Environmental Molecular Sciences Laboratory

A DOE Office of Science User Facility

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User Projects

The following is a list of projects that have been active over the past three years.
For a comprehensive list of projects, see All Projects. You can also search for released data.
Lead Institution: Pacific Northwest National Laboratory
Principal Investigator: Dongsheng Li
The long-term goal of this project is to understand the growth of complex crystalline structures by aggregation and oriented attachment (OA) of primary nanoparticles and thus to tune crystal structures with desired properties. The formation of...
Lead Institution: Pacific Northwest National Laboratory
Principal Investigator: Dongsheng Li
Electrical, optical and mechanical properties of inorganic nanostructures have strong relationships with their morphologies. For example, one-dimensional (1D) nanomaterials such as carbon nanotubes, ZnO nanowires, TiO2 nanotubes possess novel...
Lead Institution: Environmental Molecular Sciences Laboratory
Principal Investigator: Ying Zhu
The project aims to develop a high throughput and multiplex affinity purification mass spectrometry (AP-MS) assay by seamless integration of protein microarray and nanoscale proteomics. We will immobilize SARS-COV-2 proteins on a glass slide by...
Lead Institution: Environmental Molecular Sciences Laboratory
Principal Investigator: Ying Zhu
The project aims to improve both sensitivity and throughput in single cell proteomics through the development of a microfluidic platform that leverages current technology. A hybrid picowell/nanowell chip will be designed and tested for single cell...
Lead Institution: Desert Research Institute
Principal Investigator: Rishi Parashar
Remediation of metal and radionuclide contaminants in soil and groundwater systems is challenging because of their strong chemical interactions with mineral surfaces and low concentration limits for human health requirements. In situ bioremediation...
Lead Institution: Pacific Northwest National Laboratory
Principal Investigator: Jason McDermott
The goal of this project is to attain a systems level understanding of the soil microbiome and its phenotypic response to changing moisture through a tractable, spatially explicit examination of the molecular and ecological interactions occurring...
Lead Institution: University of North Carolina at Chapel Hill
Principal Investigator: Elizabeth Shank
Soil microbial processes exert a major influence on many of our planet's ecosystems, yet our ability to directly observe the enzymatic and metabolic activities of microbes within soil is currently critically limited. This in part due to the...
Lead Institution: Pacific Northwest National Laboratory
Principal Investigator: Xiao-Ying Yu
We will use in situ chemical imaging enabled by the microfluidic reactor SALVI to study a NAVY bilgewater emulsion model. Our main objective is to understand the evolving oil-water liquid-liquid interface. Such fundamental understanding is...
Lead Institution: Pacific Northwest National Laboratory
Principal Investigator: Charles Ansong
Type 1 diabetes mellitus (T1D) is a chronic disease resulting from the autoimmune destruction of insulin-producing pancreatic beta cells. In addition to evolving ideas about the role of beta cells in genetic susceptibility to T1D, there is mounting...
Lead Institution: Pacific Northwest National Laboratory
Principal Investigator: Sebastien Kerisit
The presence of mineral surfaces and of microorganisms significantly impacts the nature and composition of mineral phases formed in biogeochemical systems. Despite the importance of these heterogeneous reactions, predictions of the fate of...

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