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Bobbie-Jo Webb-Robertson

Institution
Pacific Northwest National Laboratory

Projects

BetaMarker: Biomarkers of Beta Cell Stress in Type 1 Diabetes

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Thomas Metz
Type 1 diabetes (T1D) is generally accepted to result from impaired immune tolerance, leading to the autoimmune destruction of islet beta cells. However, the durable preservation of beta cell…

BetaMarker: Biomarkers of Beta Cell Stress in Type 1 Diabetes

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Thomas Metz
Type 1 diabetes (T1D) is generally accepted to result from impaired immune tolerance, leading to the autoimmune destruction of islet beta cells. However, the durable preservation of beta cell…

Undiagnosed Diseases Network Metabolomics Core

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Thomas Metz
A state of the art metabolomics core will be a vital part of the Undiagnosed Diseases Network (UDN). However, in order for the UDN to realize it’s the full potential it is essential that the…

High-performance Support Vector Machines for Data-Intensive Applications

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Christopher Oehmen
Project type
Limited Scope
Support vector machines (SVM) are a software technology with broad applicability for creating binary classifiers using training data. In much the same way that SCALAPACK efficiently enables many…

Massively Parallel Molecular Profiling of Breast Cancer

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Smith
Molecular profiling of breast cancer into subcategories based on functional ER expression and amplification of HER2 has significantly enhanced our understanding of the disease, and has pointed the…

Diagnosis of sub-clinical cryptic group A streptococcal myonecrosis

Lead Institution
Boise VA Medical Center
Principal Investigator
Amy Bryant
Invasive group A streptococcal (GAS) infections associated with shock, multi-organ failure, necrotizing fasciitis with myonecrosis, and death emerged worldwide in the mid-1980s prompting an official…

Multi-platform 'Omics Analysis to Determine TB Vaccine Correlates

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Jennifer Kyle
In recent years, mass spectrometry-based integrated multi-omics analyses have allowed for powerful interrogations of patient samples, and the identification of correlates of risk for tuberculosis…

Do Your Gut Microbes Make You Moody?

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Sneha Couvillion
Attention-Deficit/Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental disorder affecting 5- 9% of children and substantial numbers of adults. Co-occurring irritability or mood dysregulation…

OHSU-PNNL Northwest Co-laboratory for Integrated Omics

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Jon Jacobs
An essential component of the OHSU-PNNL Northwest CoLaboratory for Integrated Omics (CoLab) is the collaborative pursuit of joint research projects that leverage the compelling biomedical model…

Massively Parallel Molecular Profiling of Breast Cancer

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Smith
Molecular profiling of breast cancer into subcategories based on functional ER expression and amplification of HER2 has significantly enhanced our understanding of the disease, and has pointed the…

Multi-platform 'Omics Analysis to Determine TB Vaccine Correlates

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Jennifer Kyle
In recent years, mass spectrometry-based integrated multi-omics analyses have allowed for powerful interrogations of patient samples, and the identification of correlates of risk for tuberculosis…

BetaMarker: Biomarkers of Beta Cell Stress in Type 1 Diabetes

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Thomas Metz
Type 1 diabetes (T1D) is generally accepted to result from impaired immune tolerance, leading to the autoimmune destruction of islet beta cells. However, the durable preservation of beta cell…

Undiagnosed Diseases Network Metabolomics Core

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Thomas Metz
A state of the art metabolomics core will be a vital part of the Undiagnosed Diseases Network (UDN). However, in order for the UDN to realize it’s the full potential it is essential that the…