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Leendert Dekker

Institution
Erasmus University Medical Center, Rotterdam

Projects

An integrated top-down / bottom-up method to identify disease related antibodies

Lead Institution
Erasmus University Medical Center, Rotterdam
Principal Investigator
Theo Luider
Project type
Exploratory Research
We describe the discovery of a new class of biomarkers derived from immunoglobulins using mass spectrometry. We previously investigated this approach in model systems with bottom-up proteomics, and…

Molecular imaging of amyloid beta peptide in the Alzheimer brain

Lead Institution
Erasmus University Medical Center, Rotterdam
Principal Investigator
Theo Luider
Project type
Limited Scope
The amyloid plaque is a principal pathological hallmark of the Alzheimer disease (AD) brain. Amyloid plaques are extracellular accumulations composed of the amyloid beta (Abeta) peptide and…