Eric Hill

Algal Productivity Enhancements by Rapid Screening and Selection of Improved Biomass and Lipid Producing Phototrophs (APEX)

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Erin Bredeweg

This project uses a multi-pronged approach to improve oil content in algae capable of sustaining high areal biomass productivities in outdoor ponds. This includes mutagenesis techniques (EMS, ARTP)…

An integrated pest management approach to algal crop protection based on metagenomic characterization, antimicrobial peptides, and adaptive laboratory evolution

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Erin Bredeweg

This project uses a multi-pronged approach to improve pest management in open air algal cultivation, an important crop strategy for decarbonization. This includes identification of the most…

Ecophysiological Investigation of Cyanobacteria using Controlled Cultivation

Lead Institution

J. Craig Venter Institute

Principal Investigator

Yuri Gorby

Project type

Grand Challenge

This project targets the development and operation of a fully instrumented photobioreactor that will serve to cultivate Cyanobacteria under well defined and controlled conditions. This capability…

Growth analysis in mixed microbial populations using microscopy coupled with computational approaches

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Alex Beliaev

Project type

Large-Scale EMSL Research

Microbial phototroph-heterotroph associations (PHA) are common in nature as they provide basis for many water- and terrestrial-based ecosystems. Metabolic interactions between partners are the…

Development of an Integrated EMSL MS and NMR Metabolic Flux Analysis Capability In Support of Systems Biology: Test Application for Biofuels Production

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Nancy Isern

An important element in the production of biofuels is the metabolic engineering process required to maximize the production of renewable biofuel molecules from fermentable substrates. Biofuel…

Biosystems Analysis for Determining the Impact of Nutrient Uptake on Autotroph-Heterotroph Interactions within Cyanobacterial Consortia

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Stephen Callister

Project type

Large-Scale EMSL Research

The exchange of carbon and other nutrients between microorganisms is a key factor in the establishment of microbial interactions and trophic levels. Depending upon the nutrient, the establishment of…

Integrated Capability for Metabolomics and Fluxomics

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Nancy Washton

The goal of this project is to develop an integrated cyberinfrastructure that can be used to demonstrate a novel, end-to-end metabolomics and fluxomics use case: Isotopically Non-STationary…

Unraveling New Pathways for Carbon Capture to Enhance Lipid-Biomass Feedstocks

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

Organisms have evolved a number of spatially localized processes to efficiently break down, absorb, and use necessary metabolites. Although progress has been made in identifying the genes that are…

Dynamic TEM

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

Achieving a holistic, molecular-level understanding of the structure, function and mechanism of cellular machinery remains a formidable scientific challenge. While over 100,000 protein structures…

Avicel Effluent Organic Acid Concentrations

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Eric Hill

We would like to identify the identity and concentration of all organic carbon in this one sample, since we are using this as a feed stock for further experiments.

EMSL Science Overview

Eric Hill

Projects

Algal Productivity Enhancements by Rapid Screening and Selection of Improved Biomass and Lipid Producing Phototrophs (APEX)

An integrated pest management approach to algal crop protection based on metagenomic characterization, antimicrobial peptides, and adaptive laboratory evolution

Ecophysiological Investigation of Cyanobacteria using Controlled Cultivation

Growth analysis in mixed microbial populations using microscopy coupled with computational approaches

Development of an Integrated EMSL MS and NMR Metabolic Flux Analysis Capability In Support of Systems Biology: Test Application for Biofuels Production

Biosystems Analysis for Determining the Impact of Nutrient Uptake on Autotroph-Heterotroph Interactions within Cyanobacterial Consortia

Integrated Capability for Metabolomics and Fluxomics

Unraveling New Pathways for Carbon Capture to Enhance Lipid-Biomass Feedstocks

Dynamic TEM

Avicel Effluent Organic Acid Concentrations