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Top-down proteomics analysis to identify intact bioactive proteoforms in commercial cellulase cocktail for crystalline cellulose degradation


EMSL Project ID
48510

Abstract

This is a rapid access proposal to apply the cutting-edge top-down proteomics capability in EMSL to identify bioactive proteoforms present in commercial cellulase enzyme for crystalline cellulose degradation. The protein samples have already been prepared and are waiting for analysis. We anticipate that such experimental results will provide direct evidences to support a manuscript in preparation (we expect to submit this manuscript to a chemical/biology journal in two months). Furthermore, we expect that the results from the proposed study will serve as preliminary data for a new proposal that we are submitting to EMSL later this year.

Project Details

Project type
Limited Scope
Start Date
2014-06-18
End Date
2014-08-18
Status
Closed

Team

Principal Investigator

Xiao Zhang
Institution
Washington State University Tri-Cities