Understanding conversion of biomass-derived carbon into lipids and terpenoids in the oleaginous yeast Rhodosporidium toruloides
EMSL Project ID
49515
Abstract
The objective of this proposal is to understand how biomass-derived carbon is converted into lipids and terpenoids in the oleaginous and carotenogenic yeast Rhodosporidium toruloides. We will carry out a detailed systems biology-level study of wild type and mutant strains using a combination of multi-omic technologies and high resolution microscopy methods. Our goal is to integrate data from multiple experimental approaches to create a comprehensive understanding of biomass-derived carbon conversion into lipids and terpenoids and determine how carbon flux is regulated at the transcriptional and post-transcriptional levels. This project will provide a critical knowledgebase that will enable the development of R. toruloides into a novel metabolic engineering platform organism for the co-conversion of biomass-derived polysaccharide and lignin degradation products into biofuels and bioproducts.
Project Details
Project type
FICUS Research
Start Date
2016-10-01
End Date
2018-09-30
Status
Closed
Released Data Link
Team
Principal Investigator
Co-Investigator(s)
Team Members