How Desert Varnish Forms
EMSL Project ID
2500
Abstract
The objective is to see if desert varnish is microbially mediated or an organic process. Desert varnish has not been investigated on a micro scale. Careful characterization of varnish structure, inorganic and organic chemistry, and presence of microbes and/or spores will prove useful in understanding the process of formation. Understanding how varnish forms is important for several reasons: as a biomarker for Martian analogues; understanding iron redox chemistry as influenced by microbes; and as a potential biomineralization process. The approach will be to use XPS, TOF-SIMS, and TEM/SEM to characterize the structure of varnish. If applicable, we'll use the XSW synchrotron. In addition, we might use Auger, Mossbauer, laser desorption, XRD, and RBS.
Project Details
Project type
Exploratory Research
Start Date
2002-04-15
End Date
2005-04-17
Status
Closed
Released Data Link
Team
Principal Investigator
Related Publications
Application of proteomics in the discovery of candidate protein biomarkers in a Diabetes Autoantibody Standardization Program sample subset. Metz TO, Qian W, Jacobs JM, Gritsenko MA, Moore RJ, Polpitiya AD, Monroe ME, Camp DG, Mueller PW, Smith RD. Journal of Proteome Research 2008, 7(2):698-707.
"Characterization of the Human Pancreatic Islet Proteome by Two- Dimensional LC/MS/MS" Metz, T.O., Jacobs, J.M., Gritsenko, M.A., Fontès, G., Qian, W.J., Camp II, D.G., Poitout, V., Smith, R.D. (2006) J. Proteome Res. 5, 3345-3354.
Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets. Alquier T, Peyot M-L, Latour MG, Kebede M, Sorensen CM, Gesta S, Kahn R, Smith RD, Jetton TL, Metz TO, Prentki M, Poitout V. Diabetes 2009, 58:2607-2615.
Ding J, CM Sorensen, N Jaitly, H Jiang, D Orton, ME Monroe, RJ Moore, RD Smith, and T Metz. 2008. "Application of the accurate mass and time tag approach in studies of the human blood lipidome." Journal of Chromatography B 871(2):243-252. doi:10.1016/j.jchromb.2008.04.040
Metz TO. "Application of capillary LC-MS in metabolic fingerprinting studies of type 1 diabetes mellitus." Presented at the 7th Annual "Identifying and Validating Metabolic Markers for Drug Discovery and Clinical Studies" December 4-5 2006, Orlando, FL.
Metz TO, JM Jacobs, MA Gritsenko, G Fontes, W Qian, DG Camp, VJ Poitout, and RD Smith. 2006. "Characterization of the Human Pancreatic Islet Proteome by Two-Dimensional LC/MS/MS." Journal of Proteome Research 5(12):3345-3354.
Metz TO, Q Zhang, JS Page, Y Shen, SJ Callister, JM Jacobs, and RD Smith. 2007. "Future of liquid chromatography-mass spectrometry in metabolic profiling and metabolomic studies for biomarker discovery." Biomarkers in Medicine 1(1):159-185.
Metz, TO, WJ Qian, JM Jacobs, MA Gritsenko, RJ Moore, DG Camp, PW Mueller, and RD Smith. "Identification of biomarkers of type 1 diabetes mellitus utilizing capillary LC-FTICR MS and the accurate mass and time tag (AMT) approach. Presented at the 3rd Annual U.S. HUPO Conference March 4-9 2007, Seattle, WA.
Sorensen, CM, DS Daly, TO Metz, N Jaitly, SJ Callister, ME Monroe, JS Zimmer, RJ Moore, and RD Smith. "Screening of LC-MS-based metabolic profiling data utilizing statistical modeling to identify candidate biomarkers." Presented at the 55th Annual ASMS Conference on Mass Spectrometry, June 3-7 2007, Indianapolis, IN
Sorensen CM, J Ding, Q Zhang, T Alquier, R Zhao, PW Mueller, RD Smith, and TO Metz. 2010. "Perturbations in the Lipid Profile of Individuals with Newly Diagnosed Type 1 Diabetes Mellitus: Lipidomics Analysis of a Diabetes Antibody Standardization Program Sample Subset." Clinical Biochemistry 43(12):948-956.
Testing the Role of Silicic Acid and Bioorganic Materials in the Formation of Rock Coatings