Joseph GIovinazzo

University of Colorado Anschutz Medical Campus

0000-0003-2608-7143

Projects

Determine the structural basis of splicing modulation by small molecules

Lead Institution

University of Colorado Anschutz Medical Campus

Principal Investigator

Rui Zhao

Aberrant pre-mRNA splicing contributes to 10-15 % of genetic disorders, including Spinal Muscular Atrophy (SMA). SMA is a potentially lethal neurodegenerative disorder caused by loss of function…

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…