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Jonathan Dworkin

Institution
Columbia University
ORCID
ORCID logo 0000-0002-8205-6918

Projects

Phosphoproteomic analysis of Bacillus subtilis

Lead Institution
Columbia University
Principal Investigator
Jonathan Dworkin
Project type
Limited Scope
Ser/Thr phosphorylation is a key mechanism of regulation in eukaryotic cells, but its role in prokaryotes is far less clear. In the past ~5 years, phosphoproteomic approaches have found that a large…

Phosphoproteomic analysis of Escherichia coli

Lead Institution
Columbia University
Principal Investigator
Jonathan Dworkin
Project type
Limited Scope
Ser/Thr phosphorylation is a key mechanism of cellular regulation in eukaryotes, but its role in prokaryotes is far less clear. In the past ~5 years, phosphoproteomic approaches have found that a…

Proteomic Insights into Mechanisms of Microbial Dormancy

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Jared Shaw
Ecologically important processes such as carbon and nutrient cycling largely depend on the active fraction of microbial communities, and only a small portion of the total soil microbiome is active…

Phosphoproteomic analysis of Escherichia coli

Lead Institution
Columbia University
Principal Investigator
Jonathan Dworkin
Project type
Limited Scope
This work will identify the substrates of a single Ser/Thr kinase and a single Ser/Thr phosphatase in the bacterium Escherichia coli using the automated IMAC technology developed by Dr. Pasa-Tolic at…