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Carrie Nicora

Institution
Pacific Northwest National Laboratory

Projects

Agile Biofoundry FY24-25

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Nathalie Munoz Munoz
This proposed EMSL Staff time proposal assists the DOE-EERE-BETO supported PNNL project: FY24-25 seven-national laboratory Agile BioFoundry (https://agilebiofoundry.org/). PNNL’s effort for this…

Multi-marker Urine Test for Detection of Aggressive Prostate Cancer

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Weijun Qian
In prostate cancer disease management over-diagnosis and over-treatment have increasingly become major public concerns. Prostate cancer is primarily detected by serum PSA screening followed by a…

Urinary Proteome Monitoring for Transplant Injury

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
David Camp
We propose to achieve the objective of identifying novel urinary biomarkers for selected categories of renal transplant injury in two phases. We will first employ a discovery phase to comprehensively…

Agile BioFoundry

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
This proposed EMSL Resource Owner project, is a sub-project supporting two DOE-EERE-BETO supported PNNL projects: FY16-17 four-national laboratory “Agile BioFoundry” (ABF) seed project and a larger…

Extracellular Research Thrust for EMSL SSA

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Kirsten Hofmockel
This project will develop a conceptual framework that defines the biotic and abiotic mechanisms regulating the persistence of mineral associated organic matter (OM). The specific goals are to…

Modeling Host Responses to Understand Severe Human Virus Infections

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Thomas Metz
This comprehensive and highly integrated systems biology program seeks to delineate the complex host responses that determine the outcome of infections with potentially lethal viruses. To achieve…

Diagnosis of sub-clinical cryptic group A streptococcal myonecrosis

Lead Institution
Boise VA Medical Center
Principal Investigator
Amy Bryant
Invasive group A streptococcal (GAS) infections associated with shock, multi-organ failure, necrotizing fasciitis with myonecrosis, and death emerged worldwide in the mid-1980s prompting an official…

Multi-marker Urine Test for Detection of Aggressive Prostate Cancer

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Weijun Qian
In prostate cancer disease management over-diagnosis and over-treatment have increasingly become major public concerns. Prostate cancer is primarily detected by serum PSA screening followed by a…

Modeling Host Responses to Understand Severe Human Virus Infections

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Smith
This comprehensive and highly integrated systems biology program seeks to delineate the complex host responses that determine the outcome of infections with potentially lethal viruses. To achieve…

Agile BioFoundry

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Jon Magnuson
This proposed EMSL Resource Owner project, is a sub-project supporting DOE-EERE-BETO supported PNNL-national laboratory Agile BioFoundry (ABF) project. PNNL’s effort for this project, which includes…

Proteomics analysis of ovulation in primates

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Sneha Couvillion
To perform a parallel genomic (RNAseq, University of Oregon) and proteomic (PNNL) assessment of the ovarian follicle in the period prior to and at different time points after an ovulatory stimulus (i…

Dissection and Deciphering of the Soil Microbiome

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Janet Jansson
This proposal aims to address key gaps in our knowledge about the composition and functional roles of the tens of thousands of microbial species in soil. Although these microorganisms carry out…

Modeling Host Responses to Understand Severe Human Virus Infections

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Smith
This comprehensive and highly integrated systems biology program seeks to delineate the complex host responses that determine the outcome of infections with potentially lethal viruses. To achieve…

Agile BioFoundry

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Jon Magnuson
This proposed EMSL Resource Owner project, is a sub-project supporting two DOE-EERE-BETO supported PNNL projects: FY16-17 four-national laboratory “Agile BioFoundry” (ABF) seed project and a larger…

Agile BioFoundry

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Kristin Burnum-Johnson
This proposed EMSL Resource Owner project, is a sub-project supporting two DOE-EERE-BETO supported PNNL projects: FY16-17 four-national laboratory “Agile BioFoundry” (ABF) seed project and a larger…

Modeling Host Responses to Understand Severe Human Virus Infections

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Smith
This comprehensive and highly integrated systems biology program seeks to delineate the complex host responses that determine the outcome of infections with potentially lethal viruses. To achieve…