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Paul Majors

Institution
Washington State University

Projects

Combined NMR/Optical Microscopy for Oral Biofilm Physiology Studies

Lead Institution
Washington State University
Principal Investigator
Paul Majors
Project type
Capability Research
Dental caries disease is one of the most prevalent and costly bacterial infections in humans. Caries and associated tooth decay are strongly correlated with a pH decrease induced by oral biofilms …

Regulatory dynamics of microbial communities

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
H Wiley
Project type
Large-Scale EMSL Research
This is a proposal to conduct work in EMSL in support of the Foundational Scientific Focus Area (FSFA) research program at Pacific Northwest National Laboratory. This large-scale research program…

In-Vivo 1H NMR Spectroscopy of Pesticide Induced Neurotoxicity

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Charles Timchalk
Project type
Limited Scope
The developing brain is uniquely vulnerable to xenobiotic exposures at levels that do not appear to adversely impact adult brain function. In children, learning disabilities, neurological…

MRI for Understanding Water Management in PEM Fuel Cells

Lead Institution
Brown University
Principal Investigator
Li-Qiong Wang
Project type
Capability Research
Real-time, 3-dimensional analysis methods are currently needed to probe polymer electrolyte membrane (PEM) fuel cell performance and degradation. Magnetic Resonance Imaging (MRI) has tremendous…

NMR microscopy of diffusive transport in natural porous mineral grains

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Chongxuan Liu
Project type
Capability Research
We propose further 1H NMR studies of water-saturated natural porous mineral granules in order to investigate fluid transport in these materials. Previous significant distortions due to the…

COMBINED NMR/OPTICAL MICROSCOPY OF BIOFILM PHYSIOLOGY STUDIES

Lead Institution
Washington State University
Principal Investigator
Paul Majors
Project type
Large-Scale EMSL Research
Bacterial biofilms are found nearly everywhere in nature. Microbial metabolism and phenotype vary rapidly within a biofilm - this is at least partly responsible for their metabolic diversity and…

Imaging Of Water and Gas Distribution in PEM Fuel Cell Stacks and Cells

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Kevin Minard
Project type
Large-Scale EMSL Research
The overall objective of this project is to develop three-dimensional magnetic resonance imaging (MRI) for in-situ, real-time monitoring of polymer electrolyte membrane (PEM) fuel cell…

Electron Transfer Mechanisms in Biofilms

Lead Institution
Washington State University
Principal Investigator
Haluk Beyenal
Project type
Large-Scale EMSL Research
Although interactions of microorganisms with electrodes have been studied in the literature, the mechanisms of electron transfer are still poorly understood. The goal of this proposal is to…

NMR/OPTICAL Microscopy Studies of Oral Plaque Ecology

Lead Institution
University of California, Los Angeles
Principal Investigator
Wenyuan Shi
Project type
Large-Scale EMSL Research
Current tooth decay (dental caries) prevention methods include enamel hardening with fluoride and bacterial removal via mechanical and general antimicrobial approaches. These methods are based on the…