Environmental Molecular Sciences Laboratory

A DOE Office of Science User Facility

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User Projects

The following is a list of projects that have been active over the past three years.
For a comprehensive list of projects, see All Projects. You can also search for released data.
Lead Institution: Lawrence Berkeley National Laboratory
Principal Investigator: Kolby Jardine
Polysaccharides are major components of plant cell walls that can be converted into fuels by microbial fermentation, making plant biomass an important bioenergy resource. However, a substantial fraction of plant cell wall polysaccharides are...
Lead Institution: University of British Columbia
Principal Investigator: Steven Hallam
Plant and microbial biomass offers a renewable alternative to energy and materials produced from oil. The industrial scale production or biorefining of sugars and aromatic compounds from biomass needs more effective and efficient biocatalysts. For...
Lead Institution: Donald Danforth Plant Science Center
Principal Investigator: Dilip Shah
Antimicrobial peptides (AMPs) are a major component of innate immunity against infectious diseases in animals and plants [2]. A feature prominent in many families of AMPs, such as defensins (Figure 1), is disulfide covalent crosslinks between pairs...
Lead Institution: Pacific Northwest National Laboratory
Principal Investigator: Alex Beliaev
Directed evolution and targeted trait selection remain among the most powerful and successful tools available for attaining the process improvements necessary to enable commercial success in many biotechnology sectors. Our team is using "solar-...
Lead Institution: Lawrence Berkeley National Laboratory
Principal Investigator: Kolby Jardine
Polysaccharides are major components of plant cell walls that can be converted into fuels by microbial fermentation, making plant biomass an important bioenergy resource. However, a substantial fraction of plant cell wall polysaccharides are...
Lead Institution: Washington State University
Principal Investigator: Norman Lewis
Our overall aim is to further identify, dissect, and exploit dirigent protein (DP) mediated supramolecular protein complexes for macromolecular lignin assembly in order to ultimately achieve facile biomass deconstruction. Our ongoing EMSL work has...
Lead Institution: University of California, Santa Barbara
Principal Investigator: Michelle O'Malley
We recently uncovered the biosynthetic machinery to produce a wide array of secondary metabolites within the genomes of the anaerobic fungal phylum Neocallimastigomycota. These fungi live among complex microbial consortia that degrade biomass within...
Lead Institution: University of Massachusetts Amherst
Principal Investigator: Kristen DeAngelis
Climate change is a current crisis that requires reduced reliance on non-renewable fuels, and lignocellulose offers an abundant and undervalued renewable fuel alternative. Lignin is a strong barrier to the conversion of cellulose to biofuels, and...
Lead Institution: Pacific Northwest National Laboratory
Principal Investigator: Jason McDermott
The goal of this project is to attain a systems level understanding of the soil microbiome and its phenotypic response to changing moisture through a tractable, spatially explicit examination of the molecular and ecological interactions occurring...
Lead Institution: National Renewable Energy Laboratory
Principal Investigator: Davinia Salvachua Rodriguez
White rot fungi (WRF) are the most efficient organisms for the depolymerization and mineralization of lignin to CO2 and H2O in Nature and thus, WRF play a pivotal role in carbon cycling. Lignin depolymerization by WRF (extracellular process) has...