Solid-State 67Zn NMR of Synthetic Metalloprotein Models
EMSL Project ID
2452b
Abstract
It is the invention of this proposal to describe studies that will be undertaken in order to aid our understanding of the structures and mechanisms of zinc enzymes. Such knowledge will be obtained by preparing and investigating synthetic analogues that are intended to mimic both the structure and function of a zinc enzyme. These analogues will be compared and contrasted with the native protein via spectroscopic and structural methods, in particular through a combination of X-ray, NMR, EZAFS/XANES spectroscopy. Specifically, the collaborative team intends to address the following aims:
Project Details
Project type
Capability Research
Start Date
2004-04-16
End Date
2006-04-21
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Lipton AS, MM Morlok, G Parkin, and PD Ellis. 2008. "67Zn Solid-State NMR Spectroscopy of {[TpBut,Me]Zn(OH2)}[HOB(C6F5)3]. The Importance of the Anion [HOB(C6F5)3]-." Inorganic Chemistry 47(12):5184-5189. doi:10.1021/ic800009b