Kristoffer Brandvold

Metabolic Flux Coupling in Microbial Consortia: Demystifying Metabolic Exchanges across Species

Lead Institution

University of Tromso - The Arctic University of Norway

Principal Investigator

Hans Bernstein

Project type

Large-Scale EMSL Research

We propose to employ EMSL's state-of-the-art metabolomics capabilities to gain a predictive understanding of how compartmentalized metabolic reactions are coordinated across carbon and energy…

Rapid quantification of fecal microbiome-associated enzyme functional activities for microtiter plate-based probe assays

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Aaron Wright

Characterizing the role of gut microbiota in human drug metabolism will be an important step towards tailored/personalized therapy that would be more efficient, cost-effective, and with lower adverse…

High throughput generation of small molecule probes for discovery of unique cellular functions using Substrate Activity Screening

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Sankarganesh Krishnamoorthy

We propose a method to demystify the massive catalog of proteins-of-unknown-function accumulated by recent advances in genome sequencing by direct assignment of function. We will query enzyme…

EMSL Science Overview

Kristoffer Brandvold

Projects

Metabolic Flux Coupling in Microbial Consortia: Demystifying Metabolic Exchanges across Species

Rapid quantification of fecal microbiome-associated enzyme functional activities for microtiter plate-based probe assays

High throughput generation of small molecule probes for discovery of unique cellular functions using Substrate Activity Screening