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Hydrogen Bond Networks


EMSL Project ID
42590

Abstract

Nature employs hydrogen bonds to organize biomolecular structures and optimize the catalytic ability of enzymes. The effects of hydrogen bond networks are relatively unknown and will be explored by low temperature negative ion photoelectron spectroscopy (a unique resource available at EMSL) and high-level computations. This will facilitate the development of novel hydrogen bond acids and catalysts for synthetic purposes. It will also provide new insights into biological processes including enzyme-catalyzed reactions.

Project Details

Project type
Exploratory Research
Start Date
2011-02-07
End Date
2012-02-12
Status
Closed

Team

Principal Investigator

Steven Kass
Institution
University of Minnesota

Team Members

Jacob Schmidt
Institution
University of Minnesota

Xuebin Wang
Institution
Pacific Northwest National Laboratory

Lai-Sheng Wang
Institution
Brown University

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