FESEM Analysis of Reversible Gels
EMSL Project ID
1905
Abstract
CONFIDENTIAL INFORMATION (PLEASE DO NOT USE ON THE EMSL WEB SITE): We have developed novel polymers based on poly(lactic acid-co-glycolic acid)-poly(ethylene glycol) . These polymers form reversible hydrogels. SEM studies would aid in assesment of the gel structure. We would like to verify the hypothesis of phase separation and micell formation. Aqueous solutions of the novel polymers are free flowing at room temperature and become gels at 370C in a few seconds, indicating promising biomaterials for advanced drug delivery and tissue engineering. The basic principle of sol-to-gel transition is a change in molecular association caused by changes in temperature, pH, and solvent. SEM studies would aid in assesment of the gel structure.
Project Details
Project type
Exploratory Research
Start Date
2000-02-03
End Date
2000-12-31
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Phase Transition of the PLGA-g-PEG Copolymer Aqueous solutions