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MICROFABRICATION OF ELECTROSPRAY EMITTER ARRAYS FOR IMPROVED SENSITIVITY IN ELECTROSPRAY IONIZATION-MASS SPECTROMETRY


EMSL Project ID
20492

Abstract

Abstract

Proposal attached

Project Details

Project type
Exploratory Research
Start Date
2006-10-04
End Date
2007-10-04
Status
Closed

Team

Principal Investigator

Ryan Kelly
Institution
Brigham Young University

Team Members

Richard Smith
Institution
Pacific Northwest National Laboratory

Keqi Tang
Institution
Pacific Northwest National Laboratory

Related Publications

Coupling Microfluidics with Mass Spectrometry for Sample-Limited Bioanalyses by Ryan T Kelly. Pittcon Conference March 2010, Orlando, FL
Kelly, R. T.; Tang, K.; Irimia, D.; Toner, M.; Smith, R.D. Elastomeric Microchip Electrospray Emitter for Stable Cone-Jet Mode Operation in the Nano-Flow Regime Anal. Chem. 2008, 80, 3824-3831.
Kelly, R. T.; Tang, K.; Irimia, D.; Toner, M.; Smith, R.D. Elastomeric Microchip Electrospray Emitter for Stable Cone-Jet Mode Operation in the Nano-Flow Regime Anal. Chem. 2008, in press.
Oral Presentation at the CMOS Emerging Technologies conference in Whistler, BC, May, 2010
Sun X, RT Kelly, K Tang, and RD Smith. 2010. "Ultrasensitive Nanoelectrospray Ionization-Mass Spectrometry using Poly(dimethylsiloxane) Microchips with Monolithically Integrated Emitters." Analyst 135(9):2296-2302. Available on the Web: DOI 10.1039/c0an00253d
Sun X, RT Kelly, K Tang, and RD Smith. 2011. "Membrane-Based Emitter for Coupling Microfluidics with Ultrasensitive Nanoelectrospray Ionization-Mass Spectrometry." Analytical Chemistry 83(4):5797-5803. doi:10.1021/ac200960h
Sun X, RT Kelly, WF Danielson, III, N Agrawal, K Tang, and RD Smith. 2011. "Hydrodynamic injection with pneumatic valving for microchip electrophoresis with total analyte utilization." Electrophoresis 32(13):1610-1618. doi:10.1002/elps.201000522