Linda Nicholson

Cornell University

Projects

Conformational Dynamics of Pin1 Regulation of APP processing and Abeta Production

Lead Institution

Cornell University

Principal Investigator

Linda Nicholson

Project type

Capability Research

The proposed studies fall within the EMSL science theme of "Biological Interactions and Interfaces". The experiments that we propose build on extensive literature that indicates that…

Conformational Dynamics of Pin1 Regulation of APP processing and Abeta Production

Lead Institution

Cornell University

Principal Investigator

Linda Nicholson

Project type

Large-Scale EMSL Research

The proposed studies fall within the EMSL science theme of "Biological Interactions and Dynamics", specifically in the effort to understand how the "readout", or experimentally…