Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'
EMSL Project ID
49531
Abstract
Abstract
Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'
Project Details
Start Date
2016-07-11
End Date
2018-09-30
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Ahmad R., C.D. Nicora, A.K. Shukla, R.D. Smith, W. Qian, and A.Y. Liu. 2016. "An efficient method for native protein purification in the selected range from prostate cancer tissue digests." Chinese Clinical Oncology 5, no. 6:78. PNNL-SA-123158. doi:10.21037/cco.2016.12.03
Attah I.K., G. Nagy, V. Garimella, R.V. Norheim, G.A. Anderson, Y.M. Ibrahim, and R.D. Smith. 2019. "Traveling wave-based electrodynamic switch for concurrent dual polarity ion manipulations in Structures for Lossless Ion Manipulations." Analytical Chemistry 91. PNNL-SA-147653. doi:10.1021/acs.analchem.9b03987
Attah I.K., V. Garimella, I.K. Webb, G. Nagy, R.V. Norheim, C.E. Schimelfenig, and Y.M. Ibrahim, et al. 2019. "Dual Polarity Ion Confinement and Mobility Separations." Journal of the American Society for Mass Spectrometry 30, no. 6:967-976. PNNL-SA-146246. doi:10.1007/s13361-019-02138-1
Baker E.M., R. Wojcik, I.K. Webb, V. Garimella, S.A. Prost, Y.M. Ibrahim, and R.D. Smith. 2017. "Lipid and Glycolipid Isomer Analyses Using Ultra-high Resolution Ion Mobility Spectrometry Separations." International Journal of Molecular Sciences 18, no. 1:183. PNNL-SA-122274. doi:10.3390/ijms18010183
Bakhanova E.V., R. Wu, W. Wang, R. Yan, Y. Chen, S. French, and C. Llorente, et al. 2018. "Pyroptosis by Caspase11/4-Gasdermin-D Pathway in Alcoholic Hepatitis." Hepatology 67, no. 5:1737-1753. PNNL-SA-130597. doi:10.1002/hep.29645
Bilbao Pena A., B.C. Gibbons, G.W. Slysz, K.L. Crowell, M.E. Monroe, Y.M. Ibrahim, and R.D. Smith, et al. 2018. "An Algorithm to Correct Saturated Mass Spectrometry Ion Abundances for Enhanced Quantitation and Mass Accuracy in Omic Studies." International Journal of Mass Spectrometry 427. PNNL-SA-126312. doi:10.1016/j.ijms.2017.11.003
Burnum-Johnson K.E., J.E. Kyle, A.J. Eisfeld, C.P. Casey, K.G. Stratton, J.F. Gonzalez, and F. Habyarimana, et al. 2017. "MPLEx: A method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling." Analyst 142, no. 3:442-448. PNNL-SA-116063. doi:10.1039/c6an02486f
Causon T J,Zheng X ,Kurulugama Lekamlage R T,Rennie E E,Baker E M,Smith R D,McLean J ,Hann S ,Fjeldsted J C,May J C,Mairinger T ,Stow S 2017. "An Interlaboratory Evaluation of Drift Tube Ion Mobility?Mass" Analytical Chemistry 89(17):9048–9055. 10.1021/acs.analchem.7b01729
Chouinard C.D., G. Nagy, I.K. Webb, T. Shi, E.M. Baker, S.A. Prost, and T. Liu, et al. 2018. "Improved Sensitivity and Separations for Phosphopeptides using Online LC Coupled with Structures for Lossless Ion Manipulations (SLIM) IM-MS." Analytical Chemistry 90, no. 18:10889-10896. PNNL-SA-135107. doi:10.1021/acs.analchem.8b02397
Chouinard C.D., G. Nagy, I.K. Webb, V. Garimella, E.M. Baker, Y.M. Ibrahim, and R.D. Smith. 2018. "Rapid Ion Mobility Separations of Bile Acid Isomers Using Cyclodextrin Adducts and Structures for Lossless Ion Manipulations." Analytical Chemistry 90, no. 18:11086-11091. PNNL-SA-136059. doi:10.1021/acs.analchem.8b02990
Chouinard C.D., G. Nagy, R.D. Smith, and E.M. Baker. 2019. "Ion Mobility-Mass Spectrometry in Metabolomic, Lipidomic, and Proteomic Analyses." In Comprehensive Analytical Chemistry. 123-159. PNNL-SA-137883. doi:10.1016/bs.coac.2018.11.001
Deng L, IK Webb, VBS Garimella, AM Hamid, X Zheng, RV Norheim, SA Prost, GA Anderson, JA Sandoval, EM Baker, YM Ibrahim, and RD Smith. 2017. "Serpentine Ultralong Path with Extended Routing (SUPER) High Resolution Traveling Wave Ion Mobility-MS using Structures for Lossless Ion Manipulations." Analytical Chemistry 89(8):4628–4634. doi:10.1021/acs.analchem.7b00185
Deng L., V. Garimella, A.M. Hamid, I.K. Webb, I.K. Attah, R.V. Norheim, and S.A. Prost, et al. 2017. "Compression Ratio Ion Mobility Programming (CRIMP) Accumulation and Compression of Billions of Ions for Ion Mobility-Mass Spectrometry Using Traveling Waves in Structures for Lossless Ion Manipulations (SLIM)." Analytical Chemistry 89, no. 12:6432-6439. PNNL-SA-123357. doi:10.1021/acs.analchem.7b00189
Dickinson M., L.N. Anderson, B.M. Webb-Robertson, J.R. Hansen, R.D. Smith, A.T. Wright, and K. Hybiske. 2018. "Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites." bioRxiv. PNNL-SA-132851. doi:10.1101/285106.
Dickinson M., L.N. Anderson, B.M. Webb-Robertson, J.R. Hansen, R.D. Smith, A.T. Wright, and K. Hybiske. 2019. "Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites." PLoS Pathogens 15, no. 4:Article Number e1007698. PNNL-SA-132851. doi:10.1371/journal.ppat.1007698
Duan J, MJ Gaffrey, and W Qian. 2017. "Quantitative Proteomic Characterization of Redox-dependent Post-translational Modifications on Protein Cysteines." Molecular Biosystems 13(5):816-829. doi:10.1039/c6mb00861e
Eisfeld A.J., P. Halfmann, J.P. Wendler, J.E. Kyle, K.E. Burnum-Johnson, Z. Peralta, and T. Maemura, et al. 2017. "Multi-platform 'Omics Analysis of Human Ebola Virus Disease Pathogenesis." Cell Host & Microbe 22, no. 6:817-829. PNNL-SA-120881. doi:10.1016/j.chom.2017.10.011
Garabedian A., P. Benigni, C. Ramirez, E.M. Baker, T. Liu, R.D. Smith, and F. Fernandez-Lima. 2018. "Towards Discovery and Targeted Peptide Biomarker Detection Using nanoESI-TIMS-TOF MS." Journal of the American Society for Mass Spectrometry 29, no. 5:817-826. PNNL-SA-129610. doi:10.1007/s13361-017-1787-8
Garimella VBS, AM Hamid, L Deng, YM Ibrahim, IK Webb, EM Baker, SA Prost, RV Norheim, GA Anderson, and RD Smith. 2016. "Squeezing of Ion Populations and Peaks in Traveling Wave Ion Mobility Separations and Structures for Lossless Ion Manipulations using Compression Ratio Ion Mobility Programming." Analytical Chemistry 88(23):11877-11885. doi:10.1021/acs.analchem.6b03660
Garimella VBS, IK Webb, A Prabhakaran Nair Syamala Amma, IK Attah, YM Ibrahim, and RD Smith. 2017. "DESIGN OF TW-SLIM FOR DUAL POLARITY CONFINEMENT, TRANSPORT AND REACTIONS." Journal of the American Society for Mass Spectrometry 28(7):1442-1449. doi:10.1007/s13361-017-1680-5
Garimella V., G. Nagy, Y.M. Ibrahim, and R.D. Smith. 2019. "Opening new paths for biological applications of ion mobility - Mass spectrometry using structures for lossless ion manipulations." Trends in Analytical Chemistry. TrAC 116. PNNL-SA-140349. doi:10.1016/j.trac.2019.04.021
Gibbons B.C., T.L. Fillmore, Y. Gao, R.J. Moore, T. Liu, E.S. Nakayasu, and T.O. Metz, et al. 2019. "Rapidly Assessing the Quality of Targeted Proteomics Experiments through Monitoring Stable-Isotope Labeled Standards." Journal of Proteome Research 18, no. 2:694-699. PNNL-SA-137457. doi:10.1021/acs.jproteome.8b00688
Hamid A.M., A. Prabhakaran Nair Syamala Amma, V. Garimella, Y.M. Ibrahim, and R.D. Smith. 2018. "Characterization of applied fields for ion mobility in traveling wave based structures for lossless ion manipulations (SLIM)." International Journal of Mass Spectrometry 430. PNNL-SA-127372. doi:10.1016/j.ijms.2018.03.006
Ibrahim Y.M., A.M. Hamid, L. Deng, V. Garimella, I.K. Webb, E.M. Baker, and R.D. Smith. 2017. "New Frontiers for Mass Spectrometry based upon Structures for Lossless Ion Manipulations." Analyst 142, no. 7:1010-1021. PNNL-SA-123137. doi:10.1039/C7AN00031F
Kedia K., J.P. Wendler, E.M. Baker, K.E. Burnum-Johnson, L.G. Jarsberg, K.G. Stratton, and A.T. Wright, et al. 2018. "Application of multiplexed ion mobility spectrometry towards the identification of host protein signatures of treatment effect in pulmonary tuberculosis." Tuberculosis 112. PNNL-SA-137966. doi:10.1016/j.tube.2018.07.005
Kramer P.A., J. Duan, M.J. Gaffrey, A.K. Shukla, L.L. Wang, T. Bammler, and W. Qian, et al. 2018. "Fatiguing Contractions Increase Protein S-Glutathionylation Occupancy in Mouse Skeletal Muscle." Redox Biology 17. PNNL-SA-135523. doi:10.1016/j.redox.2018.05.011
Kyle JE, CP Casey, KG Stratton, EM Zink, YM Kim, X Zheng, ME Monroe, KK Weitz, KJ Bloodsworth, DJ Orton, YM Ibrahim, RJ Moore, C Lee, C Pedersen, ES Orwoll, RD Smith, KE Burnum-Johnson, and EM Baker. 2017. "Comparing Identified and Statistically Significant Lipids and Metabolites in 15-Year Old Serum and Dried Blood Spot Samples for Longitudinal Studies." Rapid Communications in Mass Spectrometry 31(5):447-456. doi:10.1002/rcm.7808
Kyle JE, NA Aly, X Zheng, KE Burnum-Johnson, RD Smith, and EM Baker. 2018. "Evaluating Lipid Mediator Structural Complexity Using Ion Mobility Spectrometry." Bioanalysis 10(5):279-289. doi:10.4155/bio-2017-0245
Lobanov A.V., S.M. Heaphy, A.A. Turanov, M.V. Gerashchenko, S. Pucciarelli, R.R. Devaraj, and F. Xie, et al. 2017. "Position-dependent termination and widespread obligatory frameshifting in Euplotes translation." Nature Structural & Molecular Biology 24, no. 1:61-68. PNNL-SA-123907. doi:10.1038/nsmb.3330
Matsushita K., K. Golgotiu, D.J. Orton, R.D. Smith, K.D. Rodland, P.D. Piehowski, and M.P. Hutchens. 2018. "Micropuncture of Bowman's Space in Mice Facilitated by 2 Photon Microscopy." Journal of Visual Experiments 140. PNNL-SA-137928. doi:10.3791/58206
Menachery V.D., A. Schafer, K.E. Burnum-Johnson, H.D. Mitchell, A.J. Eisfeld-Fenney, K.B. Walters, and C.D. Nicora, et al. 2018. "MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape." Proceedings of the National Academy of Sciences of the United States of America 115, no. 5:E1012-E1021. PNNL-SA-126254. doi:10.1073/pnas.1706928115
Metz T.O., E.M. Baker, E.L. Schymanski, R.S. Renslow, D.G. Thomas, T.J. Causon, and I.K. Webb, et al. 2017. "Integrating Ion Mobility Spectrometry into Mass Spectrometry-based Exposome Measurements: What Can It Add and How Far Can It Go?." Bioanalysis 9, no. 1:81-98. PNNL-SA-121158. doi:10.4155/bio-2016-0244
Moghieb A.M., L. Tesfay, S. Nie, M.A. Gritsenko, T.L. Fillmore, J.M. Jacobs, and R.D. Smith, et al. 2019. "A Targeted Mass Spectrometric Assay for Reliable Sensitive Hepcidin Quantification." Scientific Reports 9. PNNL-SA-138022. doi:10.1038/s41598-019-43756-9
Nagy G., C.D. Chouinard, I.K. Attah, I.K. Webb, V. Garimella, Y.M. Ibrahim, and E.M. Baker, et al. 2019. "Distinguishing Enantiomeric Amino Acids with Chiral Cyclodextrin Adducts and Structures for Lossless Ion Manipulations." Electrophoresis 39, no. 24:3148–3155. PNNL-SA-136376. doi:10.1002/elps.201800294
Nagy G., D. Velickovic, R.K. Chu, A.A. Carrell, D.J. Weston, Y.M. Ibrahim, and C.R. Anderton, et al. 2018. "Towards Resolving the Spatial Metabolome with Unambiguous Molecular Annotations in Complex Biological Systems by Coupling Mass Spectrometry Imaging with Structures for Lossless Ion Manipulations." Chemical Communications. PNNL-SA-138045. doi:10.1039/C8CC07482H
Nagy G., I.K. Attah, V. Garimella, Y.M. Ibrahim, E.M. Baker, and R.D. Smith. 2018. "Unraveling the Isomeric Heterogeneity of Glycans: Ion Mobility Separations in Structures for Lossless Ion Manipulations." Chemical Communications 54, no. 83:11701-11704. PNNL-SA-137134. doi:10.1039/C8CC06966B
Nagy G., K. Kedia, I.K. Attah, V. Garimella, Y.M. Ibrahim, V.A. Petyuk, and R.D. Smith. 2019. "Separation of ß-Amyloid Tryptic Peptide Species with Isomerized and Racemized L-Aspartic Residues with Ion Mobility in Structures for Lossless Ion Manipulations." Analytical Chemistry 91, no. 7:4374-4380. PNNL-SA-138885. doi:10.1021/acs.analchem.8b04696
Nagy G., K. Kedia, I.K. Attah, V. Garimella, Y.M. Ibrahim, V.A. Petyuk, and R.D. Smith. 2019. "Separation of ß-Amyloid Tryptic Peptide Species with Isomerized and Racemized L-Aspartic Residues with Ion Mobility in Structures for Lossless Ion Manipulations." Analytical Chemistry. PNNL-SA-138885. doi:10.1021/acs.analchem.8b04696.
Nielson C., J.M. Jacobs, and E.S. Orwoll. 2019. "Proteomic studies of bone and skeletal health outcomes." Bone 126. PNNL-SA-147327. doi:10.1016/j.bone.2019.03.032
Nielson C ,Jones K ,Chun R F,Jacobs J M,Wang Y ,Hewison M ,Adams J S,Swanson C ,Lee C ,Vanderschueren D ,Pauwels S ,Prentice A ,Smith R D,Shi T ,Gao Y ,Schepmoes A A,Zmuda J M,Lapidus J ,Cauley J A,Bouillon R ,Schoenmakers I ,Orwoll E S 2016. "Free 25-hydroxyvitamin D: impact of vitamin D" Journal of Clinical Endocrinology and Metabolism 101(5):2226–2234. 10.1210/jc.2016-1104
Nielson C, J Wiedrick, J Shen, JM Jacobs, EM Baker, A Baraff, PD Piehowski, C Lee, A Baratt, VA Petyuk, SK Mcweeney, JY Lim, DC Bauer, NE Lane, PM Cawthon, RD Smith, J Lapidus, and ES Orwoll. 2017. "Identification of Hip BMD Loss and Fracture Risk Markers Through Population-Based Serum Proteomics." Journal of Bone and Mineral Research 32(7):1559-1567. doi:10.1002/jbmr.3125
Nie S., T. Shi, T.L. Fillmore, A.A. Schepmoes, H.M. Brewer, Y. Gao, and E. Song, et al. 2017. "Deep-dive Targeted Quantification for Ultrasensitive Analysis of Proteins in Nondepleted Human Blood Plasma/Serum and Tissues." Analytical Chemistry 89, no. 17:9139-9146. PNNL-SA-126297. doi:10.1021/acs.analchem.7b01878
Olah M., E. Patrick, A. Villani, J. Xu, C. White, K. Ryan, and P.D. Piehowski, et al. 2018. "A transcriptomic atlas of aged human microglia." Nature Communications 9. PNNL-SA-134273. doi:10.1038/s41467-018-02926-5
Ortega C., A. Frando, B.M. Webb-Robertson, L.N. Anderson, N. Fleck, E.L. Flannery, and M. Fishbaugher, et al. 2018. "A global survey of ATPase activity in Plasmodium falciparum asexual blood stages and gametocytes." Molecular and Cellular Proteomics 17, no. 1:111-120. PNNL-SA-121236. doi:10.1074/mcp.RA117.000088
Orton D.J., M.M. Tfaily, R.J. Moore, B.L. Lamarche, X. Zheng, T.L. Fillmore, and R.K. Chu, et al. 2018. "A Customizable Flow Injection System for Automated, High Throughput and Time Sensitive Ion Mobility Spectrometry and Mass Spectrometry Measurements." Analytical Chemistry 90, no. 1:737-744. PNNL-SA-128111. doi:10.1021/acs.analchem.7b02986
Orwoll ES, J Wiedrick, JM Jacobs, EM Baker, PD Piehowski, VA Petyuk, Y Gao, T Shi, RD Smith, DC Bauer, SR Cummings, C Nielson, and J Lapidus. 2018. "High throughput serum proteomics for the identification of protein biomarkers of mortality in older men." Aging Cell 17(2):UNSP e12717. doi:10.1111/acel.12717
Petyuk V.A., R.R. Chang, M. Ramirez Restrepo, N.B. Bechmann, M.Y. Henrion, P.D. Piehowski, and K. Zhu, et al. 2018. "The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target." Brain 141, no. 9:2721–2739. PNNL-SA-133886. doi:10.1093/brain/awy215
Poad BL, X Zheng, TA Mitchell, RD Smith, EM Baker, and SJ Blanksby. 2018. "Online ozonolysis combined with ion mobility-mass spectrometry provides a new platform for lipid isomer analyses." Analytical Chemistry 90(2):1292-1300. doi:10.1021/acs.analchem.7b04091
Prabhakaran Nair Syamala Amma A, AM Hamid, VBS Garimella, BR Valenzuela, RG Ewing, YM Ibrahim, and RD Smith. 2018. "A Hybrid Constant and Oscillatory Field Ion Mobility Analyzer in Structures for Lossless Ion Manipulations." Journal of the American Society for Mass Spectrometry 29(2):342-351. doi:10.1007/s13361-017-1841-6
Qian W. 2018. "Mass spectrometry-based proteomics for systems-level characterization of biological responses to engineered nanomaterials." Analytical and Bioanalytical Chemistry 410, no. 24:6067-6077. PNNL-SA-133275. doi:10.1007/s00216-018-1168-6
Qiu J, K Yu, X Fei, Y Liu, ES Nakayasu, PD Piehowski, JB Shaw, K Puvar, C Das, X Liu, and ZQ Luo. 2017. "A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination." Cell Research 27(7):865-881. doi:10.1038/cr.2017.66
Schwartz J.B., C. Gallagher, R. Jorde, V. Berg, J. Walsh, R. Eastell, and A.L. Evans, et al. 2018. "Determination of free 25(OH)D concentrations and their relationships to total 25(OH)D in multiple clinical populations." The Journal of Clinical Endocrinology and Metabolism 103, no. 9:3278–3288. PNNL-SA-138870. doi:10.1210/jc.2018-00295
Shi T., M.J. Gaffrey, T.L. Fillmore, C.D. Nicora, L. Yi, A.K. Shukla, and H. Wiley, et al. 2018. "Facile carrier-assisted targeted mass spectrometric approach for single-cell proteomics analysis." Nature Methods. PNNL-SA-130600. doi:10.1038/s42003-018-0107-6
Shi T., S. Quek, Y. Gao, C.D. Nicora, S. Nie, T.L. Fillmore, and T. Liu, et al. 2017. "Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins." Oncotarget 8, no. 60:101887-101898. PNNL-SA-128413. doi:10.18632/oncotarget.21710
Smith RD, I Dhondt, VA Petyuk, HM Brewer, GG Depuydt, BP Braeckman, and S Bauer. 2017. "Changes of Protein Turnover in Aging Caenorhabditis elegans." Molecular & Cellular Proteomics. MCP 16:1621-1633. doi:10.1074/mcp.RA117.000049
Stoddard E.G., B.J. Killinger, R.N. Nair, N.C. Sadler, R.F. Volk, S.O. Purvine, and A.K. Shukla, et al. 2017. "Activity-Based Probes for Isoenzyme- and Site-Specific Functional Characterization of Glutathione S- Transferases." Journal of the American Chemical Society 139, no. 45:16032-16035. PNNL-SA-127421. doi:10.1021/jacs.7b07378
Wang S., F. Yang, V.A. Petyuk, A.K. Shukla, M.E. Monroe, M.A. Gritsenko, and K.D. Rodland, et al. 2017. "Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease." The Journal of Pathology 243, no. 1:78-88. PNNL-SA-119241. doi:10.1002/path.4929
Wojcik R., G. Nagy, I.K. Attah, I.K. Webb, V. Garimella, K.K. Weitz, and A.L. Hollerbach, et al. 2019. "SLIM Ultrahigh Resolution Ion Mobility Spectrometry Separations of Isotopologues and Isotopomers Reveal Mobility Shifts due to Mass Distribution Changes." Analytical Chemistry 91, no. 18:11952-11962. PNNL-SA-147394. doi:10.1021/acs.analchem.9b02808
Yi L, PD Piehowski, T Shi, RD Smith, and W Qian. 2017. "Advances in Microscale Separations towards Nanoproteomics Applications." Journal of Chromatography A. 1523:40-48. doi:10.1016/j.chroma.2017.07.055
Yi L., T. Shi, M.A. Gritsenko, C. Chan, T.L. Fillmore, B.M. Hess, and A.C. Swensen, et al. 2018. "Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway." Analytical Chemistry 90, no. 8:5256-5263. PNNL-SA-131519. doi:10.1021/acs.analchem.8b00071
Yu L., V.A. Petyuk, C. Gaiteri, S. Mostafavi, T. Young-Pearse, R.C. Shah, and A. Buchman, et al. 2018. "Targeted Brain Proteomics Uncover Multiple Pathways to Alzheimer’s Dementia." Annals of Neurology 84, no. 1:78-88. PNNL-SA-136156. doi:10.1002/ana.25266
Yumi Kwon, Paul D. Piehowski, Rui Zhao, Ryan L. Sontag, Ronald J. Moore, Kristin E. Burnum-Johnson, Richard D. Smith, Wei-Jun Qian, Ryan T. Kelly, Ying Zhu. 2022. "Hanging drop sample preparation improves sensitivity of spatial proteomics." Lab on a Chip 22 (15):2869-2877. https://doi.org/10.1039/d2lc00384h
Zheng X., K.T. Dupuis, N.A. Aly, Y. Zhou, F.B. Smith, K. Tang, and R.D. Smith, et al. 2018. "Utilizing Ion Mobility Spectrometry and Mass Spectrometry for the Analysis of Polycyclic Aromatic Hydrocarbons, Polychlorinated Biphenyls, Polybrominated Diphenyl Ethers and Their Metabolites." Analytical Chimica Acta 1037. PNNL-SA-130591. doi:10.1016/j.aca.2018.02.054
Zheng X, L Deng, EM Baker, YM Ibrahim, VA Petyuk, and RD Smith. 2017. "Distinguishing D- and L-Aspartic and Isoaspartic Acids in Amyloid ? Peptides with Ultrahigh Resolution Ion Mobility Spectrometry." Chemical Communications 53(56):7913-7916. doi:10.1039/C7CC03321D
Zheng X., N.A. Aly, Y. Zhou, K.T. Dupuis, A. Bilbao Pena, V.L. Paurus, and D.J. Orton, et al. 2017. "A structural examination and collision cross section database for over 500 metabolites and xenobiotics using drift tube ion mobility spectrometry." Chemical Science 8, no. 11:7724-7736. PNNL-SA-126802. doi:10.1039/C7SC03464D
Zheng X, RD Smith, and EM Baker. 2018. "Recent Advances in Lipid Separations and Structural Elucidation Using Mass Spectrometry Combined with Ion Mobility Spectrometry, Ion-Molecule Reactions and Fragmentation Approaches." Current Opinion in Chemical Biology 42:111-118. doi:10.1016/j.cbpa.2017.11.009
Zheng X, RS Renslow, MM Makola, IK Webb, L Deng, DG Thomas, N Govind, YM Ibrahim, MM Kabanda, IA Dubery, HM Heyman, RD Smith, NE Madala, and EM Baker. 2017. "Structural Elucidation of cis/trans Dicaffeoylquinic Acid Photoisomerization Using Ion Mobility Spectrometry-Mass Spectrometry." The Journal of Physical Chemistry Letters 8(7):1381-1388. doi:10.1021/acs.jpclett.6b03015
Zheng X., R. Wojcik, X. Zhang, Y.M. Ibrahim, K.E. Burnum-Johnson, D.J. Orton, and M.E. Monroe, et al. 2017. "Coupling Front-end Separations, Ion Mobility Spectrometry, and Mass Spectrometry for Enhanced Multidimensional Biological and Environmental Analyses." Annual Review of Analytical Chemistry 10. PNNL-SA-121198. doi:10.1146/annurev-anchem-061516-045212
Zhu Y., G. Clair, W.B. Chrisler, Y. Shen, A.K. Shukla, R.J. Moore, and R.D. Smith, et al. 2018. "Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC-MS." Angewandte Chemie International Edition 57, no. 38:12370-12374. PNNL-SA-132946. doi:10.1002/anie.201802843
Zhu Y., M. Dou, P.D. Piehowski, Y. Liang, F. Wang, R.K. Chu, and W.B. Chrisler, et al. 2018. "Spatially Resolved Proteome Mapping of Laser Capture Microdissected Tissue with Automated Sample Transfer to Nanodroplets." Molecular and Cellular Proteomics 17, no. 9:1864-1874. PNNL-SA-138815. doi:10.1074/mcp.TIR118.000686
Zhu Y., P.D. Piehowski, R. Zhao, J. Chen, Y. Shen, R.J. Moore, and A.K. Shukla, et al. 2018. "Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells." Nature Communications 9, no. 1:882. PNNL-SA-125235. doi:10.1038/s41467-018-03367-w
Zhu Y, Piehowski PD, Kelly RT, Qian WJ (2018) Nanoproteomics comes of age. Expert Rev Proteomics 15: 865?871.
Zhu Y., R. Zhao, P.D. Piehowski, R.J. Moore, S. Lim, V.J. Orphan, and L. Pasa Tolic, et al. 2018. "Subnanogram proteomics: impact of LC column selection, MS instrumentation and data analysis strategy on proteome coverage for trace samples." International Journal of Mass Spectrometry 427. PNNL-SA-125645. doi:10.1016/j.ijms.2017.08.016