Rohit Kulkarni

Collaborative Research Projects Supported by the NCRR P41 Resource Center

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Camp

Project type

Large-Scale EMSL Research

The Proteomics Resource Center for Integrative Biology at PNNL was established in 2003 and builds on the unique instrumentation and the infrastructure provided by PNNLs EMSL facility. The mission of…

Proteomic Studies of type 2 diabetes using knockout models

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Weijun Qian

A central goal of diabetes research (type 1 and type 2) is to generate large numbers of functional islets or beta-cells for replacement therapy. Therefore, a fundamental knowledge of mechanisms and…

Collaborative research projects in the PNNL NIH NCRR P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Camp

Collaborative research projects in the PNNL NIH NCRR P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Proteomic Studies of type 2 diabetes using knockout mouse models

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Weijun Qian

This is an NIH-funded R01 project on diabetes research. A central goal of diabetes research (type 1 and type 2) is to generate large numbers of functional islets or beta-cells for replacement…

Collaborative research projects in the PNNL NIH NCRR P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Jon Jacobs

Collaborative research projects in the PNNL NIH NCRR P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Weijun Qian

In type 1 diabetes (T1D) research there remains a critical need for having a systems level understanding of the early stage molecular mechanisms that trigger the specific destruction of pancreatic β…

Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Jon Jacobs

Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Serum biomarkers for predicting type 1 diabetes

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Weijun Qian

Clinical type 1 diabetes (T1D) is preceded by an asymptomatic phase of the disease, which can be readily identified by serum islet autoantibodies(AAb). However, the T1D field is challenged by the…

Pilot Study on Examination of LIRKO Islets and Serum Using Quantitative Proteomic Approaches

Lead Institution

Joslin Diabetes Center

Principal Investigator

Rohit Kulkarni

A central goal of diabetes research (type 1 and type 2) is to generate large numbers of functional islets or &#61538;-cells for replacement therapy. Therefore, a fundamental knowledge of…