Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'
EMSL Project ID
49531
Abstract
Collaborative research projects in the PNNL NIH P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'
Project Details
Start Date
2016-07-11
End Date
2018-09-30
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Hanging drop sample preparation improves sensitivity of spatial proteomics
Yumi Kwon, Paul D. Piehowski, Rui Zhao, Ryan L. Sontag, Ronald J. Moore, Kristin E. Burnum-Johnson, Richard D. Smith, Wei-Jun Qian, Ryan T. Kelly, Ying Zhu. 2022. "Hanging drop sample preparation improves sensitivity of spatial proteomics." Lab on a Chip 22 (15):2869-2877. https://doi.org/10.1039/d2lc00384h
Multi-platform ’Omics Analysis of Human Ebola Virus Disease Pathogenesis
Eisfeld A.J., P. Halfmann, J.P. Wendler, J.E. Kyle, K.E. Burnum-Johnson, Z. Peralta, and T. Maemura, et al. 2017. "Multi-platform 'Omics Analysis of Human Ebola Virus Disease Pathogenesis." Cell Host & Microbe 22, no. 6:817-829. PNNL-SA-120881. doi:10.1016/j.chom.2017.10.011
Position-dependent termination and widespread obligatory frameshifting in Euplotes translation
Lobanov A.V., S.M. Heaphy, A.A. Turanov, M.V. Gerashchenko, S. Pucciarelli, R.R. Devaraj, and F. Xie, et al. 2017. "Position-dependent termination and widespread obligatory frameshifting in Euplotes translation." Nature Structural & Molecular Biology 24, no. 1:61-68. PNNL-SA-123907. doi:10.1038/nsmb.3330
Activity-Based Probes for Isoenzyme- and Site-Specific Functional Characterization of Glutathione S-Transferases
Stoddard E.G., B.J. Killinger, R.N. Nair, N.C. Sadler, R.F. Volk, S.O. Purvine, and A.K. Shukla, et al. 2017. "Activity-Based Probes for Isoenzyme- and Site-Specific Functional Characterization of Glutathione S- Transferases." Journal of the American Chemical Society 139, no. 45:16032-16035. PNNL-SA-127421. doi:10.1021/jacs.7b07378
Compression Ratio Ion Mobility Programming (CRIMP) Accumulation and Compression of Billions of Ions for Ion Mobility-Mass Spectrometry Using Traveling Waves in Structures for Lossless Ion Manipulations (SLIM)
Deng L., V. Garimella, A.M. Hamid, I.K. Webb, I.K. Attah, R.V. Norheim, and S.A. Prost, et al. 2017. "Compression Ratio Ion Mobility Programming (CRIMP) Accumulation and Compression of Billions of Ions for Ion Mobility-Mass Spectrometry Using Traveling Waves in Structures for Lossless Ion Manipulations (SLIM)." Analytical Chemistry 89, no. 12:6432-6439. PNNL-SA-123357. doi:10.1021/acs.analchem.7b00189
Traveling-Wave-Based Electrodynamic Switch for Concurrent Dual-Polarity Ion Manipulations in Structures for Lossless Ion Manipulations
Attah I.K., G. Nagy, V. Garimella, R.V. Norheim, G.A. Anderson, Y.M. Ibrahim, and R.D. Smith. 2019. "Traveling wave-based electrodynamic switch for concurrent dual polarity ion manipulations in Structures for Lossless Ion Manipulations." Analytical Chemistry 91. PNNL-SA-147653. doi:10.1021/acs.analchem.9b03987
Dual Polarity Ion Confinement and Mobility Separations
Attah I.K., V. Garimella, I.K. Webb, G. Nagy, R.V. Norheim, C.E. Schimelfenig, and Y.M. Ibrahim, et al. 2019. "Dual Polarity Ion Confinement and Mobility Separations." Journal of the American Society for Mass Spectrometry 30, no. 6:967-976. PNNL-SA-146246. doi:10.1007/s13361-019-02138-1
Proteomic studies of bone and skeletal health outcomes
Nielson C., J.M. Jacobs, and E.S. Orwoll. 2019. "Proteomic studies of bone and skeletal health outcomes." Bone 126. PNNL-SA-147327. doi:10.1016/j.bone.2019.03.032
SLIM Ultrahigh Resolution Ion Mobility Spectrometry Separations of Isotopologues and Isotopomers Reveal Mobility Shifts due to Mass Distribution Changes
Wojcik R., G. Nagy, I.K. Attah, I.K. Webb, V. Garimella, K.K. Weitz, and A.L. Hollerbach, et al. 2019. "SLIM Ultrahigh Resolution Ion Mobility Spectrometry Separations of Isotopologues and Isotopomers Reveal Mobility Shifts due to Mass Distribution Changes." Analytical Chemistry 91, no. 18:11952-11962. PNNL-SA-147394. doi:10.1021/acs.analchem.9b02808
Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites
Dickinson M., L.N. Anderson, B.M. Webb-Robertson, J.R. Hansen, R.D. Smith, A.T. Wright, and K. Hybiske. 2019. "Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites." PLoS Pathogens 15, no. 4:Article Number e1007698. PNNL-SA-132851. doi:10.1371/journal.ppat.1007698
A Targeted Mass Spectrometric Assay for Reliable Sensitive Hepcidin Quantification
Moghieb A.M., L. Tesfay, S. Nie, M.A. Gritsenko, T.L. Fillmore, J.M. Jacobs, and R.D. Smith, et al. 2019. "A Targeted Mass Spectrometric Assay for Reliable Sensitive Hepcidin Quantification." Scientific Reports 9. PNNL-SA-138022. doi:10.1038/s41598-019-43756-9
Opening new paths for biological applications of ion mobility - Mass spectrometry using structures for lossless ion manipulations
Garimella V., G. Nagy, Y.M. Ibrahim, and R.D. Smith. 2019. "Opening new paths for biological applications of ion mobility - Mass spectrometry using structures for lossless ion manipulations." Trends in Analytical Chemistry. TrAC 116. PNNL-SA-140349. doi:10.1016/j.trac.2019.04.021
Micropuncture of Bowman's Space in Mice Facilitated by 2 Photon Microscopy
Matsushita K., K. Golgotiu, D.J. Orton, R.D. Smith, K.D. Rodland, P.D. Piehowski, and M.P. Hutchens. 2018. "Micropuncture of Bowman's Space in Mice Facilitated by 2 Photon Microscopy." Journal of Visual Experiments 140. PNNL-SA-137928. doi:10.3791/58206
Ion Mobility-Mass Spectrometry in Metabolomic, Lipidomic, and Proteomic Analyses
Chouinard C.D., G. Nagy, R.D. Smith, and E.M. Baker. 2019. "Ion Mobility-Mass Spectrometry in Metabolomic, Lipidomic, and Proteomic Analyses." In Comprehensive Analytical Chemistry. 123-159. PNNL-SA-137883. doi:10.1016/bs.coac.2018.11.001
Proximity-dependent proteomics of theChlamydia trachomatisinclusion membrane reveals functional interactions with endoplasmic reticulum exit sites
Dickinson M., L.N. Anderson, B.M. Webb-Robertson, J.R. Hansen, R.D. Smith, A.T. Wright, and K. Hybiske. 2018. "Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites." bioRxiv. PNNL-SA-132851. doi:10.1101/285106.
Separation of β-Amyloid Tryptic Peptide Species with Isomerized and Racemized l-Aspartic Residues with Ion Mobility in Structures for Lossless Ion Manipulations
Nagy G., K. Kedia, I.K. Attah, V. Garimella, Y.M. Ibrahim, V.A. Petyuk, and R.D. Smith. 2019. "Separation of ß-Amyloid Tryptic Peptide Species with Isomerized and Racemized L-Aspartic Residues with Ion Mobility in Structures for Lossless Ion Manipulations." Analytical Chemistry. PNNL-SA-138885. doi:10.1021/acs.analchem.8b04696.
Rapidly Assessing the Quality of Targeted Proteomics Experiments through Monitoring Stable-Isotope Labeled Standards
Gibbons B.C., T.L. Fillmore, Y. Gao, R.J. Moore, T. Liu, E.S. Nakayasu, and T.O. Metz, et al. 2019. "Rapidly Assessing the Quality of Targeted Proteomics Experiments through Monitoring Stable-Isotope Labeled Standards." Journal of Proteome Research 18, no. 2:694-699. PNNL-SA-137457. doi:10.1021/acs.jproteome.8b00688
Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations
Schwartz J.B., C. Gallagher, R. Jorde, V. Berg, J. Walsh, R. Eastell, and A.L. Evans, et al. 2018. "Determination of free 25(OH)D concentrations and their relationships to total 25(OH)D in multiple clinical populations." The Journal of Clinical Endocrinology and Metabolism 103, no. 9:3278–3288. PNNL-SA-138870. doi:10.1210/jc.2018-00295
Towards resolving the spatial metabolome with unambiguous molecular annotations in complex biological systems by coupling mass spectrometry imaging with structures for lossless ion manipulations
Nagy G., D. Velickovic, R.K. Chu, A.A. Carrell, D.J. Weston, Y.M. Ibrahim, and C.R. Anderton, et al. 2018. "Towards Resolving the Spatial Metabolome with Unambiguous Molecular Annotations in Complex Biological Systems by Coupling Mass Spectrometry Imaging with Structures for Lossless Ion Manipulations." Chemical Communications. PNNL-SA-138045. doi:10.1039/C8CC07482H
Distinguishing enantiomeric amino acids with chiral cyclodextrin adducts and structures for lossless ion manipulations
Nagy G., C.D. Chouinard, I.K. Attah, I.K. Webb, V. Garimella, Y.M. Ibrahim, and E.M. Baker, et al. 2019. "Distinguishing Enantiomeric Amino Acids with Chiral Cyclodextrin Adducts and Structures for Lossless Ion Manipulations." Electrophoresis 39, no. 24:3148–3155. PNNL-SA-136376. doi:10.1002/elps.201800294
Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations
Nagy G., I.K. Attah, V. Garimella, Y.M. Ibrahim, E.M. Baker, and R.D. Smith. 2018. "Unraveling the Isomeric Heterogeneity of Glycans: Ion Mobility Separations in Structures for Lossless Ion Manipulations." Chemical Communications 54, no. 83:11701-11704. PNNL-SA-137134. doi:10.1039/C8CC06966B
Utilizing ion mobility spectrometry and mass spectrometry for the analysis of polycyclic aromatic hydrocarbons, polychlorinated biphenyls, polybrominated diphenyl ethers and their metabolites
Zheng X., K.T. Dupuis, N.A. Aly, Y. Zhou, F.B. Smith, K. Tang, and R.D. Smith, et al. 2018. "Utilizing Ion Mobility Spectrometry and Mass Spectrometry for the Analysis of Polycyclic Aromatic Hydrocarbons, Polychlorinated Biphenyls, Polybrominated Diphenyl Ethers and Their Metabolites." Analytical Chimica Acta 1037. PNNL-SA-130591. doi:10.1016/j.aca.2018.02.054
Coupling Front-End Separations, Ion Mobility Spectrometry, and Mass Spectrometry For Enhanced Multidimensional Biological and Environmental Analyses
Zheng X., R. Wojcik, X. Zhang, Y.M. Ibrahim, K.E. Burnum-Johnson, D.J. Orton, and M.E. Monroe, et al. 2017. "Coupling Front-end Separations, Ion Mobility Spectrometry, and Mass Spectrometry for Enhanced Multidimensional Biological and Environmental Analyses." Annual Review of Analytical Chemistry 10. PNNL-SA-121198. doi:10.1146/annurev-anchem-061516-045212
An efficient method for native protein purification in the selected range from prostate cancer tissue digests
Ahmad R., C.D. Nicora, A.K. Shukla, R.D. Smith, W. Qian, and A.Y. Liu. 2016. "An efficient method for native protein purification in the selected range from prostate cancer tissue digests." Chinese Clinical Oncology 5, no. 6:78. PNNL-SA-123158. doi:10.21037/cco.2016.12.03
New frontiers for mass spectrometry based upon structures for lossless ion manipulations
Ibrahim Y.M., A.M. Hamid, L. Deng, V. Garimella, I.K. Webb, E.M. Baker, and R.D. Smith. 2017. "New Frontiers for Mass Spectrometry based upon Structures for Lossless Ion Manipulations." Analyst 142, no. 7:1010-1021. PNNL-SA-123137. doi:10.1039/C7AN00031F
A structural examination and collision cross section database for over 500 metabolites and xenobiotics using drift tube ion mobility spectrometry
Zheng X., N.A. Aly, Y. Zhou, K.T. Dupuis, A. Bilbao Pena, V.L. Paurus, and D.J. Orton, et al. 2017. "A structural examination and collision cross section database for over 500 metabolites and xenobiotics using drift tube ion mobility spectrometry." Chemical Science 8, no. 11:7724-7736. PNNL-SA-126802. doi:10.1039/C7SC03464D
Improved Sensitivity and Separations for Phosphopeptides using Online Liquid Chromotography Coupled with Structures for Lossless Ion Manipulations Ion Mobility–Mass Spectrometry
Chouinard C.D., G. Nagy, I.K. Webb, T. Shi, E.M. Baker, S.A. Prost, and T. Liu, et al. 2018. "Improved Sensitivity and Separations for Phosphopeptides using Online LC Coupled with Structures for Lossless Ion Manipulations (SLIM) IM-MS." Analytical Chemistry 90, no. 18:10889-10896. PNNL-SA-135107. doi:10.1021/acs.analchem.8b02397
Rapid Ion Mobility Separations of Bile Acid Isomers Using Cyclodextrin Adducts and Structures for Lossless Ion Manipulations
Chouinard C.D., G. Nagy, I.K. Webb, V. Garimella, E.M. Baker, Y.M. Ibrahim, and R.D. Smith. 2018. "Rapid Ion Mobility Separations of Bile Acid Isomers Using Cyclodextrin Adducts and Structures for Lossless Ion Manipulations." Analytical Chemistry 90, no. 18:11086-11091. PNNL-SA-136059. doi:10.1021/acs.analchem.8b02990
A Global Survey of ATPase Activity in Plasmodium falciparum Asexual Blood Stages and Gametocytes
Ortega C., A. Frando, B.M. Webb-Robertson, L.N. Anderson, N. Fleck, E.L. Flannery, and M. Fishbaugher, et al. 2018. "A global survey of ATPase activity in Plasmodium falciparum asexual blood stages and gametocytes." Molecular and Cellular Proteomics 17, no. 1:111-120. PNNL-SA-121236. doi:10.1074/mcp.RA117.000088
Facile carrier-assisted targeted mass spectrometric approach for proteomic analysis of low numbers of mammalian cells
Shi T., M.J. Gaffrey, T.L. Fillmore, C.D. Nicora, L. Yi, A.K. Shukla, and H. Wiley, et al. 2018. "Facile carrier-assisted targeted mass spectrometric approach for single-cell proteomics analysis." Nature Methods. PNNL-SA-130600. doi:10.1038/s42003-018-0107-6
Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins
Shi T., S. Quek, Y. Gao, C.D. Nicora, S. Nie, T.L. Fillmore, and T. Liu, et al. 2017. "Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins." Oncotarget 8, no. 60:101887-101898. PNNL-SA-128413. doi:10.18632/oncotarget.21710
The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target
Petyuk V.A., R.R. Chang, M. Ramirez Restrepo, N.B. Bechmann, M.Y. Henrion, P.D. Piehowski, and K. Zhu, et al. 2018. "The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target." Brain 141, no. 9:2721–2739. PNNL-SA-133886. doi:10.1093/brain/awy215
A transcriptomic atlas of aged human microglia
Olah M., E. Patrick, A. Villani, J. Xu, C. White, K. Ryan, and P.D. Piehowski, et al. 2018. "A transcriptomic atlas of aged human microglia." Nature Communications 9. PNNL-SA-134273. doi:10.1038/s41467-018-02926-5
Subnanogram proteomics: Impact of LC column selection, MS instrumentation and data analysis strategy on proteome coverage for trace samples
Zhu Y., R. Zhao, P.D. Piehowski, R.J. Moore, S. Lim, V.J. Orphan, and L. Pasa Tolic, et al. 2018. "Subnanogram proteomics: impact of LC column selection, MS instrumentation and data analysis strategy on proteome coverage for trace samples." International Journal of Mass Spectrometry 427. PNNL-SA-125645. doi:10.1016/j.ijms.2017.08.016
Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells
Zhu Y., P.D. Piehowski, R. Zhao, J. Chen, Y. Shen, R.J. Moore, and A.K. Shukla, et al. 2018. "Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells." Nature Communications 9, no. 1:882. PNNL-SA-125235. doi:10.1038/s41467-018-03367-w
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia
Yu L., V.A. Petyuk, C. Gaiteri, S. Mostafavi, T. Young-Pearse, R.C. Shah, and A. Buchman, et al. 2018. "Targeted Brain Proteomics Uncover Multiple Pathways to Alzheimer’s Dementia." Annals of Neurology 84, no. 1:78-88. PNNL-SA-136156. doi:10.1002/ana.25266
Fatiguing contractions increase protein S-glutathionylation occupancy in mouse skeletal muscle
Kramer P.A., J. Duan, M.J. Gaffrey, A.K. Shukla, L.L. Wang, T. Bammler, and W. Qian, et al. 2018. "Fatiguing Contractions Increase Protein S-Glutathionylation Occupancy in Mouse Skeletal Muscle." Redox Biology 17. PNNL-SA-135523. doi:10.1016/j.redox.2018.05.011
A Customizable Flow Injection System for Automated, High Throughput, and Time Sensitive Ion Mobility Spectrometry and Mass Spectrometry Measurements
Orton D.J., M.M. Tfaily, R.J. Moore, B.L. Lamarche, X. Zheng, T.L. Fillmore, and R.K. Chu, et al. 2018. "A Customizable Flow Injection System for Automated, High Throughput and Time Sensitive Ion Mobility Spectrometry and Mass Spectrometry Measurements." Analytical Chemistry 90, no. 1:737-744. PNNL-SA-128111. doi:10.1021/acs.analchem.7b02986
Application of multiplexed ion mobility spectrometry towards the identification of host protein signatures of treatment effect in pulmonary tuberculosis
Kedia K., J.P. Wendler, E.M. Baker, K.E. Burnum-Johnson, L.G. Jarsberg, K.G. Stratton, and A.T. Wright, et al. 2018. "Application of multiplexed ion mobility spectrometry towards the identification of host protein signatures of treatment effect in pulmonary tuberculosis." Tuberculosis 112. PNNL-SA-137966. doi:10.1016/j.tube.2018.07.005
Mass spectrometry-based proteomics for system-level characterization of biological responses to engineered nanomaterials
Qian W. 2018. "Mass spectrometry-based proteomics for systems-level characterization of biological responses to engineered nanomaterials." Analytical and Bioanalytical Chemistry 410, no. 24:6067-6077. PNNL-SA-133275. doi:10.1007/s00216-018-1168-6
Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC-MS
Zhu Y., G. Clair, W.B. Chrisler, Y. Shen, A.K. Shukla, R.J. Moore, and R.D. Smith, et al. 2018. "Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC-MS." Angewandte Chemie International Edition 57, no. 38:12370-12374. PNNL-SA-132946. doi:10.1002/anie.201802843
Characterization of applied fields for ion mobility separations in traveling wave based structures for lossless ion manipulations (SLIM)
Hamid A.M., A. Prabhakaran Nair Syamala Amma, V. Garimella, Y.M. Ibrahim, and R.D. Smith. 2018. "Characterization of applied fields for ion mobility in traveling wave based structures for lossless ion manipulations (SLIM)." International Journal of Mass Spectrometry 430. PNNL-SA-127372. doi:10.1016/j.ijms.2018.03.006
Pyroptosis by caspase11/4‐gasdermin‐D pathway in alcoholic hepatitis in mice and patients
Bakhanova E.V., R. Wu, W. Wang, R. Yan, Y. Chen, S. French, and C. Llorente, et al. 2018. "Pyroptosis by Caspase11/4-Gasdermin-D Pathway in Alcoholic Hepatitis." Hepatology 67, no. 5:1737-1753. PNNL-SA-130597. doi:10.1002/hep.29645
An algorithm to correct saturated mass spectrometry ion abundances for enhanced quantitation and mass accuracy in omic studies
Bilbao Pena A., B.C. Gibbons, G.W. Slysz, K.L. Crowell, M.E. Monroe, Y.M. Ibrahim, and R.D. Smith, et al. 2018. "An Algorithm to Correct Saturated Mass Spectrometry Ion Abundances for Enhanced Quantitation and Mass Accuracy in Omic Studies." International Journal of Mass Spectrometry 427. PNNL-SA-126312. doi:10.1016/j.ijms.2017.11.003
Towards Discovery and Targeted Peptide Biomarker Detection Using nanoESI-TIMS-TOF MS
Garabedian A., P. Benigni, C. Ramirez, E.M. Baker, T. Liu, R.D. Smith, and F. Fernandez-Lima. 2018. "Towards Discovery and Targeted Peptide Biomarker Detection Using nanoESI-TIMS-TOF MS." Journal of the American Society for Mass Spectrometry 29, no. 5:817-826. PNNL-SA-129610. doi:10.1007/s13361-017-1787-8
Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway
Yi L., T. Shi, M.A. Gritsenko, C. Chan, T.L. Fillmore, B.M. Hess, and A.C. Swensen, et al. 2018. "Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway." Analytical Chemistry 90, no. 8:5256-5263. PNNL-SA-131519. doi:10.1021/acs.analchem.8b00071
Evaluating lipid mediator structural complexity using ion mobility spectrometry combined with mass spectrometry
Kyle JE, NA Aly, X Zheng, KE Burnum-Johnson, RD Smith, and EM Baker. 2018. "Evaluating Lipid Mediator Structural Complexity Using Ion Mobility Spectrometry." Bioanalysis 10(5):279-289. doi:10.4155/bio-2017-0245
Recent advances in lipid separations and structural elucidation using mass spectrometry combined with ion mobility spectrometry, ion-molecule reactions and fragmentation approaches
Zheng X, RD Smith, and EM Baker. 2018. "Recent Advances in Lipid Separations and Structural Elucidation Using Mass Spectrometry Combined with Ion Mobility Spectrometry, Ion-Molecule Reactions and Fragmentation Approaches." Current Opinion in Chemical Biology 42:111-118. doi:10.1016/j.cbpa.2017.11.009
High-throughput serum proteomics for the identification of protein biomarkers of mortality in older men
Orwoll ES, J Wiedrick, JM Jacobs, EM Baker, PD Piehowski, VA Petyuk, Y Gao, T Shi, RD Smith, DC Bauer, SR Cummings, C Nielson, and J Lapidus. 2018. "High throughput serum proteomics for the identification of protein biomarkers of mortality in older men." Aging Cell 17(2):UNSP e12717. doi:10.1111/acel.12717
Online Ozonolysis Combined with Ion Mobility-Mass Spectrometry Provides a New Platform for Lipid Isomer Analyses
Poad BL, X Zheng, TA Mitchell, RD Smith, EM Baker, and SJ Blanksby. 2018. "Online ozonolysis combined with ion mobility-mass spectrometry provides a new platform for lipid isomer analyses." Analytical Chemistry 90(2):1292-1300. doi:10.1021/acs.analchem.7b04091
A Hybrid Constant and Oscillatory Field Ion Mobility Analyzer Using Structures for Lossless Ion Manipulations
Prabhakaran Nair Syamala Amma A, AM Hamid, VBS Garimella, BR Valenzuela, RG Ewing, YM Ibrahim, and RD Smith. 2018. "A Hybrid Constant and Oscillatory Field Ion Mobility Analyzer in Structures for Lossless Ion Manipulations." Journal of the American Society for Mass Spectrometry 29(2):342-351. doi:10.1007/s13361-017-1841-6
Advances in microscale separations towards nanoproteomics applications
Yi L, PD Piehowski, T Shi, RD Smith, and W Qian. 2017. "Advances in Microscale Separations towards Nanoproteomics Applications." Journal of Chromatography A. 1523:40-48. doi:10.1016/j.chroma.2017.07.055
An Interlaboratory Evaluation of Drift Tube Ion Mobility–Mass Spectrometry Collision Cross Section Measurements
Causon T J,Zheng X ,Kurulugama Lekamlage R T,Rennie E E,Baker E M,Smith R D,McLean J ,Hann S ,Fjeldsted J C,May J C,Mairinger T ,Stow S 2017. "An Interlaboratory Evaluation of Drift Tube Ion Mobility?Mass" Analytical Chemistry 89(17):9048–9055. 10.1021/acs.analchem.7b01729
Changes of Protein Turnover in Aging Caenorhabditis elegans
Smith RD, I Dhondt, VA Petyuk, HM Brewer, GG Depuydt, BP Braeckman, and S Bauer. 2017. "Changes of Protein Turnover in Aging Caenorhabditis elegans." Molecular & Cellular Proteomics. MCP 16:1621-1633. doi:10.1074/mcp.RA117.000049
Design of a TW-SLIM Module for Dual Polarity Confinement, Transport, and Reactions
Garimella VBS, IK Webb, A Prabhakaran Nair Syamala Amma, IK Attah, YM Ibrahim, and RD Smith. 2017. "DESIGN OF TW-SLIM FOR DUAL POLARITY CONFINEMENT, TRANSPORT AND REACTIONS." Journal of the American Society for Mass Spectrometry 28(7):1442-1449. doi:10.1007/s13361-017-1680-5
Distinguishing d- and l-aspartic and isoaspartic acids in amyloid β peptides with ultrahigh resolution ion mobility spectrometry
Zheng X, L Deng, EM Baker, YM Ibrahim, VA Petyuk, and RD Smith. 2017. "Distinguishing D- and L-Aspartic and Isoaspartic Acids in Amyloid ? Peptides with Ultrahigh Resolution Ion Mobility Spectrometry." Chemical Communications 53(56):7913-7916. doi:10.1039/C7CC03321D
A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination
Qiu J, K Yu, X Fei, Y Liu, ES Nakayasu, PD Piehowski, JB Shaw, K Puvar, C Das, X Liu, and ZQ Luo. 2017. "A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination." Cell Research 27(7):865-881. doi:10.1038/cr.2017.66
Identification of Hip BMD Loss and Fracture Risk Markers Through Population-Based Serum Proteomics
Nielson C, J Wiedrick, J Shen, JM Jacobs, EM Baker, A Baraff, PD Piehowski, C Lee, A Baratt, VA Petyuk, SK Mcweeney, JY Lim, DC Bauer, NE Lane, PM Cawthon, RD Smith, J Lapidus, and ES Orwoll. 2017. "Identification of Hip BMD Loss and Fracture Risk Markers Through Population-Based Serum Proteomics." Journal of Bone and Mineral Research 32(7):1559-1567. doi:10.1002/jbmr.3125
Squeezing of Ion Populations and Peaks in Traveling Wave Ion Mobility Separations and Structures for Lossless Ion Manipulations Using Compression Ratio Ion Mobility Programming
Garimella VBS, AM Hamid, L Deng, YM Ibrahim, IK Webb, EM Baker, SA Prost, RV Norheim, GA Anderson, and RD Smith. 2016. "Squeezing of Ion Populations and Peaks in Traveling Wave Ion Mobility Separations and Structures for Lossless Ion Manipulations using Compression Ratio Ion Mobility Programming." Analytical Chemistry 88(23):11877-11885. doi:10.1021/acs.analchem.6b03660
Quantitative proteomic characterization of redox-dependent post-translational modifications on protein cysteines
Duan J, MJ Gaffrey, and W Qian. 2017. "Quantitative Proteomic Characterization of Redox-dependent Post-translational Modifications on Protein Cysteines." Molecular Biosystems 13(5):816-829. doi:10.1039/c6mb00861e
Serpentine Ultralong Path with Extended Routing (SUPER) High Resolution Traveling Wave Ion Mobility-MS using Structures for Lossless Ion Manipulations
Deng L, IK Webb, VBS Garimella, AM Hamid, X Zheng, RV Norheim, SA Prost, GA Anderson, JA Sandoval, EM Baker, YM Ibrahim, and RD Smith. 2017. "Serpentine Ultralong Path with Extended Routing (SUPER) High Resolution Traveling Wave Ion Mobility-MS using Structures for Lossless Ion Manipulations." Analytical Chemistry 89(8):4628–4634. doi:10.1021/acs.analchem.7b00185
Structural Elucidation of cis/trans Dicaffeoylquinic Acid Photoisomerization Using Ion Mobility Spectrometry-Mass Spectrometry
Zheng X, RS Renslow, MM Makola, IK Webb, L Deng, DG Thomas, N Govind, YM Ibrahim, MM Kabanda, IA Dubery, HM Heyman, RD Smith, NE Madala, and EM Baker. 2017. "Structural Elucidation of cis/trans Dicaffeoylquinic Acid Photoisomerization Using Ion Mobility Spectrometry-Mass Spectrometry." The Journal of Physical Chemistry Letters 8(7):1381-1388. doi:10.1021/acs.jpclett.6b03015
Comparing identified and statistically significant lipids and polar metabolites in 15-year old serum and dried blood spot samples for longitudinal studies
Kyle JE, CP Casey, KG Stratton, EM Zink, YM Kim, X Zheng, ME Monroe, KK Weitz, KJ Bloodsworth, DJ Orton, YM Ibrahim, RJ Moore, C Lee, C Pedersen, ES Orwoll, RD Smith, KE Burnum-Johnson, and EM Baker. 2017. "Comparing Identified and Statistically Significant Lipids and Metabolites in 15-Year Old Serum and Dried Blood Spot Samples for Longitudinal Studies." Rapid Communications in Mass Spectrometry 31(5):447-456. doi:10.1002/rcm.7808
Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations
Nielson C ,Jones K ,Chun R F,Jacobs J M,Wang Y ,Hewison M ,Adams J S,Swanson C ,Lee C ,Vanderschueren D ,Pauwels S ,Prentice A ,Smith R D,Shi T ,Gao Y ,Schepmoes A A,Zmuda J M,Lapidus J ,Cauley J A,Bouillon R ,Schoenmakers I ,Orwoll E S 2016. "Free 25-hydroxyvitamin D: impact of vitamin D" Journal of Clinical Endocrinology and Metabolism 101(5):2226–2234. 10.1210/jc.2016-1104