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Ryan Kelly

Institution
Brigham Young University

Projects

Microscopic Fluoresence Imaging of Cellulose Degradation in Microfluidic Devices

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Jay Grate
Project type
Large-Scale EMSL Research
The goals of this project are to (1) test combinations of fluorescent tag, cellulose form, dye-cellulose conjugation method, and microscopy modalities to demonstrate, for the first time, the ability…

Platform for Large-Scale Determination of Protein-Ligand Binding

Lead Institution
North Carolina State University
Principal Investigator
Erin Baker
Noncovalent protein-ligand interactions play a major role in many biological processes including signal transduction, enzymatic catalysis and immune response and determining those interactions is…

Nanoparticle / PDMS-based Microfluidic Device for Environmental Monitoring

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Jun Wang
Project type
Exploratory Research
This proposal is to develop nanoparticle-based microfluidic chips for multiplexed detection of environmental biomarkers. We will choose the poly(dimethylsiloxane) (PDMS) to fabricate the microfluidic…

Free Space Transistors for Advancing the Art of Software Defined Radio

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Ethan Farquhar
CMOS transistors have driven the technological change of the past generation. However, they have speed limits that cannot be exceeded, and these limits have restrained some areas especially in the…

Rhizosphere processes at molecular to core scale

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Nancy Hess
The amount of C in soil far exceeds the C content of atmosphere as well as the amount C stored above ground as plant biomass. The C fluxes between atmosphere and biomass are huge, many orders of…

Characterization of single cell dynamics using microfluidics

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Bryan Linggi
Cell communities exhibit complex responses to changes in their environment. Studying the molecular changes (e.g., RNA and protein) associated with these changes is likely to improve the ability to…

Validation and Advanced Development of Emerging Technologies

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Keqi Tang
Develop mass spectrometry (MS) based assays for quantitative biomarker validation with sensitivity and specifically comparable to or better than antibody based immunoassays. The new liquid…

Synthesis with Atomic Scale Control for Highly Selective Catalysts

Lead Institution
Virginia Polytechnic Institute
Principal Investigator
Ayman Karim
The proposed work is focused on catalyst design for the conversion of biomass to fuels and chemicals. Specifically, we propose a rational design methodology aimed at controlling the catalyst…

Platform for Large-Scale Determination of Protein-Ligand Binding

Lead Institution
North Carolina State University
Principal Investigator
Erin Baker
Noncovalent protein-ligand interactions play a major role in many biological processes including signal transduction, enzymatic catalysis and immune response and determining those interactions is…

Free Space Transistors for Advancing the Art of Software Defined Radio

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Ethan Farquhar
CMOS transistors have driven the technological change of the past generation. However, they have speed limits that cannot be exceeded, and these limits have restrained some areas especially in the…

FSFA: MOSAIC—Metabolic and Spatial Interactions in Communities

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Errol Robinson
This EMSL user proposal is to support the MOSAIC DOE BER funded FSFA at PNNL. The primary activities involving EMSL are a set of BSSD demonstration tasks focusing on key science questions and related…

Integrated multi-omic analysis of high lipid accumulation in the oleaginous green microalgae Ostreococcus tauri to engineer metabolic pathways for improved triacylglycerol feedstocks

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
Project type
Exploratory Research
Our proposed mutli-omic approach will empower a comprehensive understanding of cellular pathways linking carbon, nitrogen and phosphate metabolism in the microalga Ostreococcus tauri. The use of this…