Jay Grate

Immobilized Enzymes for Bioremediation and Biosensing - Armored Enzyme Nanoparticles for Remediation of Subsurface Contaminants (JB's EMSP Project - 43946) and Nanoscale Enzyme Reactors (JB's DARPA Project - 49090)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jungbae Kim

Project type

Capability Research

Immobilized enzyme systems, stabilizing the enzyme activity, will be tested for the purposes of bioremediation and biosensing. Stabilization of enzyme activity is a critical advance that is required…

Immobilized Enzymes for Bioremediation and Biosensing

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jungbae Kim

Project type

Exploratory Research

Immobilized enzyme systems, stabilizing the enzyme activity, will be tested for the purposes of bioremediation and biosensing. Stabilization of enzyme activity is a critical advance that is required…

Materials and Methods for Multivariate Chemical Sensing

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jay Grate

Project type

Exploratory Research

This research entails an interdisciplinary effort in the development of multivariate trace detection methods suitable for or with the potential to be suitable for field analysis. Specifically, it…

Materials and Methods for Multivariate Chemical Sensing

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jay Grate

Project type

Exploratory Research

This research entails an interdisciplinary effort in the development of multivariate trace detection methods suitable for or with the potential to be suitable for field analysis. Specifically, it…

Monolayer Protected Gold Nanoparticle Investigation and Characterization

Lead Institution

Southern Oregon University

Principal Investigator

Laura Hughes

Project type

Exploratory Research

Monolayer-protected gold nanoparticles will be synthesized and characterized at Southern Oregon University and PNNL. The electron microscopy facilities at PNNL will be used to characterize…

Monolayer Protected Gold Nanoparticle Investigation and Characterization

Lead Institution

Southern Oregon University

Principal Investigator

Laura Hughes

Project type

Exploratory Research

Monolayer-protected gold nanoparticles will be synthesized and characterized at Southern Oregon University and PNNL. The electron microscopy facilities at PNNL will be used to characterize…

Micromodel Pore-Scale Displacement Studies of Brine and Supercritical CO2

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Mart Oostrom

Project type

Exploratory Research

Supercritical carbon dioxide (scCO2) sequestration in deep saline aquifers or reservoirs is, to a large extent, affected by porous medium properties, fluid properties, and interfacial interactions…

Experimental Capabilities and Fundamental Science for Geologic Carbon Sequestration: The PNNL In Situ Supercritical Suite (IS3)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kevin Rosso

Project type

Large-Scale EMSL Research

This Science Theme proposal requests EMSL access for investigators in the In Situ Supercritical Suite (IS3) component of PNNL's Carbon Sequestration Initiative (CSI). The CSI is a multi-million…

Microscopic Fluoresence Imaging of Cellulose Degradation in Microfluidic Devices

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jay Grate

Project type

Large-Scale EMSL Research

The goals of this project are to (1) test combinations of fluorescent tag, cellulose form, dye-cellulose conjugation method, and microscopy modalities to demonstrate, for the first time, the ability…

Routine 1H and 13C NMR analysis of functionalized semiconductor and metallic nanoparticles synthesized for biodetection studies

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Marvin Warner

Project type

Capability Research

The research included in this proposal involves the routine analysis of organic ligand-stabilized semiconductor nanoparticles that will serve as the signal transduction element in fluorescence-based…

Experimental Capabilities and Fundamental Science for Geologic Carbon Sequestration: The PNNL In Situ Supercritical Suite (IS3)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

John Loring

Project type

Large-Scale EMSL Research

This Science Theme proposal requests EMSL access for investigators in the In Situ Supercritical Suite (IS3) component of PNNL's Carbon Sequestration Initiative (CSI). The CSI is a multi-million…

Near Real-time Alkene Sensor for Atmospheric Aerosol Chemistry Monitoring

Lead Institution

MicroEnergy Technologies, Inc.

Principal Investigator

Reza Shekarriz

Project type

Exploratory Research

The goal for the proposed project is to be able to take advantage of the current investments made at EMSL for the development of TDS to evaluate the potential for combining the TDS with the current…

Microfluidic Oxygen Sensors

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jay Grate

The aim of this research is to create oxygen sensing fluorescent surfaces in plastic, and microfluidic structures, that are useful in the investigation of oxygen-dependent biological processes. The…

Near Real-time Alkene Sensor for Atmospheric Aerosol Chemistry Monitoring

Lead Institution

MicroEnergy Technologies, Inc.

Principal Investigator

Reza Shekarriz

Project type

Large-Scale EMSL Research

The goal for the proposed project is to be able to take advantage of the current investments made at EMSL for the development of TDS to evaluate the potential for combining the TDS with the current…

Microfluidic Oxygen Sensors

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jay Grate

The aim of this research is to create oxygen sensing fluorescent surfaces in plastic, and microfluidic structures, that are useful in the investigation of oxygen-dependent biological processes. The…

Functional Interfaces at the Nanoscale

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jay Grate

Project type

Large-Scale EMSL Research

A large number of mission areas of the US. DOE demand functional materials that will meet the operational requirements of targeted applications. Indeed, innovative solutions to pressing national…

FSFA: MOSAIC—Metabolic and Spatial Interactions in Communities

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Errol Robinson

This EMSL user proposal is to support the MOSAIC DOE BER funded FSFA at PNNL. The primary activities involving EMSL are a set of BSSD demonstration tasks focusing on key science questions and related…

Fundamental Studies of Monolayer-Protected Nanoparticles by Gas Chromatography

Lead Institution

University of Washington

Principal Investigator

Gwen Gross

Project type

Exploratory Research

As part of the JIN Award 2002, wil be working with Jay Grate and Dave Nelson to study MPN materials in more detail to understand on a fundamental level their sorptive properties, and to explore a…

FSFA: MOSAIC -- Metabolic and Spatial Interactions in Communities FY18 proposal

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Errol Robinson

This EMSL user proposal is to support the MOSAIC DOE BER funded FSFA at PNNL. The primary activities involving EMSL are a set of BSSD demonstration tasks focusing on key science questions and related…

Single Enzyme Nanoparticles

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jungbae Kim

Project type

Large-Scale EMSL Research

Enzymes are useful biocatalysts of nanometer scale that regulate the chemistry of cells and organisms. The specificity of enzymes promises great improvements in various applications such as chemical…

Functional Materials for Separation and Sensing

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jay Grate

Project type

Large-Scale EMSL Research

A large number of mission areas of the US. DOE demand functional materials that will meet the operational requirements of targeted applications. Indeed, innovative solutions to pressing national…

Projects