Science around the Sound
April 26, 2013 at Pacific Northwest National Laboratory in Seattle, Wash.
Science around the Sound is an EMSL-sponsored seminar series designed to catalyze conversation about scientific advances among government, industry and academic researchers in Washington state.
Date: April 26,2013
Time: 3 - 4:30p.m., with a reception until 6p.m.
Location: Pacific Northwest National Laboratory, Seattle Research Center, 1100 Dexter Ave. N., Suite 400, Seattle (parking included)
Please arrive 15 minutes early to receive you access badge.
Register to reserve your spot by April 25, 2013.
Inaugural seminar presentation features:
"Design of New Protein Therapeutics and Nanomaterials" - David Baker
The exquisite functions of naturally occurring proteins solve the challenges confronting biological evolution. Humans face challenges today they did not face during natural evolution. I will describe our efforts to design a new generation of synthetic proteins to address these challenges.
Dr. Baker is Professor of Biochemistry and adjunct professor of Genome Sciences, Bioengineering, Chemical Engineering, Computer Science, and Physics at the University of Washington and an Investigator of the Howard Hughes Medical Institute. He received his Ph.D. degree in biochemistry with Randy Schekman at the University of California, Berkeley and did postdoctoral work in biophysics with David Agard at UCSF. His research group is focused on the prediction and design of macromolecular structures, interactions and functions. For more information on his numerous awards and honors, visit his web page.
"Dynamic TEM and Ultrafast X-ray Diffraction: New Methods for Visualizing Protein Structural Dynamics" - James Evans
Biologists have long strived to link macromolecular structure to physiological function and dynamics. This talk will discuss current progress and future applications of in situ liquid transmission electron microscopy (TEM), Dynamic TEM and ultrafast x-ray diffraction for imaging macromolecular processes (such as conformational switching and ligand binding) on the microsecond to femtosecond timescale with nanometer to angstrom spatial resolution.
Dr. Evans is a Staff Scientist with EMSL, a Department of Energy national scientific user facility located at Pacific Northwest National Laboratory. He obtained his PhD in Biochemistry and Molecular Biology from the University of California, Davis. His research interests include observing protein structure and dynamics in real-time and interrogating the interface of biology and nanotechnology using: aberration-corrected cryo-TEM, in situ TEM, Dynamic TEM, ultrafast x-ray diffraction, electron crystallography and electron and x-ray tomography.