FSFA: MOSAIC -- Metabolic and Spatial Interactions in Communities FY18 proposal
EMSL Project ID
50024
Abstract
This EMSL user proposal is to support the MOSAIC DOE BER funded FSFA at PNNL. The primary activities involving EMSL are a set of BSSD demonstration tasks focusing on key science questions and related capabilities which are expected to be relevant to future BER research interests. These tasks, summarized in the EMSL proposal, share a common focus on understanding interactions between microbes and their extracellular environments, and how these associations contribute to functional stability and robustness. Advances in metabolomics and related techniques will be coupled with models to codify new understanding. Planned outcomes include new capabilities and related publications.
Project Details
Start Date
2017-10-01
End Date
2018-09-30
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
Colby S.M., D.G. Thomas, J. Nunez, D.J. Baxter, K.R. Glaesemann, J.M. Brown, and M.A. Pirrung, et al. 2019. "ISiCLE: A Quantum Chemistry Pipeline for Establishing in Silico Collision Cross Section Libraries." Analytical Chemistry 91, no. 7:4346-4356. PNNL-SA-138476. doi:10.1021/acs.analchem.8b04567
Nobela O., R.S. Renslow, D.G. Thomas, S.M. Colby, S. Sitha, L. Sitole, and P.B. Njobeh, et al. 2018. "Efficient discrimination of natural stereoisomers of chicoric acid, an HIV-1 integrase inhibitor." JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 189. PNNL-SA-137796. doi:10.1016/j.jphotobiol.2018.10.025
Shen Y., R. Zhao, N. Tolic, M. Tfaily, E.W. Robinson, R.M. Boiteau, and L. Pasa Tolic, et al. 2019. "Online supercritical fluid extraction mass spectrometry (SFE-LC-FTMS) for sensitive characterization of soil organic matter." Faraday Discussions 218. PNNL-SA-141115. doi:10.1039/C9FD00011A