Structural Genomics of Eukaryotic Model Organisms
EMSL Project ID
2450
Abstract
The primary goal of our pilot project is to develop integrated technologies for high-throughput (htp) protein production and 3D structure determination. These will form key components of the scientific infrastructure required for the next stage of genome research beyond DNA sequencing. Our NESG Consortium has the particular focus of evaluating the role of protein NMR spectroscopy in future Structural Proteomics Centers to be funded by NIH. Our targets include members of large protein families for which no 3D structural information is available. We prioritize protein families with representatives in human and higher eukaryotic genomes because of the important role of these proteins in human health and model organism biology.. We rely heavily on distributed NMR data collection facilities, particularly those at Pacific Northwest National Laboratories.
Project Details
Project type
Capability Research
Start Date
2002-04-01
End Date
2002-11-18
Status
Closed
Released Data Link
Team
Principal Investigator