Quiet Wing

EMSL’s Quiet Wing supports a wide range of research areas, including climate, biological, environmental and energy systems, of importance to the Department of Energy. It is among the most advanced quiet laboratories in the world for high-resolution imaging capabilities.

The Quiet Wing is a unique research environment housing a suite of ultrasensitive microscopy and scanning instruments. It was designed to help accelerate critical science by allowing state-of-the-art ultrasensitive microscopy equipment to operate at optimal resolution. A temperature-controlled facility, the wing’s design eliminates or reduces to a minimum the vibrations, acoustics and electromagnetic noise that can interfere with the resolution of ultrasensitive scientific instrumentation.

The 9,500-square-foot facility features eight quiet laboratory cells and a sample preparation area. The wing currently houses seven microscopy instruments and has room for one more. These microscopes are just a few of the extensive suite of microscopy instruments at EMSL available for scientific inquiry.

EMSL's microscopy capabilities, including those in the Quiet Wing, are available to the scientific community at typically no cost for openly published research. Scientists gain access to instruments and collaborate with onsite microscopy experts through a peer-reviewed proposal process. Learn more about becoming an EMSL user.

Learn more about each instrument and the science it advances on EMSL's YouTube channel and watch the video below on the Quiet Wing.

A new DTEM – Dynamic Transmission Electron Microscope – is under development at EMSL in collaboration with scientific colleagues at Pacific Northwest National Laboratory. It will be housed in the Quiet Wing. To learn more about this system, the science it will advance and its historical development, visit the DTEM page.

Related information:

Instruments

EMSL's environmental transmission electron microscope (ETEM) is a state-of-the-art, Cs-corrected field emission gun (FEG) scanning transmission...
Custodian(s): Libor Kovarik
Type of Instrument:
Microscope
The Helium Ion Microscope promises to advance biological, geochemical, biogeochemical, and surface/interface studies using its combined surface...
The JEOL JEM-3000SFF was designed for high-resolution cryogenic transmission electron microscopy (cryo-EM) of biological samples and expands EMSL/...
EMSL's ultra-high vacuum, low-temperature scanning probe microscope instrument, or UHV LT SPM, is the preeminent system dedicated to surface...
Custodian(s): Igor Lyubinetsky
EMSL's aberration-corrected Titan 80-300™ scanning/transmission electron microscope (S/TEM) provides high-resolution imaging with sub-angstrom...
Custodian(s): Chongmin Wang, Scott Lea

Science Highlights

Posted: August 17, 2015
The Science With increasing emphasis on sustainable energy sources, lipid-derived biofuels have been proposed as a promising substitute for fossil...
Posted: March 30, 2015
The Science Lipids derived from oil-rich microorganisms such as bacteria, yeast and microalgae offer a promising source of renewable fuels and...
Posted: March 24, 2015
To understand a lithium battery at the nanoscale, scientists with EMSL and other organizations at the Department of Energy’s Joint Center for Energy...
Posted: October 07, 2014
The Science Steam reforming is a method for converting biomass-derived light hydrocarbons and aromatics into a mixture of carbon monoxide and...
Posted: August 03, 2014
The Science Nanocatalysts consisting of two metals can offer superior performance compared with those made up of only one metal, so they are widely...

Instruments

There are no related projects at this time.

EMSL’s Quiet Wing supports a wide range of research areas, including climate, biological, environmental and energy systems, of importance to the Department of Energy. It is among the most advanced quiet laboratories in the world for high-resolution imaging capabilities.

The Quiet Wing is a unique research environment housing a suite of ultrasensitive microscopy and scanning instruments. It was designed to help accelerate critical science by allowing state-of-the-art ultrasensitive microscopy equipment to operate at optimal resolution. A temperature-controlled facility, the wing’s design eliminates or reduces to a minimum the vibrations, acoustics and electromagnetic noise that can interfere with the resolution of ultrasensitive scientific instrumentation.

The 9,500-square-foot facility features eight quiet laboratory cells and a sample preparation area. The wing currently houses seven microscopy instruments and has room for one more. These microscopes are just a few of the extensive suite of microscopy instruments at EMSL available for scientific inquiry.

EMSL's microscopy capabilities, including those in the Quiet Wing, are available to the scientific community at typically no cost for openly published research. Scientists gain access to instruments and collaborate with onsite microscopy experts through a peer-reviewed proposal process. Learn more about becoming an EMSL user.

Learn more about each instrument and the science it advances on EMSL's YouTube channel and watch the video below on the Quiet Wing.

A new DTEM – Dynamic Transmission Electron Microscope – is under development at EMSL in collaboration with scientific colleagues at Pacific Northwest National Laboratory. It will be housed in the Quiet Wing. To learn more about this system, the science it will advance and its historical development, visit the DTEM page.

Related information:

1H NMR Metabolomics Study of Metastatic Melanoma in C57BL/6J Mouse Spleen.

Abstract: 

Melanoma is a malignant tumor of melanocytes. Although extensive investigations have been done to study metabolic changes in primary melanoma in vivo and in vitro, little effort has been devoted to metabolic profiling of metastatic tumors in organs other than lymph nodes. In this work, NMR-based metabolomics combined with multivariate data analysis is used to study metastatic B16-F10 melanoma in C57BL/6J mouse spleen. Principal Component Analysis (PCA), an unsupervised multivariate data analysis method, is used to detect possible outliers, while Orthogonal Projection to Latent Structure (OPLS), a supervised multivariate data analysis method, is employed to find important metabolites responsible for discriminating the control and the melanoma groups. Two different strategies, i.e., spectral binning and spectral deconvolution, are used to reduce the original spectral data before statistical analysis. Spectral deconvolution is found to be superior for identifying a set of discriminatory metabolites between the control and the melanoma groups, especially when the sample size is small. OPLS results show that the melanoma group can be well separated from its control group. It is found that taurine, glutamate, aspartate, O-Phosphoethanolamine, niacinamide ,ATP, lipids and glycerol derivatives are decreased statistically and significantly while alanine, malate, xanthine, histamine, dCTP, GTP, thymidine, 2'-Deoxyguanosine are statistically and significantly elevated. These significantly changed metabolites are associated with multiple biological pathways and may be potential biomarkers for metastatic melanoma in spleen.

Citation: 
Wang X, MY Hu, J Feng, M Liu, and JZ Hu.2014."1H NMR Metabolomics Study of Metastatic Melanoma in C57BL/6J Mouse Spleen."Metabolomics 10(6):1129-1144. doi:10.1007/s11306-014-0652-z
Authors: 
X Wang
MY Hu
J Feng
M Liu
JZ Hu
Volume: 
10
Issue: 
6
Pages: 
1129-1144
Publication year: 
2014

ToF-SIMS Depth Profiling Of Insulating Samples, Interlaced Mode Or Non-interlaced Mode?

Abstract: 

Dual beam depth profiling strategy has been widely adopted in ToF-SIMS depth profiling, in which two basic operation modes, interlaced mode and non-interlaced mode, are commonly used. Generally, interlaced mode is recommended for conductive or semi-conductive samples, whereas non-interlaced mode is recommended for insulating samples, where charge compensation can be an issue. Recent publications, however, show that the interlaced mode can be used effectively for glass depth profiling, despite the fact that glass is an insulator. In this study, we provide a simple guide for choosing between interlaced mode and non-interlaced mode for insulator depth profiling. Two representative cases are presented: (1) depth profiling of a leached glass sample, and (2) depth profiling of a single crystal MgO sample. In brief, the interlaced mode should be attempted first, because (1) it may provide reasonable-quality data, and (2) it is time-saving for most cases, and (3) it introduces low H/C/O background. If data quality is the top priority and measurement time is flexible, non-interlaced mode is recommended because interlaced mode may suffer from low signal intensity and poor mass resolution. A big challenge is tracking trace H/C/O in a highly insulating sample (e.g., MgO), because non-interlaced mode may introduce strong H/C/O background but interlaced mode may suffer from low signal intensity. Meanwhile, a C or Au coating is found to be very effective to improve the signal intensity. Surprisingly, the best analyzing location is not on the C or Au coating, but at the edge (outside) of the coating.

Citation: 
Wang Z, K Jin, Y Zhang, F Wang, and Z Zhu.2014."ToF-SIMS Depth Profiling Of Insulating Samples, Interlaced Mode Or Non-interlaced Mode?"Surface and Interface Analysis 46(S1):257-260. doi:10.1002/sia.5419
Authors: 
Z Wang
K Jin
Y Zhang
F Wang
Z Zhu
Volume: 
46
Issue: 
0
Pages: 
257-260
Publication year: 
2014

Microstructure of Multistage Annealed Nanocrystalline SmCo2Fe2B Alloy with Enhanced Magnetic Properties.

Abstract: 

The microstructure and chemistry of SmCo2Fe2B melt-spun alloy after multistage annealing was investigated using high resolution transmission electron microscopy (HRTEM) and 3D atom probe tomography. The multistage annealing resulted in an increase in both the coercivity and magnetization. The presence of Sm(Co,Fe)4B (1:4:1) and Sm2(Co,Fe)17Bx (2:17:x) magnetic phases were confirmed using both techniques. Fe2B at a scale of ∼5 nm was found by HRTEM precipitating within the 1:4:1 phase after the second-stage annealing. Ordering within the 2:17:x phase was directly identified both by the presence of antiphase boundaries observed by TEM and the interconnected isocomposition surface network found in 3D atom probe results in addition to radial distribution function analysis. The variations in the local chemistry after the secondary annealing were considered pivotal in improving the magnetic properties.

Citation: 
Jiang X, A Devaraj, B Balamurugan, J Cui, and JE Shield.2014."Microstructure of Multistage Annealed Nanocrystalline SmCo2Fe2B Alloy with Enhanced Magnetic Properties."Journal of Applied Physics 115(6):Article No. 063902. doi:10.1063/1.4865298
Authors: 
X Jiang
A Devaraj
B Balamurugan
J Cui
JE Shield
Volume: 
0
Issue: 
0
Pages: 
0
Publication year: 
2014

In Situ Study of CO2 and H2O Partitioning Between Na-Montmorillonite and Variably Wet Supercritical Carbon Dioxide.

Abstract: 

Shale formations play fundamental roles in large-scale geologic carbon sequestration (GCS) aimed primarily to mitigate climate change, and in smaller-scale GCS targeted mainly for CO2-enhanced gas recovery operations. In both technologies, CO2 is injected underground as a supercritical fluid (scCO2), where interactions with shale minerals could influence successful GCS implementation. Reactive components of shales include expandable clays, such as montmorillonites and mixed-layer illite/smectite clays. In this work, we used in situ X-ray diffraction (XRD) and in situ infrared (IR) spectroscopy to investigate the swelling/shrinkage and water/CO2 sorption of a pure montmorillonite, Na-SWy-2, when the clay is exposed to variably hydrated scCO2 at 50 °C and 90 bar. Measured interlayer spacings and sorbed water concentrations at varying levels of scCO2 hydration are similar to previously reported values measured in air at ambient pressure over a range of relative humidities. IR spectra show evidence of both water and CO2 intercalation, and variations in peak shapes and positions suggest multiple sorbed types with distinct chemical environments. Based on the intensity of the asymmetric CO stretching band of the CO2 associated with the Na-SWy-2, we observed a significant increase in sorbed CO2 as the clay expands from a 0W to a 1W state, suggesting that water props open the interlayer so that CO2 can enter. However, as the clay transitions from a 1W to a 2W state, CO2 desorbs sharply. These observations were placed in the context of two conceptual models concerning hydration mechanisms for expandable clays and were also discussed in light of recent theoretical studies on CO2-H2O-clay interactions. The swelling/shrinkage of expandable clays could affect solid volume, porosity, and permeability of shales. Consequently, the results from this work could aid predictions of shale caprock integrity in large-scale GCS, as well as methane transmissivity in enhanced gas recovery operations.

Citation: 
Loring JS, ES Ilton, J Chen, CJ Thompson, PF Martin, P Benezeth, KM Rosso, AR Felmy, and HT Schaef.2014."In Situ Study of CO2 and H2O Partitioning Between Na-Montmorillonite and Variably Wet Supercritical Carbon Dioxide."Langmuir 30(21):6120-6128. doi:10.1021/la500682t
Authors: 
JS Loring
ES Ilton
J Chen
CJ Thompson
PF Martin
P Benezeth
KM Rosso
AR Felmy
HT Schaef
Volume: 
30
Issue: 
21
Pages: 
6120-6128
Publication year: 
2014

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