their kinetics in condensed phases at an atomic and molecular...
A critical step in the lignocellulosic biofuels pipeline is the extraction of fermentable sugars from plant biomass. Extracellular fungal enzymes are...
The Joint Center for Energy Storage Research (JCESR) is performing transformational research to overcome critical scientific and technical barriers...
Our research program strives to provide new insight into the fundamental molecular-scale dynamics, energetics, and reactivity of geochemically...

Molecular systems important to biology, environmental remediation and sustainability are studied using a suite of nuclear magnetic resonance (NMR) spectrometers with frequencies ranging from 300 to 850 MHz. A pair of electron paramagnetic resonance (EPR) spectrometers complement the capability. See a complete list of NMR and EPR instruments.

Pages

Leads

(509) 371-7094

Dr. Washton is a key player in coupling solid-state NMR  (ssNMR) with computational chemistry for predictions of reaction site structure and kinetics, and to provide users with an integrated system for making predictions of NMR parameters based...