NMR and EPR

Molecular systems important to biology, environmental remediation and sustainability are studied using a suite of nuclear magnetic resonance (NMR) spectrometers with frequencies ranging from 300 to 850 MHz. A pair of electron paramagnetic resonance (EPR) spectrometers complement the capability. See a complete list of NMR and EPR instruments.

Description

Interfacial and in situ biology—Innovative NMR instrumentation and techniques for probing properties of macromolecular cellular assemblies and in situ and ex situ metabolic processes, as well as for exploring biological membrane proteins in the solid state. Unique EPR and variable-temperature NMR approaches to explore structure and properties of redox metal centers critical catalysis, environmental chemistry and cell biology.

Environmental chemistry— EMSL offers a unique NMR system for radiological studies. Users can perform magic angle spinning of highly radioactive samples with a novel hermetically sealed 3.2mm NMR probe. These tools allow users to apply NMR techniques to critical areas of radiological research, including the study of radioactive waste processing and storage.

Interfacial and in situ chemistry—Leading-edge solid-state NMR probe technology to analyze and quantify properties of advanced energy materials, fuel cells and real-time catalytic processes. High power pulsed field gradient diffusion capabilities for liquid and solid samples.

EMSL offers unique and custom NMR and EPR tools, including probes for specialized studies.

  • NMR spectrometers, ranging from 300 MHz to 850 MHz for high-field liquid-state, solid-state and micro-imaging techniques
  • W- and X-band pulsed EPR spectremeter for probing metal centers in biological and materials systems
  • NMR metabolomics capabilities
  • Extreme-temperature probes, both high and low temperatures
  • Virtual NMR tools for remote access to spectrometer systems.

Instruments

Highlighted Research Applications Structural biology Protein structure and dynamics Nuclei acid structure and dynamics Metabolomics Eukaryotic and...
Custodian(s): David Hoyt, Nancy Isern
Highlighted Research Applications Characterization of quadrupolar nuclei for materials and biological samples In situ catalysis investigations via...
Research applications Samples containing paramagnetics Soils (SOM and NOM) Metal oxide materials for catalysis applications Researchers may operate...
Highlighted Research Applications Characterization of natural and soil organic matter (NOM and SOM) CO2 sequestration investigations via high-...
Custodian(s): Sarah D Burton, David Hoyt
Research Applications Characterization of quadrupolar nuclei for inorganic and biological materials and natural sediments Cryogenic NMR capabilities...

Publications

Melanoma is a malignant tumor of melanocytes. Although extensive investigations have been done to study metabolic changes in primary melanoma in...
Dual beam depth profiling strategy has been widely adopted in ToF-SIMS depth profiling, in which two basic operation modes, interlaced mode and non-...
Currently, nuclear wastes are commonly immobilized into glasses because of their long-term durability. Exposure to water for long periods of time,...
We employed deep sequencing technology to identify transcriptional adaptation of the euryhaline unicellular cyanobacterium Synechococcus sp. PCC 7002...
Shale formations play fundamental roles in large-scale geologic carbon sequestration (GCS) aimed primarily to mitigate climate change, and in smaller...

Science Highlights

Posted: August 14, 2015
Active sites are where catalytic reactions occur; however, slow or failed sties result in higher costs and lower production rates.  To improve...
Posted: March 27, 2015
Zeolites are widely used in industry as catalysts, but many of the characteristics of these materials are challenging to understand and predict. Led...
Posted: March 02, 2015
A new zinc-polyiodide redox flow battery developed at Pacific Northwest National Laboratory with EMSL resources uses an electrolyte with more than...
Posted: January 15, 2015
A team of scientists with Pacific Northwest National Laboratory, EMSL, Marine Biological Laboratory and The Pennsylvania State University grew two...
Posted: November 21, 2014
The Science Carbon dioxide (CO2) sequestration in deep subsurface environments has received significant attention and investment as a way to reduce...

Instruments

This is a proposal to use advanced solid-state NMR methods to elucidate the architecture and arrangement of cell walls of plants, grass species in...
Three related research programs at PNNL focus on developing bioinspired electrocatalysts for energy storage, energy production, or carbon fixation...
The objective of this proposed work is to characterize the chemisorption products of CO2 interacting with solid-supported amine materials. The aim...
A priority goal of the United States Department of Energy is to dispose of nuclear wastes accumulated in underground tanks at the Hanford Nuclear...
The goal of this proposal is to demonstrate a unique capability to be enabled in the EMSL, the integration of leading-edge cryogenic NMR and EPR...

Molecular systems important to biology, environmental remediation and sustainability are studied using a suite of nuclear magnetic resonance (NMR) spectrometers with frequencies ranging from 300 to 850 MHz. A pair of electron paramagnetic resonance (EPR) spectrometers complement the capability. See a complete list of NMR and EPR instruments.

Pages

Leads

(509) 371-7094

Dr. Washton is a key player in coupling solid-state NMR  (ssNMR) with computational chemistry for predictions of reaction site structure and kinetics, and to provide users with an integrated system for making predictions of NMR parameters based...