Soft-Landing of Complex Ions on Surfaces
EMSL Project ID
19594
Abstract
Interaction of ions with surfaces is an area of active fundamental research in surface science relevant to a broad range of other scientific disciplines supported by the DOE Office of Science such as materials science, mass spectrometry, imaging and spectroscopy. The proposed research will specifically focus on fundamental understanding of reactive and non-reactive deposition of hyperthermal (1-100 eV) peptide, protein and polymer ions on organic surfaces under ultrahigh vacuum conditions. Two major processes are dominant for this range of collision energies: reactive and non-reactive scattering of ions and ion loss on the surface as a result of neutralization or soft-landing of projectile ions. SL and a related process of reactive landing (RL) of ions, in which ion is covalently attached to the surface, are unique processes that occur during collisions of low-energy ions with self-assembled monolayer (SAM) surfaces. Our recent studies on fundamental aspects of SL of peptide ions provide solid support for this work.
Project Details
Project type
Large-Scale EMSL Research
Start Date
2006-08-18
End Date
2009-09-30
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Alvarez J, JH Futrell, and J Laskin. 2006. "Soft-Landing of Peptides onto Self-Assembled Monolayer Surfaces." Journal of Physical Chemistry A 110(4):1678-1687. doi:10.1021/jp0555044
Hadjar O, JH Futrell, and J Laskin. 2007. "First Observation of Charge Reduction and Desorption Kinetics of Multiply Protonated Peptides Soft Landed onto Self-Assembled Monolayer Surfaces." Journal of Physical Chemistry C 111(49):18220-18225. doi:10.1021/jp075293y
Hadjar O, P Wang, JH Futrell, Y Dessiaterik, Z Zhu, JP Cowin, MJ Iedema, and J Laskin. 2007. "Design and Performance of a Novel Instrument for Soft-Landing of Biomolecular Ions on Surfaces." Analytical Chemistry 79(17):6566-6574. doi:10.1021/ac070600h
Hu Q, P Wang, and J Laskin. 2010. "Effect of the surface on the secondary structure of soft landed peptide ions." Physical Chemistry Chemical Physics. PCCP 12(39):12802-12810. doi:10.1039/C0CP00825G
Johnson GE, M Lysonski, and J Laskin. 2010. "In Situ Reactivity and TOF SIMS Analysis of Surfaces Prepared by Soft and Reactive Landing of Mass Selected Ions." Analytical Chemistry 82(13):5718-5727. doi:10.1021/ac100734g
Johnson GE, Q Hu, and J Laskin. 2011. "Soft Landing of Complex Molecules on Surfaces." Annual Review of Analytical Chemistry 4(1):83-104. doi:10.1146/annurev-anchem-061010-114028
Laskin J, P Wang, and O Hadjar. 2008. "Soft-Landing of Peptide IOns Onto Self-Assembled Monolayer Surfaces: an Overview." Physical Chemistry Chemical Physics. PCCP 10(8):1079-1090. doi:10.1039/b712710c
Laskin J, P Wang, O Hadjar, JH Futrell, J Alvarez, and RG Cooks. 2007. "Charge Retention by Peptide Ions Soft-Landed onto Self-Assembled Monolayer Surfaces." International Journal of Mass Spectrometry 265(1):237-243.
O. Hadjar, P. Wang, J. H. Futrell, J. Laskin- “Effect of the Surface on Charge Reduction and Desorption Kinetics of Soft Landed Peptide Ions”, J. Am. Soc. Mass Spectrom., 20, 901–906 (2009)
P. Wang and J. Laskin “Surface Modification Using Reactive Landing of Mass-Selected Ions on Surfaces”, book chapter, Ion beams in Nanoscience and Technology, H.J. Whitlow , Y. Zhang, R. Hellborg (Eds.), Springer, 2010
Q. Hu, P. Wang, P.L. Gassman, and J. Laskin “In situ Studies of Soft- and Reactive Landing of Mass-Selected Ions Using Infrared Reflection Absorption Spectroscopy”, Anal. Chem., 81, 7302–7308 (2009)
Wang P, and J Laskin. 2008. "Helical Peptide Arrays on Self-Assembled Monolayer Surfaces Through Soft and Reactive Landing of Mass-Selected Ions." Angewandte Chemie International Edition 47:6678-6680. doi:10.1002/anie.200801366
Wang P, O Hadjar, and J Laskin. 2007. "Covalent Immobilization of Peptides on Self-Assembled Monolayer Surfaces Using Soft-Landing of Mass-Selected Ions." Journal of the American Chemical Society 129:8682-8683.
Wang P, O Hadjar, PL Gassman, and J Laskin. 2008. "Reactive Landing of Peptide Ions on Self-Assembled Monolayer Surfaces: A Alternative Approach for Covalent Immobilization of Peptides on Surfaces." Physical Chemistry Chemical Physics. PCCP 10(11):1512-1522. doi:10.1039/b717617a