William Nelson | Environmental Molecular Sciences Laboratory

Prediction of response of microbial interaction networks cycling carbon to changing moisture conditions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Ryan McClure

Harnessing the soil microbiome presents transformational opportunities to optimize the economic and environmental value of our nation’s soil microbiomes, including maintaining soil organic matter…

Moisture and seasonal drivers of Inter-Kingdom metabolic interaction in a marginal soil rhizosphere

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

William Nelson

Project type

FICUS Research

Soil is a complex environment with numerous competing and cooperating populations contributing to overall ecosystem services. Plants provide most of the fresh organic carbon inputs through growth and…

Advancing ecosystem understanding of carbon turnover and storage through molecular characterization

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kirsten Hofmockel

EMSL Staff Proposal: The coupling between concurrently changing carbon (C) and nitrogen (N) cycles remains a key uncertainty in understanding feedbacks between the terrestrial C cycle and climate…

Development of Novel Approaches to Target Microbial Drivers of C Cycling in Soil Aggregates

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kirsten Hofmockel

This proposal seeks to provide much needed insight into the microbial controls of terrestrial C cycling through the development of a novel research approach that integrates multiple technologies, and…

Prediction of soil microbiome phenotypic responses to changing moisture conditions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jason McDermott

The goal of this project is to attain a systems level understanding of the soil microbiome and its phenotypic response to changing moisture through a tractable, spatially explicit examination of the…

Prediction of soil microbiome phenotypic responses to changing moisture conditions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jason McDermott

The goal of this project is to attain a systems level understanding of the soil microbiome and its phenotypic response to changing moisture through a tractable, spatially explicit examination of the…

Influences of Hydrologic Exchange Flows on River Corridor and Watershed Biogeochemical Function

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Stegen

We are developing predictive understanding of the processes that govern influences of hydrologic exchange flows on water quality, nutrient dynamics, and ecosystem health in dynamic river corridor…

Elucidating the molecular mechanism of gut microbiome response to the Specific Carbohydrate Diet in pediatric patients with inflammatory bowel disease

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

William Nelson

Pediatric Inflammatory Bowel Disease (IBD) is a debilitating condition that includes ulcerative colitis (UC) and Crohn's disease (CD). It affects 1.4 million children and adults in the US, at an…

Pore to core: Changes in osmotic conditions due to varying antecedent soil moisture conditions drive microbial community composition

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Vanessa Bailey

Recent research has shown that bacterial invasion by phage, detected via CRISPR inserts, increases with increasing osmotic stress. We seek access to EMSL computing resources to explore existing…

Prediction of response in soil microbiome carbon utilization to changing moisture conditions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jason McDermott

Project type

FICUS Research

The goal of this project is to attain a systems level understanding of the soil microbiome and its phenotypic response to changing moisture through a tractable, spatially explicit examination of the…

Influences of Hydrologic Exchange Flows on River Corridor and Watershed Biogeochemical Function

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Stegen

We are developing predictive understanding of the processes that govern influences of hydrologic exchange flows on water quality, nutrient dynamics, and ecosystem health in dynamic river corridor…

Prediction of soil microbiome phenotypic responses to changing moisture conditions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jason McDermott

The goal of this project is to attain a systems level understanding of the soil microbiome and its phenotypic response to changing moisture through a tractable, spatially explicit examination of the…

Multi-watershed perturbation-response traits derived through ecological theory

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Stegen

Project type

Large-Scale EMSL Research

This project will transform our ability to understand and predict how the influences of biogeochemical hot spots and hot moments on surface-subsurface systems are altered by disturbance. New theory…

ABPP of Opioid and Sedative Receptors to Improve Medical Countermeasure Development

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Aaron Wright

This EMSL Resource Owner proposal seeks to utilize Orbitrap MS capabilities for advancing our understanding of opioid and sedative exposures, which could lead to developing safe and efficacious…

Coupling Microbial Communities to Carbon and Contaminant Biogeochemistry in the Groundwater-Surface Water Interaction Zone

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Stegen

Project type

FICUS Research

The proposed study will integrate molecular data generated through a combination of JGI and EMSL capabilities to support research activities under the Subsurface Biogeochemical Research-Science Focus…

Prediction of response of microbial interaction networks cycling carbon to changing moisture conditions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Ryan McClure

Harnessing the soil microbiome presents transformational opportunities to optimize the economic and environmental value of our nation’s soil microbiomes, including maintaining soil organic matter…

Pore- to Core-Scale Research to Inform Ecosystem-Scale Soil C Biogeochemistry

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Vanessa Bailey

Project type

Large-Scale EMSL Research

The spatial separation of soil organic carbon (SOC), microbes, and extracellular activity is an important mechanism of SOC protection in soils that exists at the soil pore (micron-mm) scale. The…

Spatially-resolved, consortial approaches towards a mechanistic understanding of soil nitrogen fate

Lead Institution

Purdue University

Principal Investigator

Stephen Lindemann

Nitrogen acquisition is a key determinant of plant productivity and the fate of nitrogen, both applied and endogenous, is largely controlled by microbial processes. Furthermore, microbially-induced…

Influences of Hydrologic Exchange Flows on River Corridor and Watershed Biogeochemical Function

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Stegen

We are developing predictive understanding of the processes that govern influences of hydrologic exchange flows on water quality, nutrient dynamics, and ecosystem health in dynamic river corridor…

Projects