Environmental Molecular Sciences Laboratory

A DOE Office of Science User Facility

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Biosystem Dynamics & Design

Biosystem Dynamics and Design focuses on regulation of spatial and temporal parameters of metabolic processes in microbes, fungi, and plants. By gaining a detailed understanding of how biological systems respond to and modify their environment, EMSL can improve strategies for modifying and manipulating plants, fungi and microbes to advance systems biology for bioenergy and biorenewables.

Within this science theme, EMSL will employ our research and that of our users for:

  • Metabolic compartmentalization: Integrate molecular-scale information to determine the design principles underlying biological compartments, structures and networks such as lipid particles and peroxisomes in plants and fungi, and the carboxysome in cyanobacteria.

Leads

No leads are available at this time.

Instruments

The SMSAS is a multi-technique surface analysis instrument based on elemental mapping using either scanning small spot X-rays or the electronics in...
Custodian(s): Shuttha Shutthanandan
The W-band pulsed EPR spectrometer, introduced in 2011, is one of only two of its design worldwide. It uses a Quasi-optical bridge and an induction-...
Custodian(s): Eric Walter
The Exactive MS provides ultra-high resolution MS capability and will be coupled with elemental/isotopic ion sources to provide truly unique and...
Custodian(s): David Koppenaal, Mary Lipton
More details about this instrument will be available soon.
Custodian(s): David Koppenaal, Mary Lipton
The Neptune is a mid-resolution, multi-collector ICP-MS instrument capable of simultaneous collection of up to nine elemental/isotopic masses,...

Publications

Trichoderma reesei is a ‘workhorse’ fungus that produces glycosyl hydrolases (e.g., cellulases) at high titers for use in industrial...
Although the gut microbiome plays important roles in host physiology, health and disease1, we lack understanding of the complex interplay between...
Ischemia-reperfusion (I/R) results in altered metabolic and molecular responses, and phosphorylation is one of the most noted regulatory mechanisms...
Chlamydomonas reinhardtii is a unicellular chlorophyte alga that is widely studied as a reference organism for understanding photosynthesis, sensory...
Cyanobacteria, such as Synechocystis sp. PCC 6803, utilize large antenna systems to optimize light harvesting and energy transfer to reaction centers...

Science Highlights

Posted: August 14, 2018
The Science In areas that flood frequently, microbial communities must adapt to repeated wet-dry cycles. Metabolic strategies help them survive, but...
Posted: August 14, 2018
The Science By fixing atmospheric nitrogen, some bacteria are able to help plants like beans, peas, and clovers thrive. How? A recent study shows...
Posted: May 23, 2018
The Science The devastating effects of drought are expected to increase in severity and frequency in the coming years. To protect the world’s food...
Posted: April 20, 2018
The Science Advanced microscopes using a beam of electrons rather than light give scientists powerful tools to investigate biological and mineral...
Posted: March 29, 2018
The Science For years, scientists have experimented with phages—the viruses that infect bacteria—to learn how they change their host. Because such...

Instruments

There are no related projects at this time.

Biosystem Dynamics and Design focuses on regulation of spatial and temporal parameters of metabolic processes in microbes, fungi, and plants. By gaining a detailed understanding of how biological systems respond to and modify their environment, EMSL can improve strategies for modifying and manipulating plants, fungi and microbes to advance systems biology for bioenergy and biorenewables.

Within this science theme, EMSL will employ our research and that of our users for:

  • Metabolic compartmentalization: Integrate molecular-scale information to determine the design principles underlying biological compartments, structures and networks such as lipid particles and peroxisomes in plants and fungi, and the carboxysome in cyanobacteria.

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