Fionnuala Morrish

Fred Hutchinson Cancer Research Center

Projects

Cell metabolism and c-Myc-induced growth, proliferation and neoplasia.

Lead Institution

Fred Hutchinson Cancer Research Center

Principal Investigator

Fionnuala Morrish

Project type

Capability Research

Chemical and radiological damage to cells can result in inactivation of tumor suppressors or activation of oncogenes, increasing the risk of cancer. The c-Myc oncogene (Myc) is deregulated in over 50…

Analysis of metabolic responses to signals from the oncogene c-Myc a regulator of cell growth and proliferation.

Lead Institution

Fred Hutchinson Cancer Research Center

Principal Investigator

Fionnuala Morrish

Project type

Large-Scale EMSL Research

The ability of cells to grow, generate energy and respond to environmental stimuli is directly linked to cellular signaling mechanisms. Understand how these signal are regulated is an important…

Use of biofluids and a unique inducible/reversible mouse model of aggressive neoplasia to test for cancer biomarkers.

Lead Institution

Fred Hutchinson Cancer Research Center

Principal Investigator

Fionnuala Morrish

Project type

Large-Scale EMSL Research

The early diagnosis of cancers is central to successful treatment as current therapies work most effectively with early stages of the disease. As a result there has been much recent emphasis on…