(emslcsd4)Graphic presentation of conformational motions of dye-labeled enzyme
EMSL Project ID
2179
Abstract
We have studied the conformation change of enzyme molecules by single molecule spectroscopy by monitoring the energy transfer efficiency of dyes labeled on the enzyme. In additional to spectroscopy study, we would like to visualize the conformational motions of the enzyme by computer. The software Insight II in the graphic lab is prefect for this proposes. The enzyme structures are from Protein Data Bank. They will be modified based on the labeling dye and substrate. The graphic presentation will clearly demonstrate how the enzymatic reactivity is related to the conformation.
Project Details
Project type
Capability Research
Start Date
2001-02-12
End Date
2002-10-01
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members