Environmental Molecular Sciences Laboratory

A DOE Office of Science User Facility

This page lives in the old site. Check out our new site here.

Mass Spectrometer: 21T FTICR

EMSL’s 21 Tesla Fourier transform ion cyclotron resonance mass spectrometer, or 21T FTICR MS, is one of only two in the world with this high of a magnetic field strength. The 21T FTICR MS significantly enhances EMSL’s overall mass spectrometry analytical and characterization performance in terms of sensitivity, dynamic range, accuracy, resolution and speed.

This unprecedented level of performance is needed to unravel the chemistry and dynamics of complex natural systems in the environment. This transformative instrument enables the characterization of large, intact proteins and complex environmental and biological materials, allowing researchers to tackle previously intractable questions related to microbial communities, biofuel development, climate and environmental remediation.

By greatly advancing the molecular-level understanding of complex systems, this revolutionary mass spectrometry capability will enable better-informed technical and policy decisions affecting environmental remediation, waste processing, energy production and associated impacts to the environment. Moreover, the development of this mass spectrometry capability will ensure that EMSL will continue to provide leading-edge mass spectrometry resources to serve national and international users who are addressing critical Department of Energy mission needs. 

21T FTICR
The 21T FTICR mass spectrometer’s high field strength allows for higher resolution and higher mass accuracy measurements that ensure identification of molecular constituents in complex samples and materials.

Watch this video to learn how the 21T FTICR Mass Spectrometer can accelerate your research.

Malak Tfaily, 21 Tesla FTICR Mass Spectrometer

In the News

The impressive capabilities and promise of this next-generation instrument was highlighted in a feature article published Sept. 11, 2015, in Science. In the article, Ljiljana Paša-Tolić, EMSL’s lead scientist for mass spectrometry and technical lead for development of the 21T FTICR MS, explained the potential of using this instrument to characterize large, intact proteins in microbial communities or natural organic matter in soils and aerosols. Paša-Tolić was one of six scientists featured in the article.

Magnetic Attraction,” the cover story in the June issue of The Molecular Bond, EMSL’s bi-monthly newsletter, features the six inaugural studies selected to use the new instrument through a Special Science Call.

Instrument ID:
34225
Availability: 10 hours a day, 5 days a week

Custodians

Ljiljana Pasa Tolic (509) 371-6585 ljiljana.pasatolic@pnnl.gov
Mary Lipton (509) 371-6589 mary.lipton@pnnl.gov

Publications

Hypomyelination, a neurological disorder characterized by a decrease in the production of myelin sheets by glial cells, often has no known etiology....
The chemical speciation and bioavailability of mercury (Hg) is markedly influenced by its complexation with naturally dissolved organic matter (DOM)...
Biofilms are critical locations for biogeochemical reactions in the subsurface environment. The occurrence and distribution of biofilms at microscale...
Droughts and other extreme precipitation events are predicted to increase in intensity, duration and extent, with uncertain implications for...
Spatial isolation of soil organic carbon (SOC) in different sized pores may be a mechanism by which otherwise labile carbon (C) could be protected in...
Molecular composition of the Arctic soil organic carbon (SOC) and its susceptibility to microbial degradation are uncertain due to heterogeneity and...
Soil heterotrophic respiration (HR) is an important source of soil-to-atmosphere CO2 flux, but its response to changes in soil water content (?) is...
Motivation: Drift tube ion mobility spectrometry (DTIMS) is increasingly implemented in high throughput omics workflows, and new informatics...
The fungal kingdom is the source of almost all industrial enzymes in use for lignocellulose bioprocessing. Its more primitive members, however,...

Quick Specs

    • Cu x-ray tube operated at 40 kV and 15 mA (600W)
    • Bragg-Brentano geometry, fixed or variable+fixed slits
    • Graphite monochromator and scintillation detector
    • Vertical goniometer, 0 to 145 °2θ
    • Automated 6-position sample changer for powder specimens

Science Highlights

Posted: Thursday, January 24, 2019 - 11:45
The Science Important compounds called siderophores help bacteria and fungi scavenge essential nutrients like iron from the soil. But how the...
Posted: Monday, December 5, 2016 - 15:30
The Science A recent study demonstrated enormous potential for scientists to explore extremely complex molecular mixtures and systems frequently...
Posted: Tuesday, November 3, 2015 - 09:08
Achieving a holistic, molecular-level understanding of cellular machinery and communication, microbial community dynamics, and other interactions...

Projects

Enzymatic hydrolysis of (ligno)cellulose by cellulases is key for the production of second generation biofuels which represent a long-standing...
Peatlands store 1/3 of all soil carbon (C) and currently act as net C sinks sequestering C as a complex mixture of organic compounds. The anoxic,...
The abundances of naturally occurring rare stable isotopes (e.g., D, 13C, 15N, 18O) are widely used as constraints for problems concerned with the...
The proposed project will advance understanding of the response of methane production and methane oxidation to changes in plant productivity so that...
Lignin obtained from lignocellulosic biomass is an abundant, renewable, low-cost resource whose carbon-rich, aromatic composition makes it ideal to...