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Magnetic Resonance Microscopy of Ozone-Induced Lung Injury


EMSL Project ID
25684

Abstract

The goal for this project is to develop a three-dimensional (3D), geometric database that describes the remodeling of respiratory airways in Rhesus monkeys following ozone challenge.

Project Details

Project type
Large-Scale EMSL Research
Start Date
2007-06-01
End Date
2009-09-30
Status
Closed

Team

Principal Investigator

Kevin Minard
Institution
Pacific Northwest National Laboratory

Team Members

Richard Corley
Institution
Pacific Northwest National Laboratory

Richard Jacob
Institution
Pacific Northwest National Laboratory

Related Publications

3D MRI of non-Gaussian 3He gas diffusion in the rat lung Richard E. Jacob a,-, Gernot Laicher b, Kevin R. Minard a a Pacific Northwest National Laboratory, 902 Battelle Blvd. MS P7-58, Richland, WA 99352, USA b University of Utah, Salt Lake City, UT 84112, USA
S.A. Carey, K.R. Minard, J.S. Kimbell, L.L. Trease, C.G. Plopper, R.A. Corley, E.M. Postlethwait, and J.R. Harkema, Three-Dimensional Mapping of Ozone-Induced Lesions in the Nasal Airways of Monkeys Using Magnetic Resonance Imaging and Morphometric Techniques, Toxicologic Pathology, 35(1): 27-40 (2007).