Proteomic Characterization of Yersinia pestis
EMSL Project ID
3201
Abstract
Proteomic profiling of pathogenic microbes: Expand the knowledge base of the threat to enable better intervention and treatment after exposure. This project will: 1) Leverage the state of the art proteomics technology currently being developed at PNNL to specifically focus on Yersina pestis. 2) Provide a greater understanding of the life cycle, virulence and pathogenesis of Y. pestis while at the same time providing highly distinctive and specific potential biomarkers for an integrated mass spectrometry based detection system and 3) Build a vital bridge across the gap between two established program thrusts: the determination of DNA signatures and the characterization of protein structure by pinpointing important protein targets.
Project Details
Project type
Exploratory Research
Start Date
2002-12-05
End Date
2005-10-24
Status
Closed
Released Data Link
Team
Principal Investigator