The 2020 EMSL User Meeting—Visualizing the Proteome, was held virtually from October 5-8.
This 3-day meeting encompassed the following topics:
Pushing the frontier of structural biology
Understanding subcellular compartmentalization and ultrastructure
Annotating protein function and modifications via native and top-down proteomics
Revealing cellular complexity and dynamics with single to few-cell proteomics
Advancing cellular models and protein design with high-performance computing
Attendees included international researchers from academia, industry, and government research laboratories. The EMSL User Meeting is open to EMSL users and non-users alike.
2020 EMSL User Meeting: Day One
The first day of the 2020 EMSL User Meeting included:
- Session 1: Pushing the frontier of structural biology with integrated approaches, chaired by EMSL Chemist James Evans.
- EMSL Chemist James Evans presents "Vision for EMSL visual proteomics."
- EMSL Chemist, Dusan Velickovic, presents "Molecular Snapshots of complex environmental biochemistry," a discussion of the research that led to his 2020 MT Thomas Award for Outstanding Postdoctoral Achievement.
- Tutorial 1: Cryogenic Electron Microscope, presented by EMSL Chemist Trevor Moser.
Gap junction channels visualized in a dynamic lipid environment
Structural basis for strand transfer inhibitor binding to HIV intasomes
Pterocarpan synthase (PTS) structures suggest a common quinone methide-stabilizing function in dirigent proteins with dirigent-like domains
Vision for EMSL Visual Proteomics
Single particle cryo-electron microscopy tutorial
2020 EMSL User Meeting: Day Two
The second day of the 2020 EMSL User Meeting included:
- Session 2: Peering inside cells to understand subcellular compartmentalization and ultrastructure, chaired by EMSL Chemist Trevor Moser.
- Session 3: Revealing cellular complexity and dynamics with single to few cell proteomics, chaired by EMSL Chemist Ying Zhu.
- Tutorial 2: Few-cell proteomics, presented by EMSL Chemist Ying Zhu.
Recent developments in whole cell cryo-electron tomography
Leveraging Super High Optical Resolution Microscopy to Probe the Interaction Zone Between Clostritium thermocellum and Biomass
Endophyte-Promoted Phosphorous Solubilization in Populus
Microfluidic sample preparation for EM Protein purification, single cell analysis, and visual proteomics
Single-cell mass spectrometry goes embryonic
2020 EMSL User Meeting: Day Three
The third day of the 2020 EMSL User Meeting included:
How unique is your plasma proteome? A personalized perspective
Towards Protein Structures from Native Mass Spectrometry & Single Particle Imaging
Automated capillary isoelectric focusing-tandem mass spectrometry for qualitative and quantitative top-down proteomics
Interactome studies in aging and heart failure
Native Mass Spectrometry tutorial
2020 EMSL User Meeting: Day Four
The fourth day of the 2020 EMSL User Meeting included: