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Tao Liu

Institution
Pacific Northwest National Laboratory
ORCID
ORCID logo 0000-0001-9529-6550

Projects

CPTAC Proteome Characterization Center

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
The overall objective of the PNNL Proteome Characterization Center (PCC) is to comprehensively characterize human tumor samples provided by the National Cancer Institute (NCI), and to integrate the…

Molecular analysis of exRNA carrier subclasses

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
As a consortium site, PNNL will perform proteomic and lipidomic analysis of exosome RNA (exRNA) carrier subclass samples generated using differential centrifugation, density gradient centrifugation,…

Integrated multi-omics analysis of multiple myeloma

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
In this project, integrated quantitative global proteomics and phosphoproteomics analysis of multiple myeloma cases (unsorted and sorted cell types) will be performed using multiplexed tandem mass…

OHSU-PNNL NORTHWEST CO-LABORATORY FOR INTEGRATED OMICS

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Karin Rodland
An essential component of the OHSU-PNNL Northwest CoLaboratory for Integrated Omics (CoLab) is the collaborative pursuit of joint research projects that leverage the compelling biomedical model…

Longitudinal Proteomic Characterization of Human Cerebrospinal Fluid

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
In order to facilitate future studies of diseased or drug-altered biological conditions by monitoring human cerebrospinal fluid (CSF) it is necessary to begin by creating a database/roadmap or…

CPTAC Proteome Characterization Center

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
The overall objective of the PNNL Proteome Characterization Center (PCC) is to integrate genomic information with proteomic technologies to comprehensively characterize the proteome and post…

Longitudinal Proteomic Characterization of Human Cerebrospinal Fluid

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
In order to facilitate future studies of diseased or drug-altered biological conditions by monitoring human cerebrospinal fluid (CSF) it is necessary to begin by creating a database/roadmap or…

OHSU-PNNL NORTHWEST CO-LABORATORY FOR INTEGRATED OMICS

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Karin Rodland
An essential component of the OHSU-PNNL Northwest CoLaboratory for Integrated Omics (CoLab) is the collaborative pursuit of joint research projects that leverage the compelling biomedical model…

PTRC Proteogenomic Translational Research Center

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Paul Piehowski
Due to the complexity of signaling and sequence modifications in cancer, predictions of pathway regulation and dependence based upon genomic data alone is challenging. This research proposal will…

Longitudinal Proteomic Characterization of Human Cerebrospinal Fluid

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
In order to facilitate future studies of diseased or drug-altered biological conditions by monitoring human cerebrospinal fluid (CSF) it is necessary to begin by creating a database/roadmap or…

Cancer Moonshot - Framingham

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
The purpose of the Cancer Moonshot -Framingham projects is to perform multiplexed, quantitative LC-MS analysis of longitudinal serum samples associated with head and neck cancer, B-cell lymphoma,…

PTRC Proteogenomic Translational Research Center

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Karin Rodland
Due to the complexity of signaling and sequence modifications in cancer, predictions of pathway regulation and dependence based upon genomic data alone is challenging. This research proposal will…

OHSU-PNNL Northwest Co-laboratory for Integrated Omics

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Jon Jacobs
An essential component of the OHSU-PNNL Northwest CoLaboratory for Integrated Omics (CoLab) is the collaborative pursuit of joint research projects that leverage the compelling biomedical model…

Proteomic Analysis of the HMEC Mitogenic Response

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Brian Thrall
Project type
Exploratory Research
This EMSL User Proposal is for a collaborative effort with the PNNL Proteomic National Center for Research Resources. Recent studies from our and others’ laboratories have demonstrated that the…

Massively Parallel Molecular Profiling of Breast Cancer

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Smith
Molecular profiling of breast cancer into subcategories based on functional ER expression and amplification of HER2 has significantly enhanced our understanding of the disease, and has pointed the…

Metabolic regulation of O-GlcNAc and cardiac function during hypertrophy

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Ljiljana Pasa-Tolic
Despite treatment advances, half of patients suffering from heart failure die within five years of diagnosis, while those who survive may live with severe disabilities. Cardiac hypertrophy poses a…

Proteomic Studies of Inflammation and the Host Response to Injury

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Weijun Qian
Inflammation and The Host Response to Injury, a large scale collaborative research program, is currently funded as a "glue" grant by the National Institute of General Medical Sciences …

Cancer Moonshot - Framingham

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
The purpose of the Cancer Moonshot -Framingham project is to apply multiplex quantitative LC-SRM-MS assays for comprehensive, quantitative analysis of longitudinal serum samples associated with head…

The Role of Myeloid Cells in Parkinson’s Disease

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
Parkinson’s disease (PD) is a progressive, neurodegenerative disorder of aging that affects both motor and cognitive function. Despite more than fifty years of research, no cures exist and the…

PTRC Proteogenomic Translational Research Center

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Paul Piehowski
Due to the complexity of signaling and sequence modifications in cancer, predictions of pathway regulation and dependence based upon genomic data alone is challenging. This research proposal will…

OHSU-PNNL NORTHWEST CO-LABORATORY FOR INTEGRATED OMICS

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Jon Jacobs
An essential component of the OHSU-PNNL Northwest CoLaboratory for Integrated Omics (CoLab) is the collaborative pursuit of joint research projects that leverage the compelling biomedical model…

Collaborative Research Projects Supported by the NCRR P41 Resource Center

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
David Camp
Project type
Large-Scale EMSL Research
The Proteomics Resource Center for Integrative Biology at PNNL was established in 2003 and builds on the unique instrumentation and the infrastructure provided by PNNLs EMSL facility. The mission of…

Massively Parallel Molecular Profiling of Breast Cancer

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Smith
Molecular profiling of breast cancer into subcategories based on functional ER expression and amplification of HER2 has significantly enhanced our understanding of the disease, and has pointed the…

Prophylactic Cancer Vaccine

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
Are there a collection of neo-antigens produced by tumor cells at critical stages of a tumor growth such that if one were vaccinated against them most if not all tumors would be eliminated before…

Cancer Moonshot - Framingham

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
The purpose of the Cancer Moonshot -Framingham project is to continue finishing analysis of ~1300 serum samples with applying multiplex quantitative LC-SRM-MS assays for comprehensive, quantitative…

Longitudinal Proteomic Characterization of Human Cerebrospinal Fluid

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
In order to facilitate future studies of diseased or drug-altered biological conditions by monitoring human cerebrospinal fluid (CSF) it is necessary to begin by creating a database/roadmap or…

Longitudinal Proteomic Characterization of Human Cerebrospinal Fluid

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
In order to facilitate future studies of diseased or drug-altered biological conditions by monitoring human cerebrospinal fluid (CSF) it is necessary to begin by creating a database/roadmap or…

Metabolic regulation of O-GlcNAc and cardiac function during hypertrophy

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Ljiljana Pasa-Tolic
Despite treatment advances, half of patients suffering from heart failure die within five years of diagnosis, while those who survive may live with severe disabilities. Cardiac hypertrophy poses a…

OHSU-PNNL NORTHWEST CO-LABORATORY FOR INTEGRATED OMICS

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Karin Rodland
An essential component of the OHSU-PNNL Northwest CoLaboratory for Integrated Omics (CoLab) is the collaborative pursuit of joint research projects that leverage the compelling biomedical model…

WRI Breast Cancer

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
The aim of this pilot project is to obtain comprehensive data on protein expression from breast tumor samples in the WRI tissue repository from patients that are stratified by having negative or…

CPTAC Proteome Characterization Center

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Tao Liu
The overall objective of the PNNL Proteome Characterization Center (PCC) is to integrate genomic information with proteomic technologies to comprehensively characterize the proteome and post…