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Joel Pounds

Institution
Pacific Northwest National Laboratory

Projects

Implementation of Systems Toxicology for an Animal Emphysema Model

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Joel Pounds
Project type
Exploratory Research
The objective of this study is to establish a procedure on how to best incorporate the comprehensive systems toxicology database in a prototype lung disease model, the elastase-induced emphysema…

Biomarker development for chronic obstructive pulmonary disease

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
David Springer
Chronic obstructive pulmonary disease(COPD) is a common chronic disease effecting a significant portion of humans, particularly those that smoke. The goal of this work is to develop a reliable…

Nanoscale Characterization of Nanomaterial - Cell Interactions

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Galya Orr
Project type
Large-Scale EMSL Research
This proposal is a continuation of research pursued under EMSL User Proposal #17690. The extensive use of amorphous silica nanoparticles (NPs) in the industry, and the growing use of carbon nanotubes…

Discovery of Biomarkers Related to COPD

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Joel Pounds
Chronic Obstructive Pulmonary Disease (COPD) is a slowly progressive disease of the airways that is characterized by a gradual loss of lung function. COPD is a major cause of death and illness…

Proteomics Analysis for the Center for Novel Biomarkers of Response

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Jon Jacobs
The organizing theme for the PNNL U54 Center for Novel Biomarkers of Response, is that identification and validation of persistent modified proteins in plasma will provide specific information about…