Hydrogen Bond Networks
EMSL Project ID
42590
Abstract
Nature employs hydrogen bonds to organize biomolecular structures and optimize the catalytic ability of enzymes. The effects of hydrogen bond networks are relatively unknown and will be explored by low temperature negative ion photoelectron spectroscopy (a unique resource available at EMSL) and high-level computations. This will facilitate the development of novel hydrogen bond acids and catalysts for synthetic purposes. It will also provide new insights into biological processes including enzyme-catalyzed reactions.
Project Details
Project type
Exploratory Research
Start Date
2011-02-07
End Date
2012-02-12
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Molecular recognition: preparation and characterization of two tripodal anion receptors
Shokri A, S Deng, XB Wang, and SR Kass. 2014. "Molecular Recognition: Preparation and Characterization of Two Tripodal Anion Receptors." Organic Chemistry Frontiers 1(1):54-61. doi:10.1039/C3QO00009E
Characterization of a Saturated and Flexible Aliphatic Polyol Anion Receptor
Shokri A, JC Schmidt, XB Wang, and SR Kass. 2012. "Characterization of a Saturated and Flexible Aliphatic Polyol Anion Receptor." Journal of the American Chemical Society 134(41):16944-16947. doi:10.1021/ja3075456
Electron-Withdrawing Trifluoromethyl Groups in Combination with Hydrogen Bonds in Polyols: Brønsted Acids, Hydrogen-Bond Catalysts, and Anion Receptors
Shokri A, XB Wang, and SR Kass. 2013. "Electron-Withdrawing Trifluoromethyl Groups in Combination with Hydrogen Bonds in Polyols: Brønsted Acids, Hydrogen-Bond Catalysts, and Anion Receptors." Journal of the American Chemical Society 135(25):9525-9530. doi:10.1021/ja4036384
Hydrogen Bonded Arrays: The Power of Multiple Hydrogen Bonds
Shokri A, JC Schmidt, XB Wang, and SR Kass. 2012. "Hydrogen Bonded Arrays: The Power of Multiple Hydrogen Bonds." Journal of the American Chemical Society 134(4):2094-2099. doi:10.1021/ja2081907