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Justin Teeguarden
Chief Science Officer

Justin Teeguarden is a Pacific Northwest National Laboratory (PNNL) Fellow and EMSL’s Chief Science Officer. With over 20 years of scientific leadership as a computational and experimental scientist, Teeguarden leads EMSL's strategic science planning and internal R&D initiatives. He currently serves as vice-chair of the U.S. Environmental Protection Agency’s (EPA) Board of Scientific Counselors Homeland Security Subcommittee, as PNNL’s representative to the Indo Pacific Research Alliance for Military Medicine, and he holds a joint appointment with the Department of Environmental and Molecular Toxicology at Oregon State University (OSU) where he is the principal investigator on the PNNL-OSU National Institutes of Health Superfund research program. Teeguarden has served on multiple National Academy of Sciences (NAS) Committees, and his various roles are a result of extensive experience in computational modeling, toxicology, and exposure science.

Education

  • PhD in Toxicology, University of Wisconsin-Madison, 1999
  • BS in Biochemistry, University of California, Davis, 1990

Affiliations and Professional Service

  • Chair, NAS Committee to review the U.S. Department of Defense physiologically based pharmacokinetic model for establishing occupational exposure limits for lead exposure (2019 – 2020)
  • Homeland Security Subcommittee, U.S. EPA Board of Scientific Councilors (2018 – Present)
  • Editorial Board, Computational Toxicology (2016 – Present)            
  • Member, NAS Committee on Incorporating 21st Century Science into Risk Based Decisions (2015 – 2017)
  • Editorial Board, Journal of Exposure Science and Environmental Epidemiology (2014 – Present)
  • Committee on Contemporary Concepts in Toxicology, Society of Toxicology (SOT) (2012)
  • Member, NAS Committee on Exposure Science in the 21st Century (2011 – 2012)
  • President, Nanotoxicology Specialty Section, SOT (2011 – 2012)
  • Associate Editor, Nanotoxicology (2011 – Present)
  • Board of Scientific Counselors, National Toxicology Program (2009 – 2011)
  • Councilor, Biological Modeling Specialty Section, SOT (2008 – 2009)
  • Chair, Dose-Response Specialty Group, Society of Risk Analysis (2004 – 2006)
  • Diplomate, American Board of Toxicology (2002 – Present)
  • Vice-Chair, Board of Scientific Counselors Homeland Security Subcommittee, U.S. EPA
  • Representative, Indo Pacific Research Alliance for Military Medicine
  • Joint Appointment, Department of Environmental and Molecular Toxicology, OSU
  • National Academies of Sciences committees
  • Secretary, Research Triangle Chapter, Society of Risk Analysis (2000 – 2001)

Publications

2019

Colby S.M., D.G. Thomas, J. Nunez, D.J. Baxter, K.R. Glaesemann, J.M. Brown, and M.A. Pirrung, et al. 2019. "ISiCLE: A Quantum Chemistry Pipeline for Establishing in Silico Collision Cross Section Libraries." Analytical Chemistry 91, no. 7:4346-4356. PNNL-SA-138476. doi:10.1021/acs.analchem.8b04567

Pande P., S.C. Fleck, N.C. Twaddle, M.I. Churchwell, D.R. Doerge, and J.G. Teeguarden. 2019. "Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women II: Total estrogenicity calculations accounting for competitive protein and receptor binding and potency." Food and Chemical Toxicology 125. PNNL-ACT-SA-10390. doi:10.1016/j.fct.2018.12.013

Septiadi D., L. Rodriguez-Lorenzon, S. Balog, M. Spuch-Calvar, G. Spiaggia, P. Taladriz-Blanco, and H. Barosova, et al. 2019. "Quantification of Carbon Nanotube Doses in Adherent Cell Culture Assays Using UV-VIS-NIR Spectroscopy." Nanomaterials 9, no. 12:1765. PNNL-SA-150718. doi:10.3390/nano9121765

Thrall B.D., V.K. Kodali, S.J. Skerret, S.J. Skerret, D.G. Thomas, C. Frevert, and J.G. Pounds, et al. 2019. "Modulation of susceptibility to lung bacterial infection by engineered nanomaterials: In vitro and in vivo correspondence based on macrophage phagocytic function." NanoImpact 14. PNNL-SA-128523. doi:10.1016/j.impact.2019.100155

2018

Fantke P., L.L. Aylward, J. Bare, W. Chiu, R. Dodson, R. Dwyer, and A. Ernstoff, et al. 2018. "Advancements in Life Cycle Human Exposure and Toxicity Characterization." Environmental Health Perspectives 126, no. 12:CID: 125001. PNNL-SA-148788. doi:10.1289/EHP3871

Fleck S.C., N.C. Twaddle, M.I. Churchwell, D.R. Doerge, P. Pande, and J.G. Teeguarden. 2018. "Comparative Extrogenicity of Endogenous, Environmental and Dietary Estrogens in Pregnant Women I: Serum Levels, Variability and the Basis for Urinary Biomonitoring of Serum Estrogenicity." Food and Chemical Toxicology 115. PNNL-ACT-SA-10289. doi:10.1016/j.fct.2018.03.017

Geier M., D. Minick, L. Truong, S.C. Tilton, P. Pande, K. Anderson, and J.G. Teeguarden, et al. 2018. "Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish." Toxicology and Applied Pharmacology 354. PNNL-SA-144343. doi:10.1016/j.taap.2018.03.029

Smith J.N., D.G. Thomas, H.D. Jolley, V.K. Kodali, M.H. Littke, P. Munusamy, and D.R. Baer, et al. 2018. "All that is Silver is not Toxic: Silver Ion and Particle Kinetics Reveals the Role of Silver Ion Aging and Dosimetry on the Toxicity of Silver Nanoparticles." Particle and Fibre Toxicology 15. PNNL-SA-135829. doi:10.1186/s12989-018-0283-z

Tan Y., J.A. Leonard, S. Edwards, J.G. Teeguarden, and P. Egeghy. 2018. "Refining the aggregate exposure pathway." Environmental Science: Processes & Impacts 20, no. 3:428-436. PNNL-SA-137436. doi:10.1039/C8EM00018B

Thomas D.G., J.N. Smith, B.D. Thrall, D.R. Baer, H.D. Jolley, P. Munusamy, and V.K. Kodali, et al. 2018. "ISD3: A Particokinetic Model for Predicting the Combined Effects of Particle Sedimentation, Diffusion and Dissolution on Cellular Dosimetry for In Vitro Systems." Particle and Fibre Toxicology 15. PNNL-SA-125563. doi:10.1186/s12989-018-0243-7

Yesiltepe Y., J. Nunez, S.M. Colby, D.G. Thomas, M.I. Borkum, P.N. Reardon, and N.M. Washton, et al. 2018. "An automated framework for NMR chemical shift calculations of small organic molecules." Journal of Cheminformatics 10. PNNL-SA-137588. doi:10.1186/s13321-018-0305-8

2017

Davie-Martin C.L., K.G. Stratton, J.G. Teeguarden, K.M. Waters, and S.L. Massey Simonich. 2017. "Implications of bioremediation of polycyclic aromatic hydrocarbon-contaminated soils for human health and cancer risk." Environmental Science & Technology 51, no. 17:9458-9468. PNNL-SA-122323. doi:10.1021/acs.est.7b02956

Knecht A., L. Truong, S.W. Marvel, D. Reif, A. Garcia, C. Lu, and M. Simonich, et al. 2017. "Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish." Toxicology and Applied Pharmacology 329. PNNL-SA-127160. doi:10.1016/j.taap.2017.05.033

Ma J., C.P. Casey, X. Zheng, Y.M. Ibrahim, C.S. Wilkins, R.S. Renslow, and D.G. Thomas, et al. 2017. "PIXiE: An Algorithm for Automated Ion Mobility Arrival Time Extraction and Collision Cross Section Calculation using Global Data Association." Bioinformatics 33, no. 17:2715-2722. PNNL-SA-122828. doi:10.1093/bioinformatics/btx305

Metz T.O., E.M. Baker, E.L. Schymanski, R.S. Renslow, D.G. Thomas, T.J. Causon, and I.K. Webb, et al. 2017. "Integrating Ion Mobility Spectrometry into Mass Spectrometry-based Exposome Measurements: What Can It Add and How Far Can It Go?." Bioanalysis 9, no. 1:81-98. PNNL-SA-121158. doi:10.4155/bio-2016-0244

2016

Kabilan S., S.R. Suffield, K.P. Recknagle, R.E. Jacob, D.R. Einstein, A.P. Kuprat, and J.P. Carson, et al. 2016. "Computational Fluid Dynamics Modeling of Bacillus anthracis Spore Deposition in Rabbit and Human Respiratory Airways." Journal of Aerosol Science 99. PNNL-SA-108616. doi:10.1016/j.jaerosci.2016.01.011

Teeguarden J.G., N.C. Twaddle, M.I. Churchwell, and D.R. Doerge. 2016. "Urine and serum biomonitoring of exposure to environmental estrogens I: Bisphenol A in pregnant women." Food and Chemical Toxicology 92. PNNL-ACT-SA-10170. doi:10.1016/j.fct.2016.03.023

Teeguarden J.G., Y. Tan, S. Edwards, J.A. Leonard, K. Anderson, R.A. Corley, and M.L. Kile, et al. 2016. "Expanding on Successful Concepts, Models, and Organization." Environmental Science & Technology 50, no. 17:8921-8922. PNNL-SA-119240. doi:10.1021/acs.est.6b03027

Teeguarden J.G., Y. Tan, Y. Tan, S. Edwards, J.A. Leonard, K.A. Anderson, and R.A. Corley, et al. 2016. "Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework." Environmental Science & Technology 50, no. 9:4579-4586. PNNL-SA-114098. doi:10.1021/acs.est.5b05311

Zhang X., M.V. Romm, X. Zheng, E.M. Zink, Y. Kim, K.E. Burnum-Johnson, and D.J. Orton, et al. 2016. "SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in bio?uids." Clinical Mass Spectrometry 2. PNNL-SA-117436. doi:10.1016/j.clinms.2016.11.002

2015

Corley R.A., S. Kabilan, A.P. Kuprat, J.P. Carson, R.E. Jacob, K.R. Minard, and J.G. Teeguarden, et al. 2015. "COMPARATIVE RISKS OF ALDEHYDE CONSTITUENTS IN CIGARETTE SMOKE USING TRANSIENT COMPUTATIONAL FLUID DYNAMICS/PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS OF THE RAT AND HUMAN RESPIRATORY TRACTS." Toxicological Sciences 146, no. 1:65-88. PNNL-SA-106531. doi:10.1093/toxsci/kfv071

Teeguarden J.G., N.C. Twaddle, M.I. Churchwell, X. Yang, J. Fisher, L.M. Seryak, and D.R. Doerge. 2015. "24-Hour Human Urine and Serum Profiles of Bisphenol A: Evidence against Sublingual Absorption Following Ingestion in Soup." Toxicology and Applied Pharmacology 288, no. 2:131-142. PNNL-ACT-SA-10045. doi:10.1016/j.taap.2015.01.009

Teeguarden J.G., N.C. Twaddle, M.I. Churchwell, X. Yang, J.W. Fisher, L.M. Seryak, and D.R. Doerge. 2015. "24-Hour Human Urine and Serum Profiles of Bisphenol A Following Ingestion in Soup: Individual Pharmacokinetic Data and Demographics." Data in Brief 4. PNNL-ACT-SA-10050. doi:10.1016/j.dib.2015.03.002

Yang X., D.R. Doerge, J.G. Teeguarden, and J.W. Fisher. 2015. "Development of a physiologically based pharmacokinetic model for assessment of human exposure to bisphenol A." Toxicology and Applied Pharmacology 289, no. 3:442-456. PNNL-ACT-SA-10135. doi:10.1016/j.taap.2015.10.016

2014

Asgharian B., O. Price, M. Oldham, L. Chen, E.L. Saunders, T. Gordon, and V.B. Mikheev, et al. 2014. "Computational modeling of nanoscale and microscale particle deposition, retention and dosimetry in the mouse respiratory tract." Inhalation Toxicology 26, no. 14:829-842. PNNL-SA-109668. doi:10.3109/08958378.2014.935535

Cohen J., J.G. Teeguarden, and P. Demokritou. 2014. "An integrated approach for the in vitro dosimetry of engineered nanomaterials." Particle and Fibre Toxicology 11. PNNL-SA-106412. doi:10.1186/1743-8977-11-20

LaKind J.S., J.R. Sobus, M. Goodman, D.B. Barr, P. Furst, R.J. Albertini, and T.E. Arbuckle, et al. 2014. "A Proposal for Assessing Study Quality: Biomonitoring, Environmental Epidemiology, and Short-Lived Chemicals (BEES-C) Instrument." Environment International 73. PNWD-SA-10307. doi:10.1016/j.envint.2014.07.011

Larson J.K., M.J. Carvan, J.G. Teeguarden, G. Watanabe, K. Taya, E. Krystofiak, and R.J. Hutz. 2014. "Low-dose gold nanoparticles exert subtle endocrine-modulating effects on the ovarian steroidogenic pathway ex vivo independent of oxidative stress." Nanotoxicology 8, no. 8:856-66. PNNL-SA-101177. doi:10.3109/17435390.2013.837208

Teeguarden J.G., V.B. Mikheev, K.R. Minard, W.C. Forsythe, W. Wang, G. Sharma, and N.J. Karin, et al. 2014. "Comparative Iron Oxide Nanoparticle Cellular Dosimetry and Response in Mice by the Inhalation and Liquid Cell Culture Exposure Routes." Particle and Fibre Toxicology 11. PNNL-SA-101188. doi:10.1186/s12989-014-0046-4

2013

DeWoskin R.D., L.M. Sweeney, J.G. Teeguarden, R. Sams, and J. Vandenberg. 2013. "Comparison of PBTK Model and Biomarker Based Estimates of the Internal Dosimetry of Acrylamide." Food and Chemical Toxicology 58. PNWD-SA-9921. doi:10.1016/j.fct.2013.05.008

Kodali V.K., M.H. Littke, S.C. Tilton, J.G. Teeguarden, L. Shi, C.W. Frevert, and W. Wang, et al. 2013. "Dysregulation of Macrophage Activation Profiles by Engineered Nanoparticles." ACS Nano 7, no. 8:6997-7010. PNNL-SA-95359. doi:10.1021/nn402145t

Minard K.R., M.H. Littke, W. Wang, Y. Xiong, J.G. Teeguarden, and B.D. Thrall. 2013. "Magnetic Particle Detection (MPD) for In-Vitro Dosimetry." Biosensors and Bioelectronics 43. PNNL-SA-90647. doi:10.1016/j.bios.2012.12.011

Shankaran H., F. Adeshina, and J.G. Teeguarden. 2013. "Physiologically-Based Pharmacokinetic Model for Fentanyl in Support of the Development of Provisional Advisory Levels." Toxicology and Applied Pharmacology 273, no. 13:002464-476. PNWD-SA-10008. doi:10.1016/j.taap.2013.05.024

Sharma G., V.K. Kodali, M.J. Gaffrey, W. Wang, K.R. Minard, N.J. Karin, and J.G. Teeguarden, et al. 2013. "Iron Oxide Nanoparticle Agglomeration Influences Dose-Rates and Modulates Oxidative Stress Mediated Dose-Response Profiles In Vitro." Nanotoxicology 8, no. 6:663-675. PNNL-SA-93447. doi:10.3109/17435390.2013.822115

Teeguarden J.G., and S. Hanson-Drury. 2013. "A Systematic Review of Bisphenol A “Low Dose” Studies in the Context of Human Exposure: A Case for Establishing Standards for Reporting “Low- Dose” Effects of Chemicals." Food and Chemical Toxicology 62. PNWD-SA-10180. doi:10.1016/j.fct.2013.07.007

Teeguarden J.G., C. Housand, J.N. Smith, P.M. Hinderliter, R. Gunawan, and C. Timchalk. 2013. "A Multi-Route Model of Nicotine-Cotinine Pharmacokinetics, Pharmacodynamics and Brain Nicotinic Acetylcholine Receptor Binding in Humans." Regulatory Toxicology and Pharmacology 65, no. 1:12-28. PNNL-SA-92151. doi:10.1016/J.YRTPH.2012.10.007

Teeguarden J.G., J. Fisher, and D.R. Doerge. 2013. "Exposure Conditions and Pharmacokinetic Principles: Interpreting Bisphenol A Absorption in the Canine Oral Cavity." Environmental Health Perspectives 121, no. 11-12:A323-A323. PNWD-SA-10183. doi:10.1289/ehp.1307424

Teeguarden J.G., S. Hanson-Drury, J.W. Fisher, and D.R. Doerge. 2013. "Are Typical Human Serum BPA Concentrations Measureable and Sufficient to be Estrogenic in the General Population?." Food and Chemical Toxicology 62. PNWD-SA-10192. doi:10.1016/j.fct.2013.08.001

2012

Karakoti A.S., P. Munusamy, K.E. Hostetler, V.K. Kodali, S.N. Kuchibhatla, G. Orr, and J.G. Pounds, et al. 2012. "Preparation and Characterization Challenges to Understanding Environmental and Biological Impacts of Ceria Nanoparticles." Surface and Interface Analysis 44, no. 8:881-889. PNNL-SA-83765. doi:10.1002/sia.5006

Teeguarden J.G., A. Calafat, and D.R. Doerge. 2012. "Adhering to Fundamental Principles of Biomonitoring, BPA Pharmacokinetics, and Mass Balance is no "Flaw"." Toxicological Sciences 125, no. 1:321-325. PNWD-SA-9573. doi:10.1093/toxsci/kfr275

Thrall B.D., K.R. Minard, J.G. Teeguarden, and K.M. Waters. 2012. Multiscale Toxicology - Building the Next Generation Tools for Toxicology. PNNL-21916. Richland, WA: Pacific Northwest National Laboratory. Multiscale Toxicology - Building the Next Generation Tools for Toxicology

Xie Y., N.G. Williams, A. Tolic, W.B. Chrisler, J.G. Teeguarden, B.L. Maddux, and J.G. Pounds, et al. 2012. "Aerosolized ZnO nanoparticles induce toxicity in alveolar type II epithelial cells at the air-liquid interface." Toxicological Sciences 125, no. 2:450-461. PNNL-SA-83610. doi:10.1093/toxsci/kfr251

2011

Baer D.R., A.S. Karakoti, P. Munusamy, B.D. Thrall, J.G. Pounds, J.G. Teeguarden, and J.E. Amonette, et al. 2011. "Testing in EHS: What is the Current Status of Experimentation?." In 11th IEEE International Conference on Nanotechnology (IEEE-NANO 2011), August 15-18, 2011, Portland, Oregon, 18-19. Piscataway, New Jersey:IEEE. PNNL-SA-90027. doi:10.1109/NANO.2011.6144671

Paur H., F.R. Cassee, J.G. Teeguarden, H. Fissan, S. Diabate, M. Aufderheide, and W.G. Kreyling, et al. 2011. "In-vitro Cell Exposure Studies for the Assessment of Nanoparticle Toxicity in the Lung - A Dialogue between Aerosol Science and Biology." Journal of Aerosol Science 42, no. 10:668-692. PNNL-SA-75727. doi:10.1016/j.jaerosci.2011.06.005

Teeguarden J.G., A. Calafat, X. Ye, D.R. Doerge, M.I. Churchwell, R. Gunawan, and M.K. Graham. 2011. "Twenty-Four Hour Human Urine and Serum Profiles of Bisphenol A during High-Dietary Exposure." Toxicological Sciences 123, no. 1:48-57. PNWD-SA-9583. doi:10.1093/toxsci/kfr160

Teeguarden J.G., B.M. Webb-Robertson, K.M. Waters, A. Murray, E. Kisin, S.M. Varnum, and J.M. Jacobs, et al. 2011. "Comparative Proteomics and Pulmonary Toxicity of Instilled Single Walled Carbon Nanotubes, Crocidolite Asbestos and Ultrafine Carbon Black in Mice." Toxicological Sciences 120, no. 1:123-135. PNNL-SA-74369. doi:10.1093/toxsci/kfq363

2010

Hinderliter P.M., K.R. Minard, G. Orr, W.B. Chrisler, B.D. Thrall, J.G. Pounds, and J.G. Teeguarden. 2010. "ISDD: A Computational Model of Particle Sedimentation, Diffusion and Target Cell Dosimetry for In Vitro Toxicity Studies." Particle and Fibre Toxicology 7, no. November:Article No. 36. PNNL-SA-74873. doi:10.1186/1743-8977-7-36

2009

Crump K.S., and J.G. Teeguarden. 2009. "Benchmark calculations from summarized data: an example." Environmental and Ecological Statistics 16, no. 1:13-24. PNNL-SA-62810.

Waters K.M., L.M. Masiello, R.C. Zangar, B.J. Tarasevich, N.J. Karin, R.D. Quesenberry, and S. Bandyopadhyay, et al. 2009. "Macrophage Responses to Silica Nanoparticles are Highly Conserved Across Particle Sizes." Toxicological Sciences 107, no. 2:553-569. PNNL-SA-62659.

2008

Dorman D.C., M.F. Struve, M.F. Struve, B.A. Wong, E.A. Gross, C. Parkinson, and G.A. Willson, et al. 2008. "Derivation of an Inhalation Reference Concentration Based Upon Olfactory Neuronal Loss in Male Rats Following Subchronic Acetaldehyde Inhalation." Inhalation Toxicology 20, no. 3:245-256. PNWD-SA-8184. doi:10.1080/08958370701864250

Nong A., J.G. Teeguarden, H.J. Clewell, III, D.C. Dorman, and M.E. Andersen. 2008. "Pharmacokinetic Modeling of Manganese in the Rat IV: Assessing Factors that Contribute to Brian Accumulation During Inhalation Exposure." Journal of Toxicology and Environmental Health Part A 71, no. 7:413-426. PNNL-SA-60107. doi:10.1080/15287390701838697

Teeguarden J.G., A. Gupta, P. Escobar, and M. Jackson. 2008. "Toxicology steps up to nanotechnology safety." Research & Development 50, no. 1:28-29. PNWD-SA-7902.

Teeguarden J.G., M.S. Bogdanffy, T.R. Covington, C. Tan, C. Tan, and A.M. Jarabek. 2008. "A PBPK Model for Evaluating the Impact of Aldehyde Dehydrogenase Polymorphisms on Comparative Rat and Human Nasal Tissue Acetaldehyde Dosimetry." Inhalation Toxicology 20, no. 4:375-390. PNWD-SA-8034. doi:10.1080/08958370801903750

2007

Dutta D., S.K. Sundaram, J.G. Teeguarden, B.J. Riley, L.S. Fifield, J.M. Jacobs, and R.S. Addleman, et al. 2007. "Adsorbed Proteins Influence the Biological Activity and Molecular Targeting of Nanomaterials." Toxicological Sciences 100, no. 1:303-315. PNNL-SA-55139. doi:10.1093/toxsci/kfm217

Orr G., D.J. Panther, J.L. Phillips, B.J. Tarasevich, A. Dohnalkova, D. Hu, and J.G. Teeguarden, et al. 2007. "Submicron and Nanoscale Inorganic Particles Exploit the Actin Machinery to be Propelled Along Microvillilike Structures into Alveolar Cells." ACS Nano 1, no. 5:463-475. PNNL-SA-53625. doi:10.1021/nn700149r

Teeguarden J.G., D.C. Dorman, A. Nong, T.R. Covington, H.J. Clewell, III, and M.E. Andersen. 2007. "Pharmacokinetic Modeling of Manganese II. Hepatic Processing after Ingestion and Inhalation." Journal of Toxicology and Environmental Health Part A 70, no. 18:1505-1514. PNWD-SA-7554. doi:10.1080/15287390701384619

Teeguarden J.G., D.C. Dorman, T.R. Covington, H.J. Clewell, III, and M.E. Andersen. 2007. "Pharmacokinetic Modeling of Manganese I. Dose-Dependencies of Uptake and Elimination." Journal of Toxicology and Environmental Health Part A 70, no. 18:1493-1504. PNWD-SA-7553. doi:10.1080/15287390701384601

Teeguarden J.G., J. Gearhart, H.J. Clewell, III, T.R. Covington, A. Nong, and M.E. Anderson. 2007. "Pharmacokinetic Modeling of Manganese III. Physiological Approaches Accounting for Background and Tracer Kinetics." Journal of Toxicology and Environmental Health Part A 70, no. 18:1515-1526. PNNL-SA-52194. doi:10.1080/15287390701384635

Teeguarden J.G., P.M. Hinderliter, G. Orr, B.D. Thrall, and J.G. Pounds. 2007. "Particokinetics In Vitro: Dosimetry Considerations for In Vitro Nanoparticle Toxicity Assessments." Toxicological Sciences 95, no. 2:300-312. PNNL-SA-55055. doi:10.1093/toxsci/kfl165

2005

Teeguarden J.G., J.M. Waechter, H.J. Clewell, III, T.R. Covington, and H.A. Barton. 2005. "Evaluation of Oral and IntravenousRoute Pharmacokinetics, Plasma Protein Binding and Uterine Tissue Dose Metrics of Bisphenol A: A Physiologically Based Pharmacokinetic Approach." Toxicological Sciences 85, no. 2:823-838. PNWD-SA-6845. doi:10.1093/toxsci/kfil135

Teeguarden J.G., P.J. Deisinger, T.S. Poet, J.C. English, W.D. Faber, H.A. Barton, and R.A. Corley, et al. 2005. "Derivation of a human equivalent concentration for n-butanol using a physiologically based pharmacokinetic model for n-butyl acetate and metabolites n-butanol and n-butyric acid." Toxicological Sciences 85, no. 1:429-446. PNNL-SA-42701.