Immobilized Enzymes for Bioremediation and Biosensing - Armored Enzyme Nanoparticles for Remediation of Subsurface Contaminants (JB's EMSP Project - 43946) and Nanoscale Enzyme Reactors (JB's DARPA Project - 49090)
EMSL Project ID
3241
Abstract
Immobilized enzyme systems, stabilizing the enzyme activity, will be tested for the purposes of bioremediation and biosensing. Stabilization of enzyme activity is a critical advance that is required in order to use enzymes effectively for the remediation and/or biosensing of organic compounds in various environments. Various techniques of enzyme immobilizaiton will be investigated and compared, beginning with a protease (alpha-chymotrypsin) and tyrosinase, both of which are commercially available. We may also use a haloalkane dehalogenase for the degradation of trichloroethylene (TCE) and other chlorinated hydrocarbons of interest to DOE.
Project Details
Project type
Capability Research
Start Date
2003-01-16
End Date
2006-01-22
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members