Xueyun Zheng

Robust data analysis tool for locating lipid C=C double bonds and isomer separation

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Xueyun Zheng

A complete lipidomics workflow that enables isomer separation and complete structural elucidation is being developed. The goal of this project is to develop robust bioinformatics tools that allow…

Platform for Large-Scale Determination of Protein-Ligand Binding

Lead Institution

North Carolina State University

Principal Investigator

Erin Baker

Noncovalent protein-ligand interactions play a major role in many biological processes including signal transduction, enzymatic catalysis and immune response and determining those interactions is…

Statistical Methodology for Characterization of Macromolecular Similarity

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

John Cort

As with any drug, approval of generic versions of macromolecular drugs requires rigorous evaluation of therapeutic equivalence to the reference drug in order to assure similar efficacy and safety…

High Resolution High Throughput Proteomics Platform for Cancer Research

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Yehia Ibrahim

The objective of this project is to develop and evaluate a new high-throughput and ultra-sensitive platform that will enable more effective and higher throughput proteomics measurements to support…

A Molecular Atlas of the Developing Lung

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joshua Adkins

The United States is one of the top nations for prematurely born infants and has a correspondingly high dayone infant mortality rate. Expanding our understanding of alveologenesis is a critical step…

Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Jon Jacobs

Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

High Resolution High Throughput Proteomics Platform for Cancer Research

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Yehia Ibrahim

The objective of this project is to develop and evaluate a new high-throughput and ultra-sensitive platform that will enable more effective and higher throughput proteomics measurements to support…

Resolution of Lipid Structural Diversity for Threat-Agnostic Signature Development

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jennifer Kyle

Development of threat-agnostic biosignatures is critical for detection of and response to biological threats that go beyond the historical list-based approach. Lipids are a class of structurally…

Characterizing the contribution of bioaerosols diversity from complex aerosol particle samples.

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Swarup China

Current global change scenarios expect to significantly increase the contribution of pollen to the total organic aerosol budget. In addition, pollen can burst into smaller fragments that are highly…

Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Jon Jacobs

Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

A Molecular Atlas of the Developing Lung

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joshua Adkins

The United States is one of the top nations for prematurely born infants and has a correspondingly high dayone infant mortality rate. Expanding our understanding of alveologenesis is a critical step…

Projects