Routine 1H and 13C NMR analysis of functionalized semiconductor and metallic nanoparticles synthesized for biodetection studies
EMSL Project ID
10497
Abstract
The research included in this proposal involves the routine analysis of organic ligand-stabilized semiconductor nanoparticles that will serve as the signal transduction element in fluorescence-based biosensors. The semiconductor cores (typically CdSe or CdTe) of the nanoparticles are surrounded by an encapsulating layer of organic molecules which can be analyzed using standard solution-phase proton and carbon-13 NMR techniques. In addition, metallic nanoparticles stabilized by organic ligands that are designed for use in both electrochemical and surface acoustic wave sensors will be analyzed. The purpose of this analysis is to determine the overall purity of the nanoparticle samples allowing for the comparison of organic ligands that are bound to the nanoparticle core to those that are free in solution. Usage of the instrument would be steady but light with a typical sample taking on the order of 5-15 minutes on a 300 MHz instrument.Project Details
Project type
Capability Research
Start Date
2004-10-01
End Date
2006-04-24
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members