Karl Weitz

Incorporation of Real-Time Mass Spectrometry (RTMS) and Applications into EMSL’s Integrated Research Platforms

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Karl Weitz

We propose to install an RTMS capability on EMSL’s existing high mass resolution Agilent 7250 QTOF system for the (TAP) IRP for development of first-of-kind real-time atmospheric organic monitoring…

CPTAC Proteome Characterization Center

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Tao Liu

The overall objective of the PNNL Proteome Characterization Center (PCC) is to comprehensively characterize human tumor samples provided by the National Cancer Institute (NCI), and to integrate the…

High-Throughput Proteomics: Applications and Development (PNNL Scope #40601 and #43488)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Gordon Anderson

This project involves the application and development of high-throughput proteomics and quantitative measurement capabilities within biological systems. More so, application measurements will be…

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joshua Adkins

The BER Genome Science Program aims to understand complex biological and environmental systems across spatial and temporal scales to develop predictive knowledge relevant to DOE mission challenges…

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joshua Adkins

The BER Genome Science Program aims to understand complex biological and environmental systems across spatial and temporal scales to develop predictive knowledge relevant to DOE mission challenges…

Undiagnosed Diseases Network Metabolomics Core

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Thomas Metz

A state of the art metabolomics core will be a vital part of the Undiagnosed Diseases Network (UDN). However, in order for the UDN to realize it’s the full potential it is essential that the…

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joshua Adkins

The BER Genome Science Program aims to understand complex biological and environmental systems across spatial and temporal scales to develop predictive knowledge relevant to DOE mission challenges…

Using Mass Spectrometry and 2D-NMR to characterize biomass-derived liquid and solid streams

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Mariefel Olarte

This proposal aims to generate a deeper understanding of bio-oils and lignin samples through characterization using advanced chromatography (LC and GC), mass spectrometry (MS) and nuclear magnetic…

Using Mass Spectrometry and 2D-NMR to characterize biomass-derived liquid and solid streams

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Mariefel Olarte

This proposal aims to generate a deeper understanding of bio-oils and lignin samples through characterization using advanced chromatography (LC and GC), mass spectrometry (MS) and nuclear magnetic…

Metabolomics of programmed cell death

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jennifer Kyle

Lipidomics is the study of cellular lipids to understand the function and structure of biological systems. The interaction of lipids with other cellular components, including proteins and…

Mapping Nutrient Flow through a Plant-Microbe Symbiont System using Stable Isotope Probing under Drought and Salinity Stress

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kim Hixson

Red alder (Alnus rubra) is one of the fastest growing, commercially important, hardwood species for biomass/timber production in North America, and is also involved in a nitrogen-fixation symbiosis…

CPTAC Proteome Characterization Center

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Tao Liu

The overall objective of the PNNL Proteome Characterization Center (PCC) is to integrate genomic information with proteomic technologies to comprehensively characterize the proteome and post…

Real-Time Mass Spectrometry (RT-MS) Instrument Upgrade and Development

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Karl Weitz

EMSL currently houses the only Battelle patented real-time atmospheric sampling manifold technology that is used for monitoring in situ living systems in real-time. However, using this technology…

Bonding strength of plant and microbial precursors to mineral-associated soil organic matter

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Sarah Leichty

Soil organic matter (SOM) provides ecosystem services such as soil fertility and climate mitigation, holding the key to agricultural sustainability in a rapidly changing world. Despite the important…

Non-Invasive Monitoring for Occupational Exposure to Metals

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Charles Timchalk

Project type

Exploratory Research

The assessment of the potential for health effects, and the need for protective measures requires the accurate measurement of exposure, and the ability to translate these measurements into dose. …

EMSL Science Overview

Karl Weitz

Projects

Incorporation of Real-Time Mass Spectrometry (RTMS) and Applications into EMSL’s Integrated Research Platforms

CPTAC Proteome Characterization Center

High-Throughput Proteomics: Applications and Development (PNNL Scope #40601 and #43488)

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Undiagnosed Diseases Network Metabolomics Core

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Using Mass Spectrometry and 2D-NMR to characterize biomass-derived liquid and solid streams

Using Mass Spectrometry and 2D-NMR to characterize biomass-derived liquid and solid streams

Metabolomics of programmed cell death

Mapping Nutrient Flow through a Plant-Microbe Symbiont System using Stable Isotope Probing under Drought and Salinity Stress

CPTAC Proteome Characterization Center

Real-Time Mass Spectrometry (RT-MS) Instrument Upgrade and Development

Bonding strength of plant and microbial precursors to mineral-associated soil organic matter

Non-Invasive Monitoring for Occupational Exposure to Metals