TEM and XPS analysis of ligand-functionalized semiconductor quantum dots used in biodetection studies
EMSL Project ID
3895
Abstract
The research included in this proposal involves the routine TEM and XPS analysis of functionalized semiconductor nanoparticles (primarily CdSe) that will serve as the signal transduction element in fluorescence-based biosensors. The luminescent properties of these materials depend intimately on their size and shape; therefore, in order to fully characterize a sample for a given sensor application, it is necessary to examine them with techniques such as TEM and XPS. TEM will allow us to directly image the individual nanoparticle cores to determine their individual shape and size. Further, this will allow for an accurate correlation between the optical properties of the nanoparticle sample and the morphology of the individual nanoparticle cores to be generated. Usage of the instruments would be steady but light with a typical sample set taking between 1-3 hours of time on each system with only 3-4 samples per month.
Project Details
Project type
Exploratory Research
Start Date
2003-07-30
End Date
2006-07-31
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Fernandez CA, EM Hoppes, JG Bekhazi, CM Wang, RJ Wiacek, MG Warner, GE Fryxell, JT Bays, and RS Addleman. 2008. "Tuning and Quantifying the Dispersibility of Gold Nanocrystals in Liquid and Supercritical Solvents ." Journal of Physical Chemistry C 112(36):13947-13957. doi:10.1021/jp8038237
Mouser PJ, MJ Wilkins, DF Smith, KH Williams, L Pasa-Tolic, and PE Long. 2011. "Molecular Characterization and Utilization of Dissolved Organic Matter by Microbial Communities Indigenous to a Uranium-Contaminated Aquifer." PNNL-SA-84799, Pacific Northwest National Laboratory, Richland, WA.