Patrick El-Khoury | Environmental Molecular Sciences Laboratory

Novel Multimodal Chemical Nano-Imaging Approach to Visualize and Identify Small Biomolecules Exchanged in Microbial Communities

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Scott Lea

The ability to chemically visualize biological systems and processes on the nanometer length scale under relevant physiological conditions is an unmet need that if realized would revolutionize our…

Raman, Photoemission Electron Microscopy and Laser Desorption of Plasmonic Metal Nanostructures and Hybrid Metal - Insulator Photoemitters

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Patrick El-Khoury

The goal of this proposal is to measure structurally-dependent electronic bulk and surface dynamics of electrons, holes, and excitons, on different but well-characterized hybrid materials, using…

Multimodal Chemical Imaging Across Scales to Visualize Metabolic Pathways in Live Plants and Microbial Systems

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Scott Lea

We will develop a novel spectral imaging platform (“BioImager”) that may be used to image and identify biomolecules involved in both microbial and plant metabolic processes through different chemical…

Investigations on Electrode/Electrolyte Interfacial Reactions in Localized High-Concentration Electrolytes for Various Energy Storage Chemistries

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Mark Engelhard

Localized high-concentration electrolytes (LHCEs) developed at PNNL in 2017 for rechargeable lithium (Li) metal batteries show not only significant enhancement in protection of Li metal anode and…

Laser Desorption from Metal Oxides and Two-photon Photoemission Electron Microscopy

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wayne Hess

Laser interactions with nominally transparent (wide bandgap) materials are playing increasingly important roles in several technologies and applications, including chemical analysis, semiconductor…

Multimodal Chemical Imaging Across Scales to Visualize Metabolic Pathways in Live Plants and Microbial Systems

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Scott Lea

We will develop a novel spectral imaging platform (“BioImager”) that may be used to image and identify biomolecules involved in both microbial and plant metabolic processes through different chemical…

Advanced High Resolution and Dynamic in-situ TEM/STEM Observations of Materials Processes

Lead Institution

University of Liverpool

Principal Investigator

Nigel Browning

The first goal of this research program is to develop a robust method to quantify the atomic scale changes in structure, composition and bonding that occur at interfaces under a variety of…

Influence of Phase-Changing Medium on Surface-Enhanced Electromagnetic Fields and Coherence Lifetime of Active Plasmonic Nanostructures

Lead Institution

Vanderbilt University

Principal Investigator

Richard Haglund

Project type

Large-Scale EMSL Research

The miniaturization of photonic circuits is critical to 21st century data processing and telecommunication technologies. Plasmonics, based on the optical properties of metallic nanostructures, holds…

Light Source Photocathode Performance and Development

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wayne Hess

Accelerator photocathode technology must be advanced to meet the needs of fourth generation light sources. The ultimate output characteristics and cost of next generation UV or X-ray sources, whether…

Modeling valence and core-level spectra of molecules and materials via linear-response and real-time TDDFT

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Niranjan Govind

This is a three-pronged proposal aimed to address valence and core-level excited state properties in molecules and materials using linear-response and real-time TDDFT. This effort will be a…

High-Resolution Sum-Frequency Generation Vibrational Spectroscopy
Capability Development Project WBS

Lead Institution

Fudan University

Principal Investigator

Hongfei Wang

The objective of this WBS element is to further develop experimental and user service capability to perform surface nonlinear spectroscopy and dynamics measurements with both high spectral resolution…

Laser Desorption, Raman, Photoemission and Electron Microscopy of Hybrid Metal - Insulator Nanostructures

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wayne Hess

The details of how photons couple to wide bandgap materials and the consequences of these excitations such as particle emission and field enhancement are playing increasingly important roles in…

Advanced High Resolution and Dynamic in-situ TEM/STEM Observations of Materials Processes

Lead Institution

University of Liverpool

Principal Investigator

Nigel Browning

The first goal of this research program is to develop a robust method to quantify the atomic scale changes in structure, composition and bonding that occur at interfaces under a variety of…

Molecular Mechanisms Underlying Nanomaterial Toxicity or Biocompatibility

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Galya Orr

This proposal covers research conducted with funding from several agencies, including NIEHS and the NSF-funded Center for Sustainable Nanotechnology. The rapid growth in nanotechnology is expected to…

Raman, Photoemission Electron Microscopy and Laser Desorption of Plasmonic Metal Nanostructures

and Hybrid Metal - Insulator Photoemitters

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wayne Hess

The goal of this proposal is to measure structurally-dependent electronic bulk and surface dynamics of electrons, holes, and excitons, on different but well-characterized hybrid materials, using…

Multimodal Nanoscale Chemical Imaging of Intra- and Inter-Cellular Biomolecules Involved in Microbial Interactions

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Scott Lea

Microbes orchestrate a suite of intra- and inter-cellular biomolecules to carry out diverse metabolic processes. Existing genomic and biochemical methods cannot directly probe the physical…

Benchmark studies of non-covalent interactions

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Edoardo Apra

Non-covalent interactions have manifested their importance as the dominant types of interactions that control supramolecular chemistry with applications in molecular self-assembly, folding, molecular…

Multimodal Nanoscale Chemical Imaging of Intra- and Inter-Cellular Biomolecules Involved in Microbial Interactions

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Scott Lea

Microbes orchestrate a suite of intra- and inter-cellular biomolecules to carry out diverse metabolic processes. Existing genomic and biochemical methods cannot directly probe the physical…

Projects