David Masica

Johns Hopkins University

Projects

Protein Structure and Surface Interactions of an Enamel Protein

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wendy Shaw

Project type

Capability Research

The structure and protein-surface interaction of an enamel protein, amelogenin, will be investigated both on and off of hydroxyapatite using solid state NMR. The formation of nanospheres (protein…

Structure determination of leucine-rich amelogenin protein adsorbed to hydroxyapatite using combined solid-state NMR and computational structure prediction

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wendy Shaw

Project type

Limited Scope

The formation of biogenic materials requires the interaction of organic molecules with the mineral phase. In forming dental enamel, the mineralization of hydroxyapatite (HAp) is largely attributed to…

Structure determination of leucine-rich amelogenin protein adsorbed to hydroxyapatite using computational structure prediction

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wendy Shaw

Project type

Exploratory Research

The formation of biogenic materials requires the interaction of organic molecules with the mineral phase. In forming dental enamel, the mineralization of hydroxyapatite (HAp) is largely attributed to…