Skip to main content

Biological Systems Interactions


EMSL Project ID
47754

Abstract

SPECIFIC AIMS: The overall objective of the proposed research is to acquire a predictive understanding of how microbial interactions impart stability, fitness, and functional efficiency to microbial communities. These systems include those that carry out critical ecosystem services such as carbon fixation and biogeochemical cycling of nutrients and metals or that are being harnessed as engineered systems for DOE mission applications in bioenergy or carbon sequestration. The proposed work will be in support of PNNL’s Fundamental Scientific Focus Area (FSFA) whose overarching objective is the development of an understanding of unifying principles that couple these complex interactions and interdependencies between members of microbial communities within differing environments. The specific aims include defining:
1) Discover and characterize fundamental relationships between primary producers (autotrophs) and consumers (heterotrophs);
2) Understand the metabolic interactions between taxa that establish the structure and composition of the communities;
3) Delineate how interactions change temporally and spatially as a function of environmental perturbation and genomic evolution;
4) Determine how populations sense and respond to light and O2 and have devised specialized adaptations that allow its members to tolerate associated oxidative stress.

Project Details

Start Date
2012-12-20
End Date
2013-10-30
Status
Closed

Team

Principal Investigator

James Fredrickson
Institution
Pacific Northwest National Laboratory

Co-Investigator(s)

Margaret Romine
Institution
Pacific Northwest National Laboratory

Team Members

Thomas Metz
Institution
Pacific Northwest National Laboratory

Mary Lipton
Institution
Environmental Molecular Sciences Laboratory