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Thomas Spiro

Institution
University of Washington

Projects

Manganese biomineralization by the bacterial protein complex Mnx

Lead Institution
University of Washington
Principal Investigator
Bradley Tebo
Project type
Large-Scale EMSL Research
Manganese-oxide mineral formation by bacterial oxidation of dissolved Mn(II) is an important process in aquatic and soil environments and is a key part of the global Mn cycle. The Mn bio-oxides…

Structure of the first purified manganese oxidase Mnx

Lead Institution
University of Washington
Principal Investigator
Bradley Tebo
Microbial production of manganese oxide (MnO2) is a globally important biomineralization process. MnO2 is a key component of the Mn cycle, which supports life through the Mn catalytic centers of many…

Structure of the first purified manganese oxidase Mnx

Lead Institution
University of Washington
Principal Investigator
Bradley Tebo
This project aims to obtain high-resolution atomic structure of the first purified bacterial manganese-oxidizing complex, Mnx. This complex, containing the novel multicopper oxidase MnxG enzyme, has…