A proteomic perspective of biodiversity
EMSL Project ID
27790
Abstract
- The relationship between biodiversity and ecosystem stability has become a central focus for ecologists, particularly in the face of environmental stresses and global climate change. Although biodiversity and ecosystem stability has received a large amount of attention, characterization of ecosystem stability remains somewhat elusive. Biodiversity is generally defined in terms of number of species or genotypes, their functional traits, and their interactions; however in principle, the definition of biodiversity extends beyond species and genotype to the genome and proteome level. Recent studies have narrowed the gap between genome biology and ecology by examining genomic elements in an ecosystem context. We propose a proteomic application of ecological principles to model the stability of environmentally relevant bacterial strains to osmotic-induced stress. The objective of this proposal is to correlate genome size (biodiversity) to the stress induced proteome of two closely-related strains (Shewanella oneidensis MR-1 and Shewanella amazonensis). We seek to answer the question; "Does genome size and the expressed proteome correspond to increased ecological stability (a composite of resistance and resilience) at the organism level."
Project Details
Project type
Exploratory Research
Start Date
2008-01-01
End Date
2009-01-04
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Parnell JJ, SJ Callister, G Rompato, CD Nicora, L Pasa-Tolic, A Williamson, and ME Pfrender. 2011. "Time-course analysis of the Shewanella amazonensis SB2B proteome in response to osmotic shock." Proteomics 1(25):, doi:10.1038/srep00025