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Chaevien Clendinen

Institution
Environmental Molecular Sciences Laboratory

Projects

Integrated Pennycress Resilience Project (IPReP)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Pubudu Handakumbura
Pennycress (Thlaspi arvense) is under development as a winter annual oilseed bioenergy crop for the 80 million-acre U.S. Midwest Corn Belt and other temperate regions including the Pacific Northwest…

Determining the Metabolome and Lipidome of Amniotic Fluid Across Gestation

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Chaevien Clendinen
The existing literature suggests that the composition of AF is dynamic and changes across gestation. It is rich in proteins, lipids, oligosaccharides, RNAs, and metabolites that potentially influence…

Pentosan Polysulfate Sodium Profiling with Mass Spectrometry

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
John Cort
PPS is a semisynthetic heterogeneous sulfated polysaccharide derived from xylan, the β-1,4-linked polymer of xylose that is the backbone structural component of hemicellulose in most types of wood…

Deep spatial metabolomics for confidential molecular identification

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Marija Velickovic
This project will improve metabolite identification of plant systems and microbial communities by employing an LC separation for every coordinate probed. Current imaging techniques for metabolite…

Pentosan Polysulfate Sodium Profiling with Mass Spectrometry

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
John Cort
PPS is a semisynthetic heterogeneous sulfated polysaccharide derived from xylan, the β-1,4-linked polymer of xylose that is the backbone structural component of hemicellulose in most types of wood…

Optimization of LC-MS-based metabolomics pipeline

Lead Institution
Spanish National Research Council - CSIC
Principal Investigator
Albert Rivas-Ubach
The demand for LC-MS untargeted metabolomics analyses within EMSL user program has substantially increased during the past few years. As user facility and leading institution in mass spectrometry…

Centralized Metabolomics Molecular Reference Database

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Yuri Eberlim de Corilo
Reference databases, both in-silico and molecular standard-based, are vital components in all metabolomics data annotation workflows. However, these databases are often decentralized or have…

High-throughput rhizosphere biosensor development

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Joshua Elmore
The development of robust quantitative in situ bacterial biosensors that report on inter-organismal rhizosphere signaling, soil conditions, and plant health remains a pivotal goal for the research…